{"ok": true, "database": "scout", "query_name": "ev_with_aptamer", "rows": [["P25445", "FAS", "Tumor necrosis factor receptor superfamily member 6", 1, 17, "autoimmune lymphoproliferative syndrome type 1", 0.914], ["P13747", "HLA-E", "HLA class I histocompatibility antigen, alpha chain E", 1, 1, "COVID-19", 0.865], ["O75581", "LRP6", "Low-density lipoprotein receptor-related protein 6", 1, 5, "tooth agenesis, selective, 7", 0.865], ["Q15848", "ADIPOQ", "Adiponectin", 1, 10, "hearing loss", 0.806], ["P51679", "CCR4", "C-C chemokine receptor type 4", 1, 3, "mycosis fungoides", 0.804], ["P15260", "IFNGR1", "Interferon gamma receptor 1", 1, 2, "disseminated atypical mycobacterial infection", 0.804], ["P02748", "C9", "Complement component C9", 1, 10, "Immunodeficiency due to a late component of complements deficiency", 0.796], ["P13671", "C6", "Complement component C6", 1, 31, "Immunodeficiency due to a late component of complements deficiency", 0.795], ["Q13085", "ACACA", "Acetyl-CoA carboxylase 1", 1, 1, null, 0.79], ["P36888", "FLT3", "Receptor-type tyrosine-protein kinase FLT3", 1, 6, "acute myeloid leukemia", 0.788], ["P04156", "PRNP", "Major prion protein", 1, 2, "Gerstmann-Straussler-Scheinker syndrome", 0.785], ["Q92633", "LPAR1", "Lysophosphatidic acid receptor 1", 1, 1, "Epiretinal membrane", 0.785], ["P14210", "HGF", "Hepatocyte growth factor", 1, 64, "hearing loss, autosomal recessive", 0.78], ["P01019", "AGT", "Angiotensinogen", 1, 16, "renal tubular dysgenesis", 0.779], ["P04839", "CYBB", "NADPH oxidase 2", 1, 2, "chronic granulomatous disease", 0.776], ["P61769", "B2M", "Beta-2-microglobulin", 1, 15, "Immunodeficiency by defective expression of HLA class 1", 0.77], ["P02776", "PF4", "Platelet factor 4", 1, 10, "systemic scleroderma", 0.77], ["P39060", "COL18A1", "Collagen alpha-1(XVIII) chain", 1, 2, "Knobloch syndrome 1", 0.769], ["P01189", "POMC", "Pro-opiomelanocortin", 1, 1, "obesity due to pro-opiomelanocortin deficiency", 0.76], ["P05546", "SERPIND1", "Heparin cofactor 2", 1, 4, "heparin cofactor 2 deficiency", 0.752], ["P43007", "SLC1A4", "Neutral amino acid transporter A", 1, 6, "spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome", 0.75], ["P08648", "ITGA5", "Integrin alpha-5", 1, 2, "skin disease", 0.748], ["P05164", "MPO", "Myeloperoxidase", 1, 16, "myeloperoxidase deficiency", 0.745], ["P15144", "ANPEP", "Aminopeptidase N", 1, 1, "cholelithiasis", 0.74], ["P0C0L4", "C4A", "Complement C4-A", 1, 4, null, 0.74], ["Q03405", "PLAUR", "Urokinase plasminogen activator surface receptor", 1, 2, "Abdominal Aortic Aneurysm", 0.738], ["O60884", "DNAJA2", "DnaJ homolog subfamily A member 2", 1, 2, "dengue disease", 0.73], ["P05187", "ALPP", "Alkaline phosphatase, placental type", 1, 7, "male reproductive organ cancer", 0.72], ["P29622", "SERPINA4", "Kallistatin", 1, 4, "optic atrophy", 0.719], ["Q99988", "GDF15", "Growth/differentiation factor 15", 1, 29, "hyperemesis gravidarum", 0.718], ["P05106", "ITGB3", "Integrin beta-3", 1, 2, "Glanzmann thrombasthenia 1", 0.715], ["P41221", "WNT5A", "Protein Wnt-5a", 1, 4, "Robinow syndrome", 0.71], ["Q96IY4", "CPB2", "Carboxypeptidase B2", 1, 4, "type 2 diabetes mellitus", 0.709], ["P13987", "CD59", "CD59 glycoprotein", 1, 1, "primary CD59 deficiency", 0.705], ["P25311", "AZGP1", "Zinc-alpha-2-glycoprotein", 1, 1, "neoplasm", 0.701], ["Q12884", "FAP", "Prolyl endopeptidase FAP", 1, 7, "psoriasis", 0.7], ["P07225", "PROS1", "Vitamin K-dependent protein S", 1, 2, "thrombophilia due to protein S deficiency, autosomal dominant", 0.7], ["P00746", "CFD", "Complement factor D", 1, 4, "recurrent Neisseria infections due to factor D deficiency", 0.695], ["P00738", "HP", "Haptoglobin", 1, 76, "Hypercholesterolemia", 0.695], ["P19021", "PAM", "Peptidyl-glycine alpha-amidating monooxygenase", 1, 25, "type 2 diabetes mellitus", 0.695], ["P21359", "NF1", "Neurofibromin", 1, 2, "neurofibromatosis type 1", 0.695], ["O95858", "TSPAN15", "Tetraspanin-15", 1, 1, "venous thromboembolism", 0.692], ["P00451", "F8", "Coagulation factor VIII", 1, 13, "hemophilia A", 0.691], ["P10586", "PTPRF", "Receptor-type tyrosine-protein phosphatase F", 1, 4, "smoking initiation", 0.69], ["P50148", "GNAQ", "Guanine nucleotide-binding protein G(q) subunit alpha", 1, 1, "Sturge-Weber syndrome", 0.685], ["P22303", "ACHE", "Acetylcholinesterase", 1, 135, "Alzheimer disease", 0.685], ["P03950", "ANG", "Angiogenin", 1, 99, "amyotrophic lateral sclerosis", 0.685], ["P01008", "SERPINC1", "Antithrombin-III", 1, 11, "hereditary antithrombin deficiency", 0.685], ["O00501", "CLDN5", "Claudin-5", 1, 1, "genetic disorder", 0.685], ["Q15485", "FCN2", "Ficolin-2", 1, 2, "hypopituitarism", 0.682], ["Q07954", "LRP1", "Prolow-density lipoprotein receptor-related protein 1", 1, 3, "developmental dysplasia of the hip", 0.682], ["P00918", "CA2", "Carbonic anhydrase 2", 1, 109, "Osteopetrosis with renal tubular acidosis", 0.68], ["P13501", "CCL5", "C-C motif chemokine 5", 1, 6, "neoplasm", 0.68], ["P09958", "FURIN", "Furin", 1, 4, "coronary artery disease", 0.68], ["P61073", "CXCR4", "C-X-C chemokine receptor type 4", 1, 17, "WHIM syndrome", 0.68], ["P12259", "F5", "Coagulation factor V", 1, 4, "thrombophilia due to activated protein C resistance", 0.68], ["P14384", "CPM", "Carboxypeptidase M", 1, 3, "hydronephrosis", 0.68], ["P09382", "LGALS1", "Galectin-1", 1, 6, "glaucoma", 0.675], ["P49913", "CAMP", "Cathelicidin antimicrobial peptide", 1, 30, "prostate carcinoma", 0.675], ["P09758", "TACSTD2", "Tumor-associated calcium signal transducer 2", 1, 4, "gelatinous drop-like corneal dystrophy", 0.673], ["P98066", "TNFAIP6", "Tumor necrosis factor-inducible gene 6 protein", 1, 1, "type 2 diabetes mellitus", 0.671], ["P25942", "CD40", "Tumor necrosis factor receptor superfamily member 5", 1, 8, "hyper-IgM syndrome type 3", 0.67], ["P08581", "MET", "Hepatocyte growth factor receptor", 1, 149, "papillary renal cell carcinoma", 0.669], ["P56817", "BACE1", "Beta-secretase 1", 1, 9, "metabolic disease", 0.668], ["P08311", "CTSG", "Cathepsin G", 1, 6, "tuberculosis", 0.667], ["P01137", "TGFB1", "Transforming growth factor beta-1 proprotein", 1, 4, "Camurati-Engelmann disease", 0.665], ["Q9Y251", "HPSE", "Heparanase", 1, 7, "Vitiligo", 0.66], ["Q13093", "PLA2G7", "Platelet-activating factor acetylhydrolase", 1, 1, "Platelet-activating factor acetylhydrolase deficiency", 0.66], ["P15151", "PVR", "Poliovirus receptor", 1, 3, "Alzheimer disease", 0.66], ["P16870", "CPE", "Carboxypeptidase E", 1, 16, "BDV syndrome", 0.66], ["P98155", "VLDLR", "Very low-density lipoprotein receptor", 1, 1, "Dysequilibrium syndrome", 0.66], ["P22692", "IGFBP4", "Insulin-like growth factor-binding protein 4", 1, 6, "allergic rhinitis", 0.66], ["Q13433", "SLC39A6", "Zinc transporter ZIP6", 1, 1, "breast cancer", 0.66], ["P03952", "KLKB1", "Plasma kallikrein", 1, 6, "inherited prekallikrein deficiency", 0.656], ["P02461", "COL3A1", "Collagen alpha-1(III) chain", 1, 1, "Ehlers-Danlos syndrome, vascular type", 0.656], ["P15907", "ST6GAL1", "Beta-galactoside alpha-2,6-sialyltransferase 1", 1, 1, "COVID-19", 0.655], ["P08709", "F7", "Coagulation factor VII", 1, 4, "factor VII deficiency", 0.655], ["Q9Y625", "GPC6", "Glypican-6", 1, 1, "autosomal recessive omodysplasia", 0.655], ["P02766", "TTR", "Transthyretin", 1, 11, "amyloidosis, hereditary systemic 1", 0.655], ["P37173", "TGFBR2", "TGF-beta receptor type-2", 1, 8, "Loeys-Dietz syndrome", 0.654], ["Q9H0R3", "TMEM222", "Transmembrane protein 222", 1, 3, "neurodevelopmental disorder with motor and speech delay and behavioral abnormalities", 0.654], ["P36894", "BMPR1A", "Bone morphogenetic protein receptor type-1A", 1, 1, "juvenile polyposis syndrome", 0.653], ["P02724", "GYPA", "Glycophorin-A", 1, 1, "malaria", 0.653], ["P62937", "PPIA", "Peptidyl-prolyl cis-trans isomerase A", 1, 1, "HIV infection", 0.652], ["P60033", "CD81", "CD81 antigen", 1, 5, "immunodeficiency, common variable, 6", 0.652], ["P46531", "NOTCH1", "Neurogenic locus notch homolog protein 1", 1, 4, "Adams-Oliver syndrome", 0.652], ["P16234", "PDGFRA", "Platelet-derived growth factor receptor alpha", 1, 4, "gastrointestinal stromal tumor", 0.652], ["P32942", "ICAM3", "Intercellular adhesion molecule 3", 1, 3, "lymphatic system disease", 0.648], ["P09104", "ENO2", "Gamma-enolase", 1, 1, "neurodegenerative disease", 0.645], ["P07237", "P4HB", "Protein disulfide-isomerase", 1, 2, "Cole-Carpenter syndrome", 0.644], ["P29323", "EPHB2", "Ephrin type-B receptor 2", 1, 1, "medullary thyroid gland carcinoma", 0.643], ["P01344", "IGF2", "Insulin-like growth factor 2", 1, 13, "Silver-Russell syndrome", 0.643], ["P48740", "MASP1", "Mannan-binding lectin serine protease 1", 1, 2, "3MC syndrome 1", 0.64], ["Q14242", "SELPLG", "P-selectin glycoprotein ligand 1", 1, 1, "glaucoma", 0.64], ["P06702", "S100A9", "Protein S100-A9", 1, 9, "inborn error of immunity", 0.637], ["P08519", "LPA", "Apolipoprotein(a)", 1, 8, "cardiovascular disease", 0.637], ["P05109", "S100A8", "Protein S100-A8", 1, 5, "inborn error of immunity", 0.635], ["P01732", "CD8A", "T-cell surface glycoprotein CD8 alpha chain", 1, 2, "progressive supranuclear palsy", 0.635], ["P01009", "SERPINA1", "Alpha-1-antitrypsin", 1, 12, "Alpha-1-antitrypsin