id,gene_symbol,protein_name,activation_state_pdb_active,activation_state_pdb_inactive,opentargets_top_disease_name,priority_score
P05106,ITGB3,Integrin beta-3,8T2U,8T2V,Glanzmann thrombasthenia 1,0.715
P11802,CDK4,Cyclin-dependent kinase 4,2W96,3G33,"melanoma, cutaneous malignant, susceptibility to, 3",0.575
P06756,ITGAV,Integrin alpha-V,1L5G,1JV2,neurodegenerative disease,0.572
P08514,ITGA2B,Integrin alpha-IIb,8T2U,8T2V,Glanzmann thrombasthenia 1,0.515
P00519,ABL1,Tyrosine-protein kinase ABL1,2GQG,1OPL,chronic myelogenous leukemia,0.0
P01112,HRAS,GTPase HRas,5P21,4Q21,Costello syndrome,0.0
P01116,KRAS,GTPase KRas,6GOD,6MNX,Noonan syndrome 3,0.0
P12931,SRC,Proto-oncogene tyrosine-protein kinase Src,1Y57,2SRC,cancer,0.0
P24941,CDK2,Cyclin-dependent kinase 2,1QMZ,1HCK,neurodegenerative disease,0.0
P31749,AKT1,RAC-alpha serine/threonine-protein kinase,4EJN,3O96,Proteus syndrome,0.0
O14965,AURKA,Aurora kinase A,1OL5,1MUO,neurodegenerative disease,