gene_symbol,protein_name,surface_class,targetability_score,pdb_count,top_disease,disease_score,surface_evidence
SLC2A1,"Solute carrier family 2, facilitated glucose transporter member 1",A_surface,2.756,5,encephalopathy due to GLUT1 deficiency,0.8521823225896756,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"
GP1BA,Platelet glycoprotein Ib alpha chain,A_surface,2.75,22,Bernard-Soulier syndrome,0.8346884735388165,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
ITGA2B,Integrin alpha-IIb,A_surface,2.747,78,Glanzmann thrombasthenia 1,0.8224288672248264,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
GP9,Platelet glycoprotein IX,A_surface,2.747,2,Bernard-Soulier syndrome,0.8233582238860002,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
SLC4A1,Band 3 anion transport protein,A_surface,2.746,54,hereditary spherocytosis type 4,0.820137113225454,"HPA protein class = Blood group antigen proteins, CD markers (cell-surface, extracellular epitope)"
ITGB3,Integrin beta-3,A_surface,2.746,123,Glanzmann thrombasthenia 1,0.8208115968652424,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
CD36,Platelet glycoprotein 4,A_surface,2.721,1,platelet-type bleeding disorder 10,0.7360571429413174,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
PTPRC,Receptor-type tyrosine-protein phosphatase C,A_surface,2.716,6,immunodeficiency 104,0.7200430416648742,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
TFRC,Transferrin receptor protein 1,A_surface,2.687,22,TFRC-related combined immunodeficiency,0.623449899069336,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
ITGB1,Integrin beta-1,A_surface,2.676,22,multiple sclerosis,0.586769452063963,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
IGHV3-23,Immunoglobulin heavy variable 3-23,A_surface,2.676,6,cutaneous Leishmaniasis,0.5868213846274001,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"
IGHV1-2,Immunoglobulin heavy variable 1-2,A_surface,2.676,1,cutaneous Leishmaniasis,0.5868213846274001,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"
IGKV4-1,Immunoglobulin kappa variable 4-1,A_surface,2.676,10,cutaneous Leishmaniasis,0.5868213846274001,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"
PTPRJ,Receptor-type tyrosine-protein phosphatase eta,A_surface,2.664,5,neurodegenerative disease,0.54699134609967,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
SNAP23,Synaptosomal-associated protein 23,A_surface,2.659,2,neurodegenerative disease,0.5288361677964304,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"
CD9,CD9 antigen,A_surface,2.658,5,diphtheria,0.5261379875719714,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
ANPEP,Aminopeptidase N,A_surface,2.651,15,cholelithiasis,0.5030146927270738,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
IGHM,Immunoglobulin heavy constant mu,A_surface,2.639,30,agammaglobulinemia,0.4624778576025314,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"
PIGR,Polymeric immunoglobulin receptor,A_surface,2.633,16,clear cell renal carcinoma,0.44260204134234277,"HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)"
ITGA2,Integrin alpha-2,A_surface,2.627,16,Abnormality of the skeletal system,0.4227839911251069,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
SLC2A3,"Solute carrier family 2, facilitated glucose transporter member 3",A_surface,2.622,7,neurodegenerative disease,0.4054698468991856,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"
CD47,Leukocyte surface antigen CD47,A_surface,2.61,15,myelodysplastic syndrome,0.3682348506170252,"HPA protein class = CD markers (cell-surface, extracellular epitope)"
PARVB,Beta-parvin,A_surface,2.584,3,thyroiditis,0.28021156500366357,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"
C1QB,Complement C1q subcomponent subunit B,A_surface,2.5,11,,,"HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)"