deficiency", 0.631], ["P02647", "APOA1", "Apolipoprotein A-I", 1, 10, "hypoalphalipoproteinemia, primary, 2", 0.63], ["P50281", "MMP14", "Matrix metalloproteinase-14", 1, 10, "Torg-Winchester syndrome", 0.63], ["P02788", "LTF", "Lactotransferrin", 1, 3, "tuberculosis", 0.625], ["P51884", "LUM", "Lumican", 1, 7, "lumbar disc herniation", 0.625], ["O75976", "CPD", "Carboxypeptidase D", 1, 1, "neurodegenerative disease", 0.625], ["P49862", "KLK7", "Kallikrein-7", 1, 1, "neurodegenerative disease", 0.624], ["P21926", "CD9", "CD9 antigen", 1, 17, "diphtheria", 0.623], ["P21796", "VDAC1", "Non-selective voltage-gated ion channel VDAC1", 1, 1, "neurodegenerative disease", 0.621], ["Q9UNQ0", "ABCG2", "Broad substrate specificity ATP-binding cassette transporter ABCG2", 1, 8, "gout", 0.62], ["P01860", "IGHG3", "Immunoglobulin heavy constant gamma 3", 1, 1, null, 0.62], ["P00749", "PLAU", "Urokinase-type plasminogen activator", 1, 15, "Quebec platelet disorder", 0.62], ["P16671", "CD36", "Platelet glycoprotein 4", 1, 6, "platelet-type bleeding disorder 10", 0.62], ["P11279", "LAMP1", "Lysosome-associated membrane glycoprotein 1", 1, 1, "thrombophilia", 0.619], ["Q14623", "IHH", "Indian hedgehog protein", 1, 1, "brachydactyly type A1", 0.619], ["O14786", "NRP1", "Neuropilin-1", 1, 10, "COVID-19", 0.619], ["Q9ULC3", "RAB23", "Ras-related protein Rab-23", 1, 1, "RAB23-related Carpenter syndrome", 0.619], ["P10451", "SPP1", "Osteopontin", 1, 62, "osteoporosis", 0.615], ["P01876", "IGHA1", "Immunoglobulin heavy constant alpha 1", 1, 2, "IGA glomerulonephritis", 0.612], ["P02774", "GC", "Vitamin D-binding protein", 1, 295, "vitamin D deficiency", 0.61], ["P17693", "HLA-G", "HLA class I histocompatibility antigen, alpha chain G", 1, 2, "COVID-19", 0.61], ["P01871", "IGHM", "Immunoglobulin heavy constant mu", 1, 3, "agammaglobulinemia", 0.61], ["P01011", "SERPINA3", "Alpha-1-antichymotrypsin", 1, 4, "prostate carcinoma", 0.61], ["P13612", "ITGA4", "Integrin alpha-4", 1, 3, "Crohn's disease", 0.61], ["P00740", "F9", "Coagulation factor IX", 1, 8, "hemophilia B", 0.61], ["O43866", "CD5L", "CD5 antigen-like", 1, 3, "functional neutrophil defect", 0.61], ["O75487", "GPC4", "Glypican-4", 1, 1, "Keipert syndrome", 0.61], ["P23368", "ME2", "NAD-dependent malic enzyme, mitochondrial", 1, 2, "diabetes mellitus", 0.61], ["Q12891", "HYAL2", "Hyaluronidase-2", 1, 1, "Muggenthaler-Chowdhury-Chioza syndrome", 0.61], ["P31025", "LCN1", "Lipocalin-1", 1, 6, "cervical carcinoma", 0.609], ["P00450", "CP", "Ceruloplasmin", 1, 130, "aceruloplasminemia", 0.608], ["P05362", "ICAM1", "Intercellular adhesion molecule 1", 1, 43, "neurodegenerative disease", 0.608], ["P15529", "CD46", "Membrane cofactor protein", 1, 9, "atypical hemolytic-uremic syndrome with MCP/CD46 anomaly", 0.608], ["P55157", "MTTP", "Microsomal triglyceride transfer protein large subunit", 1, 1, "abetalipoproteinemia", 0.608], ["O75508", "CLDN11", "Claudin-11", 1, 1, "leukodystrophy, hypomyelinating, 22", 0.608], ["P03956", "MMP1", "Interstitial collagenase", 1, 5, "acne", 0.605], ["P11166", "SLC2A1", "Solute carrier family 2, facilitated glucose transporter member 1", 1, 2, "encephalopathy due to GLUT1 deficiency", 0.605], ["P01034", "CST3", "Cystatin-C", 1, 13, "Hereditary cerebral hemorrhage with amyloidosis", 0.605], ["Q9NZQ7", "CD274", "Programmed cell death 1 ligand 1", 1, 67, "non-small cell lung carcinoma", 0.605], ["P00736", "C1R", "Complement C1r subcomponent", 1, 2, null, 0.605], ["P36897", "TGFBR1", "TGF-beta receptor type-1", 1, 1, "Loeys-Dietz syndrome 1", 0.605], ["P27918", "CFP", "Properdin", 1, 18, "Properdin deficiency", 0.605], ["P01023", "A2M", "Alpha-2-macroglobulin", 1, 2, "refractive error", 0.605], ["P00742", "F10", "Coagulation factor X", 1, 8, "factor X deficiency", 0.605], ["P10646", "TFPI", "Tissue factor pathway inhibitor", 1, 28, "hemophilia A", 0.605], ["P10909", "CLU", "Clusterin", 1, 5, "Alzheimer disease", 0.605], ["P01031", "C5", "Complement C5", 1, 58, "Immunodeficiency due to a late component of complements deficiency", 0.605], ["P18615", "NELFE", "Negative elongation factor E", 1, 4, "HIV infection", 0.605], ["P26006", "ITGA3", "Integrin alpha-3", 1, 1, "epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome", 0.605], ["P46734", "MAP2K3", "Dual specificity mitogen-activated protein kinase kinase 3", 1, 1, "neurodegenerative disease", 0.605], ["P11597", "CETP", "Cholesteryl ester transfer protein", 1, 1, "cholesterol-ester transfer protein deficiency", 0.602], ["Q01650", "SLC7A5", "Large neutral amino acids transporter small subunit 1", 1, 1, "vertebral joint disease", 0.602], ["Q16270", "IGFBP7", "Insulin-like growth factor-binding protein 7", 1, 4, "familial retinal arterial macroaneurysm", 0.602], ["Q99538", "LGMN", "Legumain", 1, 2, "crush injury", 0.6], ["P01375", "TNF", "Tumor necrosis factor", 1, 260, null, 0.6], ["Q13332", "PTPRS", "Receptor-type tyrosine-protein phosphatase S", 1, 1, "atrial fibrillation", 0.6], ["P04626", "ERBB2", "Receptor tyrosine-protein kinase erbB-2", 1, 119, "non-small cell lung carcinoma", 0.6], ["P46821", "MAP1B", "Microtubule-associated protein 1B", 1, 5, "periventricular nodular heterotopia 9", 0.6], ["P43235", "CTSK", "Cathepsin K", 1, 3, "pycnodysostosis", 0.595], ["P29965", "CD40LG", "CD40 ligand", 1, 6, "hyper-IgM syndrome type 1", 0.595], ["P30046", "DDT", "D-dopachrome decarboxylase", 1, 20, "neurodegenerative disease", 0.594], ["Q7Z3B1", "NEGR1", "Neuronal growth regulator 1", 1, 1, "intelligence", 0.594], ["P55145", "MANF", "Mesencephalic astrocyte-derived neurotrophic factor", 1, 1, "diabetes, deafness, developmental delay, and short stature syndrome", 0.594], ["P37802", "TAGLN2", "Transgelin-2", 1, 3, "neurodegenerative disease", 0.593], ["Q15438", "CYTH1", "Cytohesin-1", 1, 6, "type 2 diabetes mellitus", 0.591], ["P19022", "CDH2", "Cadherin-2", 1, 1, "agenesis of corpus callosum, cardiac, ocular, and genital syndrome", 0.59], ["Q14515", "SPARCL1", "SPARC-like protein 1", 1, 2, "gout", 0.589], ["P02787", "TF", "Serotransferrin", 1, 114, "atransferrinemia", 0.587], ["P02786", "TFRC", "Transferrin receptor protein 1", 1, 3, "TFRC-related combined immunodeficiency", 0.587], ["P05121", "SERPINE1", "Plasminogen activator inhibitor 1", 1, 25, "congenital plasminogen activator inhibitor type 1 deficiency", 0.585], ["P31948", "STIP1", "Stress-induced-phosphoprotein 1", 1, 7, "neurodegenerative disease", 0.585], ["P13497", "BMP1", "Bone morphogenetic protein 1", 1, 1, "osteogenesis imperfecta", 0.585], ["P02458", "COL2A1", "Collagen alpha-1(II) chain", 1, 1, "spondyloepiphyseal dysplasia congenita", 0.583], ["Q15796", "SMAD2", "SMAD family member 2", 1, 7, "Loeys-Dietz syndrome 6", 0.583], ["Q15813", "TBCE", "Tubulin-specific chaperone E", 1, 1, "hypoparathyroidism-retardation-dysmorphism syndrome", 0.582], ["Q13287", "NMI", "N-myc-interactor", 1, 2, "type 2 diabetes mellitus", 0.581], ["P07355", "ANXA2", "Annexin A2", 1, 12, "neurodegenerative disease", 0.58], ["P28907", "CD38", "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1", 1, 5, "multiple myeloma", 0.58], ["Q9H244", "P2RY12", "P2Y purinoceptor 12", 1, 2, "platelet-type bleeding disorder 8", 0.58], ["Q13724", "MOGS", "Mannosyl-oligosaccharide glucosidase", 1, 3, "MOGS-congenital disorder of glycosylation", 0.58], ["O95445", "APOM", "Apolipoprotein M", 1, 10, "type 2 diabetes mellitus", 0.58], ["P12036", "NEFH", "Neurofilament heavy polypeptide", 1, 2, "Charcot-Marie-Tooth disease axonal type 2CC", 0.579], ["P43652", "AFM", "Afamin", 1, 181, "Abnormality of the skeletal system", 0.575], ["P11802", "CDK4", "Cyclin-dependent kinase 4", 1, 2, "melanoma, cutaneous malignant, susceptibility to, 3", 0.575], ["P23508", "MCC", "Colorectal mutant cancer protein", 1, 3, "colon carcinoma", 0.575], ["O15327", "INPP4B", "Inositol polyphosphate 4-phosphatase type II", 1, 2, "neurodegenerative disease", 0.574], ["P24394", "IL4R", "Interleukin-4 receptor subunit alpha", 1, 3, "asthma", 0.574], ["P07550", "ADRB2", "Beta-2 adrenergic receptor", 1, 2, "asthma", 0.573], ["Q9UPY5", "SLC7A11", "Cystine/glutamate transporter", 1, 5, "schizophrenia", 0.573], ["P06756", "ITGAV", "Integrin alpha-V", 1, 8, "neurodegenerative disease", 0.572], ["P14174", "MIF", "Macrophage migration inhibitory factor", 1, 2, "rheumatoid arthritis", 0.57], ["O43854", "EDIL3", "EGF-like repeat and discoidin I-like domain-containing protein 3", 1, 1, "COVID-19", 0.57], ["P00750", "PLAT", "Tissue-type plasminogen activator", 1, 9, "stroke", 0.57], ["P00813", "ADA", "Adenosine deaminase", 1, 72, "Severe combined immunodeficiency due to adenosine deaminase deficiency", 0.57], ["P02654", "APOC1", "Apolipoprotein C-I", 1, 4, null, 0.57], ["P26599", "PTBP1", "Polypyrimidine tract-binding protein 1", 1, 2, "dengue disease", 0.567], ["P27487", "DPP4", "Dipeptidyl peptidase 4", 1, 4, "type 2 diabetes mellitus", 0.565], ["P00747", "PLG", "Plasminogen", 1, 51, "hypoplasminogenemia", 0.565], ["P12273", "PIP", "Prolactin-inducible protein", 1, 7, "neurodegenerative disease", 0.564], ["Q07352", "ZFP36L1", "mRNA decay activator protein ZFP36L1", 1, 1, "neurodegenerative disease", 0.564], ["P30519", "HMOX2", "Heme oxygenase 2", 1, 1, "neuroinflammatory