{"ok": true, "database": "scout", "query_name": "ev_surface_candidates", "rows": [["SLC2A1", "Solute carrier family 2, facilitated glucose transporter member 1", "A_surface", 2.756, 5, "encephalopathy due to GLUT1 deficiency", 0.8521823225896756, "HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"], ["GP1BA", "Platelet glycoprotein Ib alpha chain", "A_surface", 2.75, 22, "Bernard-Soulier syndrome", 0.8346884735388165, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["ITGA2B", "Integrin alpha-IIb", "A_surface", 2.747, 78, "Glanzmann thrombasthenia 1", 0.8224288672248264, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["GP9", "Platelet glycoprotein IX", "A_surface", 2.747, 2, "Bernard-Soulier syndrome", 0.8233582238860002, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["SLC4A1", "Band 3 anion transport protein", "A_surface", 2.746, 54, "hereditary spherocytosis type 4", 0.820137113225454, "HPA protein class = Blood group antigen proteins, CD markers (cell-surface, extracellular epitope)"], ["ITGB3", "Integrin beta-3", "A_surface", 2.746, 123, "Glanzmann thrombasthenia 1", 0.8208115968652424, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["CD36", "Platelet glycoprotein 4", "A_surface", 2.721, 1, "platelet-type bleeding disorder 10", 0.7360571429413174, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["PTPRC", "Receptor-type tyrosine-protein phosphatase C", "A_surface", 2.716, 6, "immunodeficiency 104", 0.7200430416648742, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["TFRC", "Transferrin receptor protein 1", "A_surface", 2.687, 22, "TFRC-related combined immunodeficiency", 0.623449899069336, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["ITGB1", "Integrin beta-1", "A_surface", 2.676, 22, "multiple sclerosis", 0.586769452063963, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["IGHV3-23", "Immunoglobulin heavy variable 3-23", "A_surface", 2.676, 6, "cutaneous Leishmaniasis", 0.5868213846274001, "HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"], ["IGHV1-2", "Immunoglobulin heavy variable 1-2", "A_surface", 2.676, 1, "cutaneous Leishmaniasis", 0.5868213846274001, "HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"], ["IGKV4-1", "Immunoglobulin kappa variable 4-1", "A_surface", 2.676, 10, "cutaneous Leishmaniasis", 0.5868213846274001, "HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"], ["PTPRJ", "Receptor-type tyrosine-protein phosphatase eta", "A_surface", 2.664, 5, "neurodegenerative disease", 0.54699134609967, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["SNAP23", "Synaptosomal-associated protein 23", "A_surface", 2.659, 2, "neurodegenerative disease", 0.5288361677964304, "HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"], ["CD9", "CD9 antigen", "A_surface", 2.658, 5, "diphtheria", 0.5261379875719714, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["ANPEP", "Aminopeptidase N", "A_surface", 2.651, 15, "cholelithiasis", 0.5030146927270738, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["IGHM", "Immunoglobulin heavy constant mu", "A_surface", 2.639, 30, "agammaglobulinemia", 0.4624778576025314, "HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)"], ["PIGR", "Polymeric immunoglobulin receptor", "A_surface", 2.633, 16, "clear cell renal carcinoma", 0.44260204134234277, "HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)"], ["ITGA2", "Integrin alpha-2", "A_surface", 2.627, 16, "Abnormality of the skeletal system", 0.4227839911251069, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["SLC2A3", "Solute carrier family 2, facilitated glucose transporter member 3", "A_surface", 2.622, 7, "neurodegenerative disease", 0.4054698468991856, "HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"], ["CD47", "Leukocyte surface antigen CD47", "A_surface", 2.61, 15, "myelodysplastic syndrome", 0.3682348506170252, "HPA protein class = CD markers (cell-surface, extracellular epitope)"], ["PARVB", "Beta-parvin", "A_surface", 2.584, 3, "thyroiditis", 0.28021156500366357, "HPA integral membrane protein, Plasma membrane (extracellular domain reachable)"], ["C1QB", "Complement C1q subcomponent subunit B", "A_surface", 2.5, 11, null, null, "HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)"]], "truncated": false, "columns": ["gene_symbol", "protein_name", "surface_class", "targetability_score", "pdb_count", "top_disease", "disease_score", "surface_evidence"], "query": {"sql": "SELECT gene_symbol, protein_name, surface_class, targetability_score, pdb_count, top_disease, disease_score, surface_evidence FROM v_surface_targets WHERE surface_class='A_surface' AND ev_map_hallmark=1 ORDER BY targetability_score DESC", "params": {}}, "error": null, "private": false, "allow_execute_sql": true, "query_ms": 2.7137817814946175, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}