disorder", 0.563], ["P11274", "BCR", "Breakpoint cluster region protein", 1, 20, "chronic myelogenous leukemia", 0.562], ["P18206", "VCL", "Vinculin", 1, 4, "hypertrophic cardiomyopathy", 0.56], ["Q0VDF9", "HSPA14", "Heat shock 70 kDa protein 14", 1, 1, "neurodegenerative disease", 0.56], ["Q03393", "PTS", "6-pyruvoyl tetrahydrobiopterin synthase", 1, 16, null, 0.56], ["O75084", "FZD7", "Frizzled-7", 1, 2, "Abnormality of the skeletal system", 0.556], ["Q92743", "HTRA1", "Serine protease HTRA1", 1, 1, "cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2", 0.556], ["P12821", "ACE", "Angiotensin-converting enzyme", 1, 108, "diabetic nephropathy", 0.555], ["P08253", "MMP2", "72 kDa type IV collagenase", 1, 20, "Torg-Winchester syndrome", 0.555], ["P02452", "COL1A1", "Collagen alpha-1(I) chain", 1, 3, "osteogenesis imperfecta type 2", 0.555], ["Q5ZPR3", "CD276", "CD276 antigen", 1, 1, "response to statin", 0.555], ["P07947", "YES1", "Tyrosine-protein kinase Yes", 1, 1, "chronic myelogenous leukemia", 0.554], ["P21589", "NT5E", "5'-nucleotidase", 1, 3, "hereditary arterial and articular multiple calcification syndrome", 0.552], ["Q29983", "MICA", "MHC class I polypeptide-related sequence A", 1, 7, null, 0.55], ["P32119", "PRDX2", "Peroxiredoxin-2", 1, 2, "neurodegenerative disease", 0.55], ["P02753", "RBP4", "Retinol-binding protein 4", 1, 16, "progressive retinal dystrophy due to retinol transport defect", 0.549], ["P09172", "DBH", "Dopamine beta-hydroxylase", 1, 2, "orthostatic hypotension 1", 0.547], ["P14735", "IDE", "Insulin-degrading enzyme", 1, 27, "type 2 diabetes mellitus", 0.545], ["Q08722", "CD47", "Leukocyte surface antigen CD47", 1, 11, "myelodysplastic syndrome", 0.545], ["P42858", "HTT", "Huntingtin", 1, 18, "Huntington disease", 0.545], ["O75324", "SNN", "Stannin", 1, 1, "cardiomyopathy", 0.545], ["P10145", "CXCL8", "Interleukin-8", 1, 15, "coronary artery disease", 0.545], ["P35443", "THBS4", "Thrombospondin-4", 1, 3, "Abnormality of the skeletal system", 0.545], ["Q9P121", "NTM", "Neurotrimin", 1, 2, "smoking initiation", 0.541], ["P10599", "TXN", "Thioredoxin", 1, 28, "neurodegenerative disease", 0.54], ["O43493", "TGOLN2", "Trans-Golgi network integral membrane protein 2", 1, 1, "osteoporosis", 0.54], ["P32856", "STX2", "Syntaxin-2", 1, 7, "venous thromboembolism", 0.54], ["P36955", "SERPINF1", "Pigment epithelium-derived factor", 1, 17, "osteogenesis imperfecta", 0.54], ["P25774", "CTSS", "Cathepsin S", 1, 11, "basal cell carcinoma", 0.538], ["P14136", "GFAP", "Glial fibrillary acidic protein", 1, 4, "Alexander disease", 0.537], ["P16150", "SPN", "Leukosialin", 1, 1, "neurodegenerative disease", 0.533], ["Q13794", "PMAIP1", "Phorbol-12-myristate-13-acetate-induced protein 1", 1, 1, "neurodegenerative disease", 0.533], ["P80162", "CXCL6", "C-X-C motif chemokine 6", 1, 3, "neurodegenerative disease", 0.533], ["P56199", "ITGA1", "Integrin alpha-1", 1, 1, "type 2 diabetes mellitus", 0.531], ["P21980", "TGM2", "Protein-glutamine gamma-glutamyltransferase 2", 1, 1, "neurodegenerative disease", 0.529], ["P05154", "SERPINA5", "Plasma serine protease inhibitor", 1, 2, "preeclampsia", 0.529], ["P01308", "INS", "Insulin", 1, 243, "diabetes mellitus, permanent neonatal 4", 0.528], ["A6XGL2", "INS", "Insulin", 1, 243, "diabetes mellitus, permanent neonatal 4", 0.528], ["Q9H082", "RAB33B", "Ras-related protein Rab-33B", 1, 3, "Smith-McCort dysplasia 2", 0.527], ["P43490", "NAMPT", "Nicotinamide phosphoribosyltransferase", 1, 5, "neurodegenerative disease", 0.525], ["P17405", "SMPD1", "Sphingomyelin phosphodiesterase", 1, 1, "Niemann-Pick disease type A", 0.525], ["P13726", "F3", "Tissue factor", 1, 36, "cervical cancer", 0.525], ["P14780", "MMP9", "Matrix metalloproteinase-9", 1, 69, "metaphyseal anadysplasia", 0.525], ["P13591", "NCAM1", "Neural cell adhesion molecule 1", 1, 1, "smoking initiation", 0.525], ["P06744", "GPI", "Glucose-6-phosphate isomerase", 1, 19, "hemolytic anemia due to glucophosphate isomerase deficiency", 0.523], ["P09871", "C1S", "Complement C1s subcomponent", 1, 1, "Ehlers-Danlos syndrome, periodontal type 2", 0.52], ["Q07108", "CD69", "Early activation antigen CD69", 1, 5, "hypothyroidism", 0.52], ["P13688", "CEACAM1", "Cell adhesion molecule CEACAM1", 1, 1, "neoplasm", 0.52], ["P08637", "FCGR3A", "Low affinity immunoglobulin gamma Fc region receptor III-A", 1, 2, "autosomal recessive primary immunodeficiency with defective spontaneous natural killer cell cytotoxicity", 0.52], ["P0CG30", "GSTT2B", "Glutathione S-transferase theta-2B", 1, 26, "neurodegenerative disease", 0.517], ["O75594", "PGLYRP1", "Peptidoglycan recognition protein 1", 1, 2, "dementia", 0.516], ["Q96RS0", "TGS1", "Trimethylguanosine synthase", 1, 1, "neurodegenerative disease", 0.514], ["P26583", "HMGB2", "High mobility group protein B2", 1, 1, "neoplasm", 0.511], ["Q02161", "RHD", "Blood group Rh(D) polypeptide", 1, 4, "Rh deficiency syndrome", 0.508], ["P99999", "CYCS", "Cytochrome c", 1, 79, "thrombocytopenia 4", 0.505], ["P26440", "IVD", "Isovaleryl-CoA dehydrogenase, mitochondrial", 1, 2, "isovaleric acidemia", 0.505], ["P41217", "CD200", "OX-2 membrane glycoprotein", 1, 4, "basal cell carcinoma", 0.505], ["P43251", "BTD", "Biotinidase", 1, 1, "biotinidase deficiency", 0.504], ["O15067", "PFAS", "Phosphoribosylformylglycinamidine synthase", 1, 10, "dyskeratosis congenita", 0.502], ["O60784", "TOM1", "Target of Myb1 membrane trafficking protein", 1, 1, "neurodegenerative disease", 0.502], ["Q8NF50", "DOCK8", "Dedicator of cytokinesis protein 8", 1, 2, "combined immunodeficiency due to DOCK8 deficiency", 0.501], ["P60763", "RAC3", "Ras-related C3 botulinum toxin substrate 3", 1, 1, "neurodevelopmental disorder with structural brain anomalies and dysmorphic facies", 0.5], ["Q15828", "CST6", "Cystatin-M", 1, 1, "autosomal recessive hypohidrotic ectodermal dysplasia", 0.5], ["P50895", "BCAM", "Basal cell adhesion molecule", 1, 2, "metabolic syndrome", 0.5], ["O75781", "PALM", "Paralemmin-1", 1, 12, "Anxiety", 0.5], ["Q9UHD9", "UBQLN2", "Ubiquilin-2", 1, 2, "amyotrophic lateral sclerosis type 15", 0.499], ["Q8NHS0", "DNAJB8", "DnaJ homolog subfamily B member 8", 1, 2, "neurodegenerative disease", 0.497], ["P50461", "CSRP3", "Cysteine and glycine-rich protein 3", 1, 1, "dilated cardiomyopathy 1M", 0.496], ["P01730", "CD4", "T-cell surface glycoprotein CD4", 1, 96, "HIV infection", 0.495], ["P52926", "HMGA2", "High mobility group protein HMGI-C", 1, 5, "Silver-Russell syndrome 5", 0.494], ["P52594", "AGFG1", "Arf-GAP domain and FG repeat-containing protein 1", 1, 1, "nervous system benign neoplasm", 0.494], ["Q9NXG6", "P4HTM", "Transmembrane prolyl 4-hydroxylase", 1, 1, "hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities", 0.492], ["Q12979", "ABR", "Active breakpoint cluster region-related protein", 1, 3, "systemic lupus erythematosus", 0.491], ["Q8NB16", "MLKL", "Mixed lineage kinase domain-like protein", 1, 5, "chronic recurrent multifocal osteomyelitis", 0.49], ["P12830", "CDH1", "Cadherin-1", 1, 4, "CDH1-related diffuse gastric and lobular breast cancer syndrome", 0.49], ["P35241", "RDX", "Radixin", 1, 2, "hearing loss, autosomal recessive", 0.49], ["P08842", "STS", "Steryl-sulfatase", 1, 5, null, 0.49], ["P07998", "RNASE1", "Ribonuclease pancreatic", 1, 17, "neoplasm", 0.485], ["Q86WV6", "STING1", "Stimulator of interferon genes protein", 1, 10, "STING-associated vasculopathy with onset in infancy", 0.485], ["P23458", "JAK1", "Tyrosine-protein kinase JAK1", 1, 2, "rheumatoid arthritis", 0.485], ["P63098", "PPP3R1", "Calcineurin subunit B type 1", 1, 2, "Abnormality of the skeletal system", 0.485], ["P35354", "PTGS2", "Prostaglandin G/H synthase 2", 1, 7, "rheumatoid arthritis", 0.483], ["P80188", "LCN2", "Neutrophil gelatinase-associated lipocalin", 1, 25, "psoriasis", 0.482], ["Q53GL0", "PLEKHO1", "Pleckstrin homology domain-containing family O member 1", 1, 2, "neurodegenerative disease", 0.482], ["Q99733", "NAP1L4", "Nucleosome assembly protein 1-like 4", 1, 1, "neurodegenerative disease", 0.48], ["Q4LDE5", "SVEP1", "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", 1, 9, "hypertension", 0.48], ["Q9BVI4", "NOC4L", "Nucleolar complex protein 4 homolog", 1, 1, "Alzheimer disease", 0.478], ["Q01518", "CAP1", "Adenylyl cyclase-associated protein 1", 1, 1, "neurodegenerative disease", 0.476], ["P50416", "CPT1A", "Carnitine O-palmitoyltransferase 1, liver isoform", 1, 1, "carnitine palmitoyl transferase 1A deficiency", 0.474], ["P08865", "RPSA", "Small ribosomal subunit protein uS2", 1, 1, "familial isolated congenital asplenia", 0.471], ["O00505", "KPNA3", "Importin subunit alpha-4", 1, 1, "spastic paraplegia 88, autosomal dominant", 0.47], ["P09543", "CNP", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", 1, 9, "myopia 2, autosomal dominant", 0.47], ["P53365", "ARFIP2", "Arfaptin-2", 1, 1, "hepatocellular carcinoma", 0.468], ["P20794", "MAK", "Serine/threonine-protein kinase MAK", 1, 3, "retinitis pigmentosa", 0.467], ["P47929", "LGALS7", "Galectin-7", 1, 1, "neurodegenerative disease", 0.465], ["P10643", "C7", "Complement component C7", 1, 14, "Immunodeficiency due to a late component of complements deficiency", 0.465], ["O95487", "SEC24B", "Protein transport protein Sec24B", 1, 1, "atrial heart septal defect", 0.465], ["P35659", "DEK", "Protein DEK", 1, 14, "atrial fibrillation", 0.464], ["P05452", "CLEC3B", "Tetranectin", 1, 1, "macular dystrophy, retinal, 4", 0.46], ["P69905", "HBA1", "Hemoglobin subunit alpha", 1, 30, "hemoglobin H disease", 0.457], ["Q93045", "STMN2", "Stathmin-2", 1, 3, "neurodegenerative disease", 0.457], ["P35625", "TIMP3", "Metalloproteinase inhibitor 3", 1, 3, "Sorsby fundus dystrophy", 0.457], ["P40121", "CAPG", "Macrophage-capping protein", 1, 1, "Sensorineural hearing impairment", 0.455], ["P62745", "RHOB", "Rho-related GTP-binding protein RhoB", 1, 7, "neurodegenerative disease", 0.455], ["Q0PNE2", "ELP6", "Elongator complex protein 6", 1, 3, "Crohn's disease", 0.452], ["Q9Y315", "DERA", "Deoxyribose-phosphate aldolase", 1, 2, "mathematical ability", 0.452], ["Q13308", "PTK7", "Inactive tyrosine-protein kinase 7", 1, 110, "neurodegenerative disease", 0.452], ["Q13443", "ADAM9", "Disintegrin and metalloproteinase domain-containing protein 9", 1, 3, "Cone rod dystrophy", 0.452], ["P02743", "APCS", "Serum amyloid P-component", 1, 13, "AL amyloidosis", 0.45], ["Q5TA50", "CPTP", "Ceramide-1-phosphate transfer protein", 1, 1, "pachyonychia congenita", 0.45], ["P02675", "FGB", "Fibrinogen beta chain", 1, 1, "congenital afibrinogenemia", 0.45], ["Q9GZY8", "MFF", "Mitochondrial fission factor", 1, 2, "Lethal encephalopathy due to mitochondrial and peroxisomal fission defect", 0.45], ["P32121", "ARRB2", "Beta-arrestin-2", 1, 4, "cancer", 0.45], ["Q12905", "ILF2", "Interleukin enhancer-binding factor 2", 1, 2, "neurodegenerative disease", 0.45], ["P08571", "CD14", "Monocyte differentiation antigen CD14", 1, 14, "dengue disease", 0.449], ["Q9P2X3", "IMPACT", "Protein IMPACT", 1, 704, "cancer", 0.448], ["Q99969", "RARRES2", "Retinoic acid receptor responder protein 2", 1, 2, "Abnormality of the skeletal system", 0.445], ["P31947", "SFN", "14-3-3 protein sigma", 1, 2, "neurodegenerative disease", 0.444], ["Q07075", "ENPEP", "Glutamyl aminopeptidase", 1, 2, "hypertension", 0.44], ["P29992", "GNA11", "Guanine nucleotide-binding protein subunit alpha-11", 1, 1, "Familial isolated hypoparathyroidism", 0.44], ["P07858", "CTSB", "Cathepsin B", 1, 8, "Alzheimer disease", 0.44], ["P01848", "TRAC", "T cell receptor alpha chain constant", 1, 8, null, 0.44], ["Q9P126", "CLEC1B", "C-type lectin domain family 1 member B", 1, 1, "hepatocellular carcinoma", 0.44], ["Q8TB72", "PUM2", "Pumilio homolog 2", 1, 1, "neurodegenerative disease", 0.44], ["P16455", "MGMT", "Methylated-DNA--protein-cysteine methyltransferase", 1, 4, "Abnormality of the skeletal system", 0.439], ["Q9P0M6", "MACROH2A2", "Core histone macro-H2A.2", 1, 13, "enteritis", 0.437], ["P24593", "IGFBP5", "Insulin-like growth factor-binding protein 5", 1, 4, "hypothyroidism", 0.432], ["P07996", "THBS1", "Thrombospondin-1", 1, 6, "autism spectrum disorder", 0.429], ["P29317", "EPHA2", "Ephrin type-A receptor 2", 1, 16, "Total congenital cataract", 0.427], ["Q05655", "PRKCD", "Protein kinase C delta type", 1, 2, "autoimmune lymphoproliferative syndrome", 0.427], ["P01037", "CST1", "Cystatin-SN", 1, 1, "alcohol drinking", 0.425], ["P07910", "HNRNPC", "Heterogeneous nuclear ribonucleoproteins C1/C2", 1, 1, "intellectual developmental disorder, autosomal dominant 74", 0.423], ["Q9NRA1", "PDGFC", "Platelet-derived growth factor C", 1, 2, "Abnormality of the skeletal system", 0.422], ["P42704", "LRPPRC", "Leucine-rich PPR motif-containing protein, mitochondrial", 1, 2, "congenital lactic acidosis, Saguenay-Lac-Saint-Jean type", 0.422], ["Q07065", "CKAP4", "Cytoskeleton-associated protein 4", 1, 9, "smoking initiation", 0.421], ["P55058", "PLTP", "Phospholipid transfer protein", 1, 2, "familial hyperlipidemia", 0.421], ["P00480", "OTC", "Ornithine transcarbamylase, mitochondrial", 1, 71, "ornithine carbamoyltransferase deficiency", 0.417], ["Q01105", "SET", "Protein SET", 1, 556, "intellectual disability, autosomal dominant 58", 0.417], ["Q16719", "KYNU", "Kynureninase", 1, 2, "vertebral, cardiac, renal, and limb defects syndrome 2", 0.415], ["Q6FI81", "CIAPIN1", "Anamorsin", 1, 1, "neurodegenerative disease", 0.411], ["P56470", "LGALS4", "Galectin-4", 1, 2, "neurodegenerative disease", 0.41], ["Q96SW2", "CRBN", "Protein cereblon", 1, 1, "multiple myeloma", 0.401], ["P06401", "PGR", "Progesterone receptor", 1, 11, "endometriosis", 0.397], ["P01877", "IGHA2", "Immunoglobulin heavy constant alpha 2", 1, 2, "Chronic mucocutaneous candidosis", 0.389], ["P09769", "FGR", "Tyrosine-protein kinase Fgr", 1, 1, "chronic myelogenous leukemia", 0.389], ["O60506", "SYNCRIP", "Heterogeneous nuclear ribonucleoprotein Q", 1, 1, "SYNCRIP-related neurodevelopmental disorder", 0.388], ["P00441", "SOD1", "Superoxide dismutase [Cu-Zn]", 1, 7, "amyotrophic lateral sclerosis", 0.387], ["P34949", "MPI", "Mannose-6-phosphate isomerase", 1, 2, "MPI-congenital disorder of glycosylation", 0.385], ["Q6R327", "RICTOR", "Rapamycin-insensitive companion of mTOR", 1, 2, "lung carcinoma", 0.38], ["Q8NC44", "RETREG2", "Reticulophagy regulator 2", 1, 6, "cyst", 0.378], ["P08574", "CYC1", "Cytochrome c1, heme protein, mitochondrial", 1, 1, "Isolated CoQ-cytochrome C reductase deficiency", 0.377], ["Q8NBP7", "PCSK9", "Proprotein convertase subtilisin/kexin type 9", 1, 23, "familial hypercholesterolemia", 0.37], ["Q96QZ7", "MAGI1", "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", 1, 1, "cervical carcinoma", 0.364], ["Q13423", "NNT", "NAD(P) transhydrogenase, mitochondrial", 1, 3, "familial glucocorticoid deficiency", 0.364], ["Q13009", "TIAM1", "Rho guanine nucleotide exchange factor TIAM1", 1, 1, "neurodevelopmental disorder with language delay and seizures", 0.362], ["P15559", "NQO1", "NAD(P)H dehydrogenase [quinone] 1", 1, 3, "neurodegenerative disease", 0.354], ["P54578", "USP14", "Ubiquitin carboxyl-terminal hydrolase 14", 1, 3, "Abnormality of the skeletal system", 0.339], ["Q99418", "CYTH2", "Cytohesin-2", 1, 2, "neurodegenerative disease", 0.337], ["P06732", "CKM", "Creatine kinase M-type", 1, 2, "response to statin", 0.335], ["O00748", "CES2", "Cocaine esterase", 1, 2, "neurodegenerative disease", 0.33], ["P15531", "NME1", "Nucleoside diphosphate kinase A", 1, 1, "placenta praevia", 0.328], ["P09914", "IFIT1", "Antiviral innate immune response effector IFIT1", 1, 1, "neurodegenerative disease", 0.328], ["P11532", "DMD", "Dystrophin", 1, 32, "Duchenne muscular dystrophy", 0.327], ["P02686", "MBP", "Myelin basic protein", 1, 21, "alcohol drinking", 0.311], ["P07900", "HSP90AA1", "Heat shock protein HSP 90-alpha", 1, 1, "cancer", 0.304], ["P20042", "EIF2S2", "Eukaryotic translation initiation factor 2 subunit 2", 1, 3, "ovarian dysfunction", 0.3], ["P02771", "AFP", "Alpha-fetoprotein", 1, 195, "Congenital deficiency in alpha-fetoprotein", 0.26], ["P04406", "GAPDH", "Glyceraldehyde-3-phosphate dehydrogenase", 1, 11, "neurodegenerative disease", 0.205], ["Q16798", "ME3", "NADP-dependent malic enzyme, mitochondrial", 1, 1, "open-angle glaucoma", 0.203], ["P61626", "LYZ", "Lysozyme C", 1, 10, "Familial renal amyloidosis", 0.195], ["P02768", "ALB", "Albumin", 1, 428, "hyperthyroxinemia", 0.14], ["P60709", "ACTB", "Actin, cytoplasmic 1", 1, 3, "Baraitser-Winter syndrome 1", 0.06], ["P08670", "VIM", "Vimentin", 1, 50, "dengue disease", 0.0], ["P23526", "AHCY", "Adenosylhomocysteinase", 1, 1, "Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency", 0.0], ["O00244", "ATOX1", "Copper transport protein ATOX1", 1, 1, "neurodegenerative disease", 0.0], ["Q06830", "PRDX1", "Peroxiredoxin-1", 1, 1, "Methylmalonic acidemia with homocystinuria, type cblC", 0.0], ["Q14376", "GALE", "UDP-glucose 4-epimerase", 1, 1, "galactose epimerase deficiency", 0.0], ["P35270", "SPR", "Sepiapterin reductase", 1, 368, "dopa-responsive dystonia due to sepiapterin reductase deficiency", 0.0], ["P52209", "PGD", "6-phosphogluconate dehydrogenase, decarboxylating", 1, 1, "neurodegenerative disease", 0.0], ["P00915", "CA1", "Carbonic anhydrase 1", 1, 2, "altitude sickness", 0.0], ["O00625", "PIR", "Pirin", 1, 1, "COVID-19", 0.0], ["P02792", "FTL", "Ferritin light chain", 1, 1, "hereditary hyperferritinemia with congenital cataracts", 0.0], ["P60174", "TPI1", "Triosephosphate isomerase", 1, 1, "triosephosphate isomerase deficiency", 0.0], ["P05089", "ARG1", "Arginase-1", 1, 2, "Argininemia", 0.0], ["Q99714", "HSD17B10", "3-hydroxyacyl-CoA dehydrogenase type-2", 1, 1, "HSD10 mitochondrial disease", 0.0], ["P04424", "ASL", "Argininosuccinate lyase", 1, 7, "argininosuccinic aciduria", 0.0], ["P09960", "LTA4H", "Leukotriene A-4 hydrolase", 1, 1, "small intestine neuroendocrine tumor", 0.0], ["P39023", "RPL3", "Large ribosomal subunit protein uL3", 1, 1, "influenza", 0.0], ["P42330", "AKR1C3", "Aldo-keto reductase family 1 member C3", 1, 1, "prostate cancer", 0.0], ["P82921", "MRPS21", "Small ribosomal subunit protein bS21m", 1, 9, "neurodegenerative disease", 0.0], ["P38117", "ETFB", "Electron transfer flavoprotein subunit beta", 1, 4, "multiple acyl-CoA dehydrogenase deficiency", 0.0], ["P04040", "CAT", "Catalase", 1, 123, "acatalasia", 0.0], ["P08758", "ANXA5", "Annexin A5", 1, 2, "habitual abortion", 0.0], ["P31153", "MAT2A", "S-adenosylmethionine synthase isoform type-2", 1, 1, "neurodegenerative disease", 0.0], ["P05091", "ALDH2", "Aldehyde dehydrogenase, mitochondrial", 1, 1, "alcohol dependence", 0.0], ["P05413", "FABP3", "Fatty acid-binding protein, heart", 1, 2, "early-onset non-syndromic cataract", 0.0], ["P00374", "DHFR", "Dihydrofolate reductase", 1, 6, "constitutional megaloblastic anemia with severe neurologic disease", 0.0], ["Q96GD0", "PDXP", "Chronophin", 1, 1, "experimental autoimmune encephalomyelitis", 0.0], ["P27338", "MAOB", "Amine oxidase [flavin-containing] B", 1, 1, "Parkinson disease", 0.0], ["P68036", "UBE2L3", "Ubiquitin-conjugating enzyme E2 L3", 1, 1, "neurodegenerative disease", 0.0], ["P15090", "FABP4", "Fatty acid-binding protein, adipocyte", 1, 1, "type 2 diabetes mellitus", 0.0], ["P32754", "HPD", "4-hydroxyphenylpyruvate dioxygenase", 1, 2, "Tyrosinemia type 3", 0.0], ["P61088", "UBE2N", "Ubiquitin-conjugating enzyme E2 N", 1, 1, "ovarian cancer", 0.0], ["O75608", "LYPLA1", "Acyl-protein thioesterase 1", 1, 1, "ovarian neoplasm", 0.0], ["P02794", "FTH1", "Ferritin heavy chain", 1, 2, "neurodegeneration with brain iron accumulation 9", 0.0], ["P78417", "GSTO1", "Glutathione S-transferase omega-1", 1, 2, "neurodegenerative disease", 0.0], ["P84098", "RPL19", "Large ribosomal subunit protein eL19", 1, 2, "influenza", 0.0], ["P52788", "SMS", "Spermine synthase", 1, 3, "syndromic X-linked intellectual disability Snyder type", 0.0], ["P25787", "PSMA2", "Proteasome subunit alpha type-2", 1, 2, "multiple myeloma", 0.0], ["P55769", "SNU13", "NHP2-like protein 1", 1, 2, "atrial fibrillation", 0.0], ["Q9NPE3", "NOP10", "H/ACA ribonucleoprotein complex subunit 3", 1, 1, "dyskeratosis congenita, autosomal recessive 1", 0.0], ["P06280", "GLA", "Alpha-galactosidase A", 1, 15, "Fabry disease", 0.0], ["P11413", "G6PD", "Glucose-6-phosphate 1-dehydrogenase", 1, 3, "anemia, nonspherocytic hemolytic, due to G6PD deficiency", 0.0], ["P18669", "PGAM1", "Phosphoglycerate mutase 1", 1, 1, "neoplasm", 0.0], ["P10619", "CTSA", "Lysosomal protective protein", 1, 3, "galactosialidosis", 0.0], ["P08133", "ANXA6", "Annexin A6", 1, 1, "systemic lupus erythematosus", 0.0], ["P12004", "PCNA", "DNA sliding clamp PCNA", 1, 13, "ataxia-telangiectasia-like disorder", 0.0], ["P00491", "PNP", "Purine nucleoside phosphorylase", 1, 3, "purine nucleoside phosphorylase deficiency", 0.0], ["P49366", "DHPS", "Deoxyhypusine synthase", 1, 2, "neurodevelopmental disorder with seizures and speech and walking impairment", 0.0], ["P61981", "YWHAG", "14-3-3 protein gamma", 1, 1, "genetic developmental and epileptic encephalopathy", 0.0], ["P04181", "OAT", "Ornithine aminotransferase, mitochondrial", 1, 5, "Gyrate atrophy of choroid and retina", 0.0], ["P04818", "TYMS", "Thymidylate synthase", 1, 4, "dyskeratosis congenita, digenic", 0.0], ["P63104", "YWHAZ", "14-3-3 protein zeta/delta", 1, 2, "neurodegenerative disease", 0.0], ["P63000", "RAC1", "Ras-related C3 botulinum toxin substrate 1", 1, 9, "intellectual disability, autosomal dominant 48", 0.0], ["P19784", "CSNK2A2", "Casein kinase II subunit alpha'", 1, 1, "neurodegenerative disease", 0.0], ["P60953", "CDC42", "Cell division control protein 42 homolog", 1, 3, "macrothrombocytopenia-lymphedema-developmental delay-facial dysmorphism-camptodactyly syndrome", 0.0], ["P61586", "RHOA", "Transforming protein RhoA", 1, 4, "ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies", 0.0], ["P61964", "WDR5", "WD repeat-containing protein 5", 1, 1, "Neurodevelopmental disorder", 0.0], ["P62241", "RPS8", "Small ribosomal subunit protein eS8", 1, 1, "influenza", 0.0], ["Q9NRX2", "MRPL17", "Large ribosomal subunit protein bL17m", 1, 5, "neurodegenerative disease", 0.0], ["P62308", "SNRPG", "Small nuclear ribonucleoprotein G", 1, 5, "neurodegenerative disease", 0.0], ["P01040", "CSTA", "Cystatin-A", 1, 7, "peeling skin syndrome 4", 0.0], ["Q9BYD1", "MRPL13", "Large ribosomal subunit protein uL13m", 1, 1, "neurodegenerative disease", 0.0], ["P04179", "SOD2", "Superoxide dismutase [Mn], mitochondrial", 1, 4, "neurodegenerative disease", 0.0], ["O75223", "GGCT", "Gamma-glutamylcyclotransferase", 1, 1, "ovarian neoplasm", 0.0], ["O15382", "BCAT2", "Branched-chain-amino-acid aminotransferase, mitochondrial", 1, 1, "hypervalinemia and hyperleucine-isoleucinemia", 0.0], ["O14744", "PRMT5", "Protein arginine N-methyltransferase 5", 1, 1, "neurodegenerative disease", 0.0], ["O15294", "OGT", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", 1, 2, "intellectual disability, X-linked 106", 0.0], ["P04062", "GBA1", "Lysosomal acid glucosylceramidase", 1, 1, "Gaucher disease type 1", 0.0], ["P07954", "FH", "Fumarate hydratase, mitochondrial", 1, 4, "hereditary leiomyomatosis and renal cell cancer", 0.0], ["Q9Y2R5", "MRPS17", "Small ribosomal subunit protein uS17m", 1, 9, "neurodegenerative disease", 0.0], ["Q16540", "MRPL23", "Large ribosomal subunit protein uL23m", 1, 5, "neurodegenerative disease", 0.0], ["P62910", "RPL32", "Large ribosomal subunit protein eL32", 1, 1, "influenza", 0.0], ["P42336", "PIK3CA", "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", 1, 2, "megalencephaly-capillary malformation-polymicrogyria syndrome", 0.0], ["P23921", "RRM1", "Ribonucleoside-diphosphate reductase large subunit", 1, 1, "non-small cell lung carcinoma", 0.0], ["Q13084", "MRPL28", "Large ribosomal subunit protein bL28m", 1, 5, "Miyoshi myopathy", 0.0], ["Q15370", "ELOB", "Elongin-B", 1, 1, "HIV infection", 0.0], ["P10253", "GAA", "Lysosomal alpha-glucosidase", 1, 9, "Glycogen storage disease due to acid maltase deficiency", 0.0], ["Q5VW32", "BROX", "BRO1 domain-containing protein BROX", 1, 1, "angina pectoris", 0.0], ["P01111", "NRAS", "GTPase NRas", 1, 2, "Noonan syndrome 6", 0.0], ["Q13347", "EIF3I", "Eukaryotic translation initiation factor 3 subunit I", 1, 1, "neurodegenerative disease", 0.0], ["P23284", "PPIB", "Peptidyl-prolyl cis-trans isomerase B", 1, 3, "osteogenesis imperfecta type 9", 0.0], ["P52789", "HK2", "Hexokinase-2", 1, 5, "neurodegenerative disease", 0.0], ["O14980", "XPO1", "Exportin-1", 1, 2, "multiple myeloma", 0.0], ["Q13526", "PIN1", "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1", 1, 1, "Abnormality of the skeletal system", 0.0], ["P01116", "KRAS", "GTPase KRas", 1, 21, "Noonan syndrome 3", 0.0], ["P07902", "GALT", "Galactose-1-phosphate uridylyltransferase", 1, 1, "classic galactosemia", 0.0], ["A0AVT1", "UBA6", "Ubiquitin-like modifier-activating enzyme 6", 1, 1, "neurodegenerative disease", 0.0], ["Q00535", "CDK5", "Cyclin-dependent kinase 5", 1, 4, "Alzheimer disease", 0.0], ["P00390", "GSR", "Glutathione reductase, mitochondrial", 1, 1, "hemolytic anemia due to glutathione reductase deficiency", 0.0], ["P16435", "POR", "NADPH--cytochrome P450 reductase", 1, 11, "Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis", 0.0], ["F5H747", "UBC", null, 1, 9, "HIV infection", 0.0], ["Q9BYC9", "MRPL20", "Large ribosomal subunit protein bL20m", 1, 5, "neurodegenerative disease", 0.0], ["Q9NYA1", "SPHK1", "Sphingosine kinase 1", 1, 1, "neurodegenerative disease", 0.0], ["P41240", "CSK", "Tyrosine-protein kinase CSK", 1, 1, "cancer", 0.0], ["P62861", "FAU", "Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein", 1, 7, "neurodegenerative disease", 0.0], ["Q9P015", "MRPL15", "Large ribosomal subunit protein uL15m", 1, 5, "neurodegenerative disease", 0.0], ["Q9C0B1", "FTO", "Alpha-ketoglutarate-dependent dioxygenase FTO", 1, 39, "lethal polymalformative syndrome, Boissel type", 0.0], ["Q9Y3D3", "MRPS16", "Small ribosomal subunit protein bS16m", 1, 9, "combined oxidative phosphorylation defect type 2", 0.0], ["P06730", "EIF4E", "Eukaryotic translation initiation factor 4E", 1, 6, "neurodegenerative disease", 0.0], ["O00214", "LGALS8", "Galectin-8", 1, 1, "alcohol drinking", 0.0], ["O15455", "TLR3", "Toll-like receptor 3", 1, 7, "Herpetic encephalitis", 0.0], ["Q9Y5K5", "UCHL5", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", 1, 1, "neurodegenerative disease", 0.0], ["O14773", "TPP1", "Tripeptidyl-peptidase 1", 1, 2, "neuronal ceroid lipofuscinosis 2", 0.0], ["P28482", "MAPK1", "Mitogen-activated protein kinase 1", 1, 9, "Noonan syndrome", 0.0], ["P34947", "GRK5", "G protein-coupled receptor kinase 5", 1, 1, "venous thromboembolism", 0.0], ["P46782", "RPS5", "Small ribosomal subunit protein uS7", 1, 1, "influenza", 0.0], ["Q9NP81", "SARS2", "Serine--tRNA ligase, mitochondrial", 1, 438, "hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome", 0.0], ["P11498", "PC", "Pyruvate carboxylase, mitochondrial", 1, 607, "pyruvate carboxylase deficiency disease", 0.0], ["P27695", "APEX1", "DNA repair nuclease/redox regulator APEX1", 1, 7, "neurodegenerative disease", 0.0], ["P25098", "GRK2", "Beta-adrenergic receptor kinase 1", 1, 5, "Jeune syndrome", 0.0], ["Q9NXA8", "SIRT5", "NAD-dependent protein deacylase sirtuin-5, mitochondrial", 1, 1, "sleep apnea", 0.0], ["Q14195", "DPYSL3", "Dihydropyrimidinase-related protein 3", 1, 2, "neurodegenerative disease", 0.0], ["Q15843", "NEDD8", "Ubiquitin-like protein NEDD8", 1, 1, "neurodegenerative disease", 0.0], ["P35520", "CBS", "Cystathionine beta-synthase", 1, 6, "classic homocystinuria", 0.0], ["P16278", "GLB1", "Beta-galactosidase", 1, 31, "mucopolysaccharidosis type 4B", 0.0], ["P53634", "CTSC", "Dipeptidyl peptidase 1", 1, 1, "Papillon-Lef\u00e8vre syndrome", 0.0], ["Q12933", "TRAF2", "TNF receptor-associated factor 2", 1, 2, "genetic disorder", 0.0], ["Q15369", "ELOC", "Elongin-C", 1, 1, "HIV infection", 0.0], ["P62805", "H4C1", "Histone H4", 1, 5, "infectious disease", 0.0], ["P62068", "USP46", "Ubiquitin carboxyl-terminal hydrolase 46", 1, 1, "male reproductive organ cancer", 0.0], ["P47897", "QARS1", "Glutamine--tRNA ligase", 1, 3, "Diffuse cerebral and cerebellar atrophy-intractable seizures-progressive microcephaly syndrome", 0.0], ["Q16539", "MAPK14", "Mitogen-activated protein kinase 14", 1, 2, "neurodegenerative disease", 0.0], ["Q9UHD2", "TBK1", "Serine/threonine-protein kinase TBK1", 1, 1, "frontotemporal dementia and/or amyotrophic lateral sclerosis 4", 0.0], ["O75844", "ZMPSTE24", "CAAX prenyl protease 1 homolog", 1, 1, "mandibuloacral dysplasia with type B lipodystrophy", 0.0], ["P13639", "EEF2", "Elongation factor 2", 1, 5, "spinocerebellar ataxia type 26", 0.0], ["P39748", "FEN1", "Flap endonuclease 1", 1, 13, "neurodegenerative disease", 0.0], ["P06493", "CDK1", "Cyclin-dependent kinase 1", 1, 3, "neurodegenerative disease", 0.0], ["P32456", "GBP2", "Guanylate-binding protein 2", 1, 2, "bacterial disease", 0.0], ["P06396", "GSN", "Gelsolin", 1, 6, "Finnish type amyloidosis", 0.0], ["O15264", "MAPK13", "Mitogen-activated protein kinase 13", 1, 1, "attention deficit hyperactivity disorder", 0.0], ["P07332", "FES", "Tyrosine-protein kinase Fes/Fps", 1, 6, "hypertension", 0.0], ["Q93034", "CUL5", "Cullin-5", 1, 1, "HIV infection", 0.0], ["P0CG48", "UBC", "Polyubiquitin-C", 1, 9, "HIV infection", 0.0], ["Q96A35", "MRPL24", "Large ribosomal subunit protein uL24m", 1, 5, "neurodegenerative disease", 0.0], ["O14966", "RAB29", "Ras-related protein Rab-29", 1, 3, "prostate carcinoma", 0.0], ["P0DMV8", "HSPA1A", "Heat shock 70 kDa protein 1A", 1, 2, "chronic obstructive pulmonary disease", 0.0], ["P62826", "RAN", "GTP-binding nuclear protein Ran", 1, 46, "HIV infection", 0.0], ["Q99873", "PRMT1", "Protein arginine N-methyltransferase 1", 1, 1, "neurodegenerative disease", 0.0], ["P11142", "HSPA8", "Heat shock cognate 71 kDa protein", 1, 3, "dengue disease", 0.0], ["P24941", "CDK2", "Cyclin-dependent kinase 2", 1, 24, "neurodegenerative disease", 0.0], ["Q9HC16", "APOBEC3G", "DNA dC->dU-editing enzyme APOBEC-3G", 1, 1, "HIV infection", 0.0], ["P49841", "GSK3B", "Glycogen synthase kinase-3 beta", 1, 1, "bipolar disorder", 0.0], ["Q9BRX2", "PELO", "Protein pelota homolog", 1, 1, "type 2 diabetes mellitus", 0.0], ["P16591", "FER", "Tyrosine-protein kinase Fer", 1, 2, "Abnormality of the skeletal system", 0.0], ["P08246", "ELANE", "Neutrophil elastase", 1, 21, "cyclic hematopoiesis", 0.0], ["Q99707", "MTR", "Methionine synthase", 1, 1, "methylcobalamin deficiency type cblG", 0.0], ["P09661", "SNRPA1", "U2 small nuclear ribonucleoprotein A'", 1, 1, "neurodegenerative disease", 0.0], ["Q9HAV4", "XPO5", "Exportin-5", 1, 2, "neurodegenerative disease", 0.0], ["Q8TDX7", "NEK7", "Serine/threonine-protein kinase Nek7", 1, 1, "lymphatic system disease", 0.0], ["Q15257", "PTPA", "Serine/threonine-protein phosphatase 2A activator", 1, 1, "Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development", 0.0], ["O15533", "TAPBP", "Tapasin", 1, 1, null, 0.0], ["P27708", "CAD", "Multifunctional protein CAD", 1, 19, "congenital disorder of glycosylation type I", 0.0], ["Q9Y2R9", "MRPS7", "Small ribosomal subunit protein uS7m", 1, 9, "neurodegenerative disease", 0.0], ["P62081", "RPS7", "Small ribosomal subunit protein eS7", 1, 1, "Blackfan-Diamond anemia", 0.0], ["P50750", "CDK9", "Cyclin-dependent kinase 9", 1, 2, "HIV infection", 0.0], ["O60674", "JAK2", "Tyrosine-protein kinase JAK2", 1, 8, "polycythemia vera", 0.0], ["P15498", "VAV1", "Proto-oncogene vav", 1, 1, "cutaneous Leishmaniasis", 0.0], ["Q92905", "COPS5", "COP9 signalosome complex subunit 5", 1, 1, "Joubert syndrome 21", 0.0], ["P26038", "MSN", "Moesin", 1, 65, "combined immunodeficiency due to moesin deficiency", 0.0], ["O14920", "IKBKB", "Inhibitor of nuclear factor kappa-B kinase subunit beta", 1, 2, "severe combined immunodeficiency due to IKK2 deficiency", 0.0], ["P22830", "FECH", "Ferrochelatase, mitochondrial", 1, 2, "autosomal erythropoietic protoporphyria", 0.0], ["P16104", "H2AX", "Histone H2AX", 1, 6, "cancer", 0.0], ["P84077", "ARF1", "ADP-ribosylation factor 1", 1, 3, "periventricular nodular heterotopia 8", 0.0], ["P42574", "CASP3", "Caspase-3", 1, 71, "neurodegenerative disease", 0.0], ["Q06124", "PTPN11", "Tyrosine-protein phosphatase non-receptor type 11", 1, 1, "Noonan syndrome", 0.0], ["Q07812", "BAX", "Apoptosis regulator BAX", 1, 21, "T-cell acute lymphoblastic leukemia", 0.0], ["P49327", "FASN", "Fatty acid synthase", 1, 1, "dengue disease", 0.0], ["Q08209", "PPP3CA", "Protein phosphatase 3 catalytic subunit alpha", 1, 1, "developmental and epileptic encephalopathy 91", 0.0], ["Q13617", "CUL2", "Cullin-2", 1, 1, "Crohn's disease", 0.0], ["P05771", "PRKCB", "Protein kinase C beta type", 1, 1, "acute myeloid leukemia", 0.0], ["Q6P1L8", "MRPL14", "Large ribosomal subunit protein uL14m", 1, 5, "neurodegenerative disease", 0.0], ["Q92769", "HDAC2", "Histone deacetylase 2", 1, 2, "neoplasm", 0.0], ["Q9NWU5", "MRPL22", "Large ribosomal subunit protein uL22m", 1, 5, "neurodegenerative disease", 0.0], ["Q5T653", "MRPL2", "Large ribosomal subunit protein uL2m", 1, 5, "neurodegenerative disease", 0.0], ["O14727", "APAF1", "Apoptotic protease-activating factor 1", 1, 1, "neurodegenerative disease", 0.0], ["O95786", "RIGI", "Antiviral innate immune response receptor RIG-I", 1, 6, "Singleton-Merten dysplasia", 0.0], ["P42229", "STAT5A", "Signal transducer and activator of transcription 5A", 1, 2, "cancer", 0.0], ["Q00534", "CDK6", "Cyclin-dependent kinase 6", 1, 2, "small cell lung carcinoma", 0.0], ["P06576", "ATP5F1B", "ATP synthase F(1) complex subunit beta, mitochondrial", 1, 1, "hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2", 0.0], ["P41091", "EIF2S3", "Eukaryotic translation initiation factor 2 subunit 3", 1, 3, "MEHMO syndrome", 0.0], ["P35609", "ACTN2", "Alpha-actinin-2", 1, 1, "dilated cardiomyopathy 1AA", 0.0], ["Q9H9Q2", "COPS7B", "COP9 signalosome complex subunit 7b", 1, 1, "head and neck squamous cell carcinoma", 0.0], ["P43403", "ZAP70", "Tyrosine-protein kinase ZAP-70", 1, 4, "combined immunodeficiency due to ZAP70 deficiency", 0.0], ["P30626", "SRI", "Sorcin", 1, 17, "genetic disorder", 0.0], ["Q86VX2", "COMMD7", "COMM domain-containing protein 7", 1, 1, "androgenetic alopecia", 0.0], ["Q06187", "BTK", "Tyrosine-protein kinase BTK", 1, 1, "X-linked agammaglobulinemia", 0.0], ["P52434", "POLR2H", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", 1, 1, "HIV infection", 0.0], ["P08238", "HSP90AB1", "Heat shock protein HSP 90-beta", 1, 1, "multiple myeloma", 0.0], ["P12956", "XRCC6", "DNA repair protein Ku70", 1, 2, "HIV infection", 0.0], ["P35268", "RPL22", "Large ribosomal subunit protein eL22", 1, 1, "influenza", 0.0], ["Q14258", "TRIM25", "E3 ubiquitin/ISG15 ligase TRIM25", 1, 1, "dengue disease", 0.0], ["P43405", "SYK", "Tyrosine-protein kinase SYK", 1, 2, "immunodeficiency 82 with systemic inflammation", 0.0], ["P49406", "MRPL19", "Large ribosomal subunit protein bL19m", 1, 5, "neurodegenerative disease", 0.0], ["Q9GZQ3", "COMMD5", "COMM domain-containing protein 5", 1, 1, "neurodegenerative disease", 0.0], ["Q9Y230", "RUVBL2", "RuvB-like 2", 1, 1, "neurodegenerative disease", 0.0], ["P26196", "DDX6", "Probable ATP-dependent RNA helicase DDX6", 1, 2, "intellectual developmental disorder with impaired language and dysmorphic facies", 0.0], ["Q8NBK3", "SUMF1", "Formylglycine-generating enzyme", 1, 1, "Multiple sulfatase deficiency", 0.0], ["P12931", "SRC", "Proto-oncogene tyrosine-protein kinase Src", 1, 19, "cancer", 0.0], ["Q04837", "SSBP1", "Single-stranded DNA-binding protein, mitochondrial", 1, 1, "optic atrophy 13 with retinal and foveal abnormalities", 0.0], ["P06239", "LCK", "Tyrosine-protein kinase Lck", 1, 3, "severe combined immunodeficiency due to LCK deficiency", 0.0], ["Q9Y3B7", "MRPL11", "Large ribosomal subunit protein uL11m", 1, 5, "neurodegenerative disease", 0.0], ["Q9BYD3", "MRPL4", "Large ribosomal subunit protein uL4m", 1, 5, "neurodegenerative disease", 0.0], ["P84022", "SMAD3", "SMAD family member 3", 1, 6, "Aneurysm - osteoarthritis syndrome", 0.0], ["Q13557", "CAMK2D", "Calcium/calmodulin-dependent protein kinase type II subunit delta", 1, 1, "Neurodevelopmental disorder", 0.0], ["Q9UNP9", "PPIE", "Peptidyl-prolyl cis-trans isomerase E", 1, 1, "dengue disease", 0.0], ["P27986", "PIK3R1", "Phosphatidylinositol 3-kinase regulatory subunit alpha", 1, 1, "SHORT syndrome", 0.0], ["Q02750", "MAP2K1", "Dual specificity mitogen-activated protein kinase kinase 1", 1, 1, "cardiofaciocutaneous syndrome", 0.0], ["P31749", "AKT1", "RAC-alpha serine/threonine-protein kinase", 1, 5, "Proteus syndrome", 0.0], ["P13010", "XRCC5", "DNA repair protein Ku80", 1, 1, "HIV infection", 0.0], ["P09601", "HMOX1", "Heme oxygenase 1", 1, 6, "heme oxygenase 1 deficiency", 0.0], ["Q9HD33", "MRPL47", "Large ribosomal subunit protein uL29m", 1, 5, "Delayed speech and language development", 0.0], ["P35221", "CTNNA1", "Catenin alpha-1", 1, 2, "Butterfly-shaped pigment dystrophy", 0.0], ["P13984", "GTF2F2", "General transcription factor IIF subunit 2", 1, 1, "HIV infection", 0.0], ["Q9NR28", "DIABLO", "Diablo IAP-binding mitochondrial protein", 1, 2, "autosomal dominant nonsyndromic hearing loss", 0.0], ["P49137", "MAPKAPK2", "MAP kinase-activated protein kinase 2", 1, 1, "neurodegenerative disease", 0.0], ["Q9Y399", "MRPS2", "Small ribosomal subunit protein uS2m", 1, 9, "combined oxidative phosphorylation deficiency 36", 0.0], ["P09874", "PARP1", "Poly [ADP-ribose] polymerase 1", 1, 9, "ovarian cancer", 0.0], ["P55072", "VCP", "Transitional endoplasmic reticulum ATPase", 1, 1, "inclusion body myopathy with Paget disease of bone and frontotemporal dementia type 1", 0.0], ["P45983", "MAPK8", "Mitogen-activated protein kinase 8", 1, 2, "cancer", 0.0], ["P53355", "DAPK1", "Death-associated protein kinase 1", 1, 1, "neurodegenerative disease", 0.0], ["Q9H2U1", "DHX36", "ATP-dependent DNA/RNA helicase DHX36", 1, 1, "Abnormality of the skeletal system", 0.0], ["Q9Y6K9", "IKBKG", "NF-kappa-B essential modulator", 1, 2, "incontinentia pigmenti", 0.0], ["Q14790", "CASP8", "Caspase-8", 1, 9, "Autoimmune lymphoproliferative syndrome with recurrent viral infections", 0.0], ["Q07960", "ARHGAP1", "Rho GTPase-activating protein 1", 1, 2, "heart disease", 0.0], ["P82933", "MRPS9", "Small ribosomal subunit protein uS9m", 1, 9, "neurodegenerative disease", 0.0], ["P29597", "TYK2", "Non-receptor tyrosine-protein kinase TYK2", 1, 1, "immunodeficiency 35", 0.0], ["Q8IXJ6", "SIRT2", "NAD-dependent protein deacetylase sirtuin-2", 1, 4, "neoplasm", 0.0], ["P61587", "RND3", "Rho-related GTP-binding protein RhoE", 1, 1, "azoospermia", 0.0], ["P45984", "MAPK9", "Mitogen-activated protein kinase 9", 1, 1, "cancer", 0.0], ["P55854", "SUMO3", "Small ubiquitin-related modifier 3", 1, 2, "fragile X-associated tremor/ataxia syndrome", 0.0], ["P28676", "GCA", "Grancalcin", 1, 7, "intelligence", 0.0], ["P06241", "FYN", "Tyrosine-protein kinase Fyn", 1, 5, "chronic myelogenous leukemia", 0.0], ["P41743", "PRKCI", "Protein kinase C iota type", 1, 2, "acute myeloid leukemia", 0.0], ["P55211", "CASP9", "Caspase-9", 1, 8, "neurodegenerative disease", 0.0], ["Q14653", "IRF3", "Interferon regulatory factor 3", 1, 5, "Herpetic encephalitis", 0.0], ["Q12769", "NUP160", "Nuclear pore complex protein Nup160", 1, 2, "nephrotic syndrome", 0.0], ["P11387", "TOP1", "DNA topoisomerase 1", 1, 4, "small cell lung carcinoma", 0.0], ["Q15691", "MAPRE1", "Microtubule-associated protein RP/EB family member 1", 1, 1, "neurodegenerative disease", 0.0], ["O94925", "GLS", "Glutaminase kidney isoform, mitochondrial", 1, 2, "global developmental delay, progressive ataxia, and elevated glutamine", 0.0], ["Q7RTN6", "STRADA", "STE20-related kinase adapter protein alpha", 1, 7, "polyhydramnios, megalencephaly, and symptomatic epilepsy", 0.0], ["Q13137", "CALCOCO2", "Calcium-binding and coiled-coil domain-containing protein 2", 1, 1, "Abnormality of the skeletal system", 0.0], ["Q9P289", "STK26", "Serine/threonine-protein kinase 26", 1, 3, "hepatocellular carcinoma", 0.0], ["P24864", "CCNE1", "G1/S-specific cyclin-E1", 1, 1, "Abnormality of the skeletal system", 0.0], ["Q9UBU9", "NXF1", "Nuclear RNA export factor 1", 1, 1, "chronic lymphocytic leukemia", 0.0], ["O75534", "CSDE1", "Cold shock domain-containing protein E1", 1, 1, "neurodegenerative disease", 0.0], ["P61011", "SRP54", "Signal recognition particle subunit SRP54", 1, 1, "neutropenia, severe congenital, 8, autosomal dominant", 0.0], ["P49257", "LMAN1", "Protein ERGIC-53", 1, 1, "factor V and factor VIII, combined deficiency of, type 1", 0.0], ["P53779", "MAPK10", "Mitogen-activated protein kinase 10", 1, 1, "gout", 0.0], ["Q8NE86", "MCU", "Calcium uniporter protein, mitochondrial", 1, 2, "neurodegenerative disease", 0.0], ["P15927", "RPA2", "Replication protein A 32 kDa subunit", 1, 1, "neurodegenerative disease", 0.0], ["Q13330", "MTA1", "Metastasis-associated protein MTA1", 1, 1, "neurodegenerative disease", 0.0], ["P29558", "RBMS1", "RNA-binding motif, single-stranded-interacting protein 1", 1, 1, "neurodegenerative disease", 0.0], ["P51532", "SMARCA4", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", 1, 1, "intellectual disability, autosomal dominant 16", 0.0], ["Q9NTZ6", "RBM12", "RNA-binding protein 12", 1, 174, "neurodegenerative disease", 0.0], ["Q86V81", "ALYREF", "THO complex subunit 4", 1, 1, null, 0.0], ["P00519", "ABL1", "Tyrosine-protein kinase ABL1", 1, 5, "chronic myelogenous leukemia", 0.0], ["Q9NY12", "GAR1", "H/ACA ribonucleoprotein complex subunit 1", 1, 1, "neurodegenerative disease", 0.0], ["P55957", "BID", "BH3-interacting domain death agonist", 1, 1, "neurodegenerative disease", 0.0], ["P22681", "CBL", "E3 ubiquitin-protein ligase CBL", 1, 4, "Noonan syndrome-like disorder with juvenile myelomonocytic leukemia", 0.0], ["Q14103", "HNRNPD", "Heterogeneous nuclear ribonucleoprotein D0", 1, 4, "dengue disease", 0.0], ["P29353", "SHC1", "SHC-transforming protein 1", 1, 2, "cancer", 0.0], ["P67809", "YBX1", "Y-box-binding protein 1", 1, 9, "dengue disease", 0.0], ["P19338", "NCL", "Nucleolin", 1, 541, "neurodegenerative disease", 0.0], ["Q14432", "PDE3A", "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A", 1, 1, "Brachydactyly - arterial hypertension", 0.0], ["P50402", "EMD", "Emerin", 1, 5, "X-linked Emery-Dreifuss muscular dystrophy", 0.0], ["Q7Z4V5", "HDGFL2", "Hepatoma-derived growth factor-related protein 2", 1, 1, "Miyoshi myopathy", 0.0], ["P04150", "NR3C1", "Glucocorticoid receptor", 1, 5, "glucocorticoid resistance", 0.0], ["Q9Y5A9", "YTHDF2", "YTH domain-containing family protein 2", 1, 1, "neurodegenerative disease", 0.0], ["P46937", "YAP1", "Transcriptional coactivator YAP1", 1, 4, "uveal coloboma-cleft lip and palate-intellectual disability", 0.0], ["Q14444", "CAPRIN1", "Caprin-1", 1, 1, "neurodegeneration, childhood-onset, with cerebellar ataxia and cognitive decline", 0.0], ["P43694", "GATA4", "Transcription factor GATA-4", 1, 1, "atrial septal defect 2", 0.0], ["Q13469", "NFATC2", "Nuclear factor of activated T-cells, cytoplasmic 2", 1, 1, "hypertension", 0.0], ["P51608", "MECP2", "Methyl-CpG-binding protein 2", 1, 4, "Rett syndrome", 0.0], ["Q9HC77", "CPAP", "Centrosomal P4.1-associated protein", 1, 1, "autosomal recessive primary microcephaly", 0.0], ["Q7Z3T8", "ZFYVE16", "Zinc finger FYVE domain-containing protein 16", 1, 2, "liver disease", 0.0], ["P35637", "FUS", "RNA-binding protein FUS", 1, 8, "sporadic amyotrophic lateral sclerosis", 0.0], ["Q8WZ42", "TTN", "Titin", 1, 1, "dilated cardiomyopathy", 0.0], ["P78527", "PRKDC", "DNA-dependent protein kinase catalytic subunit", 1, 3, "severe combined immunodeficiency due to DNA-PKcs deficiency", 0.0], ["P36969", "GPX4", "Phospholipid hydroperoxide glutathione peroxidase GPX4", 1, 5, "spondylometaphyseal dysplasia, Sedaghatian type", 0.0], ["O60315", "ZEB2", "Zinc finger E-box-binding homeobox 2", 1, 3, "Mowat-Wilson syndrome", 0.0], ["O75390", "CS", "Citrate synthase, mitochondrial", 1, 1467, "neurodegenerative disease", 0.0], ["O75674", "TOM1L1", "TOM1-like protein 1", 1, 1, "mitochondrial complex IV deficiency, nuclear type 23", 0.0], ["O75821", "EIF3G", "Eukaryotic translation initiation factor 3 subunit G", 1, 1, "narcolepsy-cataplexy syndrome", 0.0], ["O75828", "CBR3", "Carbonyl reductase [NADPH] 3", 1, 38, "prostate carcinoma", 0.0], ["O94923", "GLCE", "D-glucuronyl C5-epimerase", 1, 1, "Abnormality of the skeletal system", 0.0], ["P09668", "CTSH", "Pro-cathepsin H", 1, 1, "type 1 diabetes mellitus", 0.0], ["P09936", "UCHL1", "Ubiquitin carboxyl-terminal hydrolase isozyme L1", 1, 2, "early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome", 0.0], ["P17096", "HMGA1", "High mobility group protein HMG-I/HMG-Y", 1, 4, "HIV infection", 0.0], ["P17252", "PRKCA", "Protein kinase C alpha type", 1, 1, "acute myeloid leukemia", 0.0], ["P36959", "GMPR", "GMP reductase 1", 1, 1, "hypertrophic cardiomyopathy", 0.0], ["P42680", "TEC", "Tyrosine-protein kinase Tec", 1, 13, "alopecia areata", 0.0], ["P45973", "CBX5", "Chromobox protein homolog 5", 1, 2, "Abnormality of the skeletal system", 0.0], ["P48728", "AMT", "Aminomethyltransferase, mitochondrial", 1, 6, "glycine encephalopathy", 0.0], ["P50897", "PPT1", "Palmitoyl-protein thioesterase 1", 1, 2, "neuronal ceroid lipofuscinosis 1", 0.0], ["P53701", "HCCS", "Holocytochrome c-type synthase", 1, 3, "Microphthalmia with linear skin defects syndrome", 0.0], ["P55263", "ADK", "Adenosine kinase", 1, 2, "adenosine kinase deficiency", 0.0], ["P57075", "UBASH3A", "Ubiquitin-associated and SH3 domain-containing protein A", 1, 1, "rheumatoid arthritis", 0.0], ["P63172", "DYNLT1", "Dynein light chain Tctex-type 1", 1, 1, "dengue disease", 0.0], ["P83916", "CBX1", "Chromobox protein homolog 1", 1, 2, "viral disease", 0.0], ["P84103", "SRSF3", "Serine/arginine-rich splicing factor 3", 1, 2, "open-angle glaucoma", 0.0], ["Q00341", "HDLBP", "Vigilin", 1, 2, "dengue disease", 0.0], ["Q06203", "PPAT", "Amidophosphoribosyltransferase", 1, 1, "rheumatoid arthritis", 0.0], ["Q13043", "STK4", "Serine/threonine-protein kinase 4", 1, 1, "combined immunodeficiency due to STK4 deficiency", 0.0], ["Q13158", "FADD", "FAS-associated death domain protein", 1, 3, "FADD-related immunodeficiency", 0.0], ["Q15366", "PCBP2", "Poly(rC)-binding protein 2", 1, 2, "severe acute respiratory syndrome", 0.0], ["Q5JSP0", "FGD3", "FYVE, RhoGEF and PH domain-containing protein 3", 1, 1, "anaphylaxis", 0.0], ["Q7L7L0", "H2AC25", "Histone H2A type 3", 1, 2, "infectious disease", 0.0], ["Q8WW12", "PCNP", "PEST proteolytic signal-containing nuclear protein", 1, 1, "asthma", 0.0], ["Q96I24", "FUBP3", "Far upstream element-binding protein 3", 1, 1, "ulna fracture", 0.0], ["Q96PY5", "FMNL2", "Formin-like protein 2", 1, 1, "open-angle glaucoma", 0.0], ["Q9BUB7", "TMEM70", "Transmembrane protein 70, mitochondrial", 1, 2, "mitochondrial complex V (ATP synthase) deficiency, nuclear type 2", 0.0], ["Q9H8M7", "MINDY3", "Ubiquitin carboxyl-terminal hydrolase MINDY-3", 1, 5, "neuroendocrine neoplasm", 0.0], ["Q9H8W4", "PLEKHF2", "Pleckstrin homology domain-containing family F member 2", 1, 1, "Abnormality of the skeletal system", 0.0], ["Q9UJY5", "GGA1", "ADP-ribosylation factor-binding protein GGA1", 1, 2, "azoospermia", 0.0], ["Q9ULQ1", "TPCN1", "Two pore channel protein 1", 1, 1, "placental retention", 0.0], ["Q9UPU5", "USP24", "Ubiquitin carboxyl-terminal hydrolase 24", 1, 1, "metabolic disease", 0.0], ["Q9Y646", "CPQ", "Carboxypeptidase Q", 1, 1, "risk-taking behaviour", 0.0], ["A6NDG6", "PGP", "Glycerol-3-phosphate phosphatase", 1, 18, "neurodegenerative disease", 0.0], ["O14578", "CIT", "Citron Rho-interacting kinase", 1, 11, "autosomal recessive primary microcephaly", 0.0], ["O15021", "MAST4", "Microtubule-associated serine/threonine-protein kinase 4", 1, 1, "Neurodevelopmental disorder", 0.0], ["O60507", "TPST1", "Protein-tyrosine sulfotransferase 1", 1, 1, "smoking initiation", 0.0], ["O94900", "TOX", "Thymocyte selection-associated high mobility group box protein TOX", 1, 2, "neurodegenerative disease", 0.0], ["P05165", "PCCA", "Propionyl-CoA carboxylase alpha chain, mitochondrial", 1, 1, "propionic acidemia", 0.0], ["P12270", "TPR", "Nucleoprotein TPR", 1, 1, "HIV infection", 0.0], ["P21397", "MAOA", "Amine oxidase [flavin-containing] A", 1, 2, "Brunner syndrome", 0.0], ["P35475", "IDUA", "Alpha-L-iduronidase", 1, 1, "Scheie syndrome", 0.0], ["P39880", "CUX1", "Homeobox protein cut-like 1", 1, 1, "global developmental delay with or without impaired intellectual development", 0.0], ["P48637", "GSS", "Glutathione synthetase", 1, 1, "Glutathione synthetase deficiency", 0.0], ["P49915", "GMPS", "GMP synthase [glutamine-hydrolyzing]", 1, 2, "lupus nephritis", 0.0], ["P50502", "ST13", "Hsc70-interacting protein", 1, 2, "neurodegenerative disease", 0.0], ["P84090", "ERH", "Enhancer of rudimentary homolog", 1, 1, "neurodegenerative disease", 0.0], ["Q08J23", "NSUN2", "RNA cytosine C(5)-methyltransferase NSUN2", 1, 1, "autosomal recessive non-syndromic intellectual disability", 0.0], ["Q13247", "SRSF6", "Serine/arginine-rich splicing factor 6", 1, 1, "dengue disease", 0.0], ["Q53H12", "AGK", "Acylglycerol kinase, mitochondrial", 1, 1, "Sengers syndrome", 0.0], ["Q5VT25", "CDC42BPA", "Serine/threonine-protein kinase MRCK alpha", 1, 2, "neurodegenerative disease", 0.0], ["Q6NUK1", "SLC25A24", "Mitochondrial adenyl nucleotide antiporter SLC25A24", 1, 1, "Fontaine progeroid syndrome", 0.0], ["P06276", "BCHE", "Cholinesterase", 1, 13, "butyrylcholinesterase deficiency", null], ["Q13822", "ENPP2", "Autotaxin", 1, 2, "Abnormality of the skeletal system", null], ["P00751", "CFB", "Complement factor B", 1, 3, null, null], ["P02679", "FGG", "Fibrinogen gamma chain", 1, 8, "familial dysfibrinogenemia", null], ["Q96QC4", "MICA", null, 1, 7, null, null], ["P07204", "THBD", "Thrombomodulin", 1, 5, "thrombomodulin-related bleeding disorder", null], ["P19429", "TNNI3", "Troponin I, cardiac muscle", 1, 1, "hypertrophic cardiomyopathy", null], ["P82664", "MRPS10", "Small ribosomal subunit protein uS10m", 1, 9, "neurodegenerative disease", null], ["O60462", "NRP2", "Neuropilin-2", 1, 2, "esophageal disease", null], ["P45379", "TNNT2", "Troponin T, cardiac muscle", 1, 4, "hypertrophic cardiomyopathy", null], ["P82914", "MRPS15", "Small ribosomal subunit protein uS15m", 1, 9, "neurodegenerative disease", null], ["P08603", "CFH", "Complement factor H", 1, 4, "complement factor H deficiency", null], ["Q15465", "SHH", "Sonic hedgehog protein", 1, 4, "holoprosencephaly 3", null], ["P08174", "CD55", "Complement decay-accelerating factor", 1, 3, "Protein-losing enteropathy", null], ["P42345", "MTOR", "Serine/threonine-protein kinase mTOR", 1, 27, "Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome", null], ["P17181", "IFNAR1", "Interferon alpha/beta receptor 1", 1, 1, "immunodeficiency 106, susceptibility to viral infections", null], ["P26358", "DNMT1", "DNA (cytosine-5)-methyltransferase 1", 1, 12, "autosomal dominant cerebellar ataxia, deafness and narcolepsy", null], ["P08069", "IGF1R", "Insulin-like growth factor 1 receptor", 1, 10, "growth delay due to insulin-like growth factor I resistance", null], ["P78324", "SIRPA", "Tyrosine-protein phosphatase non-receptor type substrate 1", 1, 1, "type 2 diabetes mellitus", null], ["P57764", "GSDMD", "Gasdermin-D", 1, 6, "Oral ulcer", null], ["P06729", "CD2", "T-cell surface antigen CD2", 1, 86, "rheumatoid arthritis", null], ["P06213", "INSR", "Insulin receptor", 1, 14, "Leprechaunism", null], ["P02775", "PPBP", "Platelet basic protein", 1, 3, "neoplasm", null], ["O00425", "IGF2BP3", "Insulin-like growth factor 2 mRNA-binding protein 3", 1, 1, "neurodegenerative disease", null], ["Q9HAU5", "UPF2", "Regulator of nonsense transcripts 2", 1, 2, "autism spectrum disorder", null], ["P01833", "PIGR", "Polymeric immunoglobulin receptor", 1, 2, "clear cell renal carcinoma", null], ["P22087", "FBL", "rRNA 2'-O-methyltransferase fibrillarin", 1, 6, "neurodegenerative disease", null], ["Q8N884", "CGAS", "Cyclic GMP-AMP synthase", 1, 23, "dengue disease", null], ["Q13490", "BIRC2", "Baculoviral IAP repeat-containing protein 2", 1, 1, "neurodegenerative disease", null], ["P02545", "LMNA", "Prelamin-A/C", 1, 1, "dilated cardiomyopathy", null], ["Q14457", "BECN1", "Beclin-1", 1, 1, "neurodegenerative disease", null], ["P50914", "RPL14", "Large ribosomal subunit protein eL14", 1, 1, "influenza", null], ["P14635", "CCNB1", "G2/mitotic-specific cyclin-B1", 1, 1, "neurodegenerative disease", null], ["Q16790", "CA9", "Carbonic anhydrase 9", 1, 1, "epilepsy", null], ["P01584", "IL1B", "Interleukin-1 beta", 1, 8, "cryopyrin-associated periodic syndrome", null], ["Q08345", "DDR1", "Epithelial discoidin domain-containing receptor 1", 1, 1, null, null], ["P53999", "SUB1", "Activated RNA polymerase II transcriptional coactivator p15", 1, 1, "breast carcinoma", null], ["Q9NQX4", "MYO5C", "Unconventional myosin-Vc", 1, 1, "type 2 diabetes mellitus", null], ["P08575", "PTPRC", "Receptor-type tyrosine-protein phosphatase C", 1, 1, "immunodeficiency 104", null], ["P24928", "POLR2A", "DNA-directed RNA polymerase II subunit RPB1", 1, 1, null, null], ["Q16832", "DDR2", "Discoidin domain-containing receptor 2", 1, 1, "spondyloepimetaphyseal dysplasia-short limb-abnormal calcification syndrome", null], ["P02649", "APOE", "Apolipoprotein E", 1, 41, "coronary artery disease", null], ["Q9H0M0", "WWP1", "NEDD4-like E3 ubiquitin-protein ligase WWP1", 1, 1, "gout", null], ["P02511", "CRYAB", "Alpha-crystallin B chain", 1, 2, "myofibrillar myopathy 2", null], ["P20936", "RASA1", "Ras GTPase-activating protein 1", 1, 1, "capillary malformation-arteriovenous malformation 1", null], ["P01130", "LDLR", "Low-density lipoprotein receptor", 1, 18, "hypercholesterolemia, familial, 1", null], ["P04637", "TP53", "Cellular tumor antigen p53", 1, 13, "Li-Fraumeni syndrome", null], ["P30530", "AXL", "Tyrosine-protein kinase receptor UFO", 1, 22, "acute myeloid leukemia", null], ["P37840", "SNCA", "Alpha-synuclein", 1, 62, "Hereditary late-onset Parkinson disease", null], ["Q9BVP2", "GNL3", "Guanine nucleotide-binding protein-like 3", 1, 1, "neurodegenerative disease", null], ["O14965", "AURKA", "Aurora kinase A", 1, 2, "neurodegenerative disease", null], ["Q9NTG7", "SIRT3", "NAD-dependent protein deacetylase sirtuin-3, mitochondrial", 1, 1, "uterine fibroid", null], ["O60502", "OGA", "Protein O-GlcNAcase", 1, 1, "atrial fibrillation", null], ["O75533", "SF3B1", "Splicing factor 3B subunit 1", 1, 1, "chronic lymphocytic leukemia", null], ["Q8WTT2", "NOC3L", "Nucleolar complex protein 3 homolog", 1, 1, "hypertension", null], ["P11388", "TOP2A", "DNA topoisomerase 2-alpha", 1, 1, "neoplasm", null], ["P40189", "IL6ST", "Interleukin-6 receptor subunit beta", 1, 2, "Autosomal recessive hyper-IgE syndrome", null], ["P24821", "TNC", "Tenascin", 1, 49, "autosomal dominant nonsyndromic hearing loss", null], ["P33316", "DUT", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", 1, 1, "bone marrow failure and diabetes mellitus syndrome", null], ["Q05397", "PTK2", "Focal adhesion kinase 1", 1, 3, "neurodegenerative disease", null], ["P05455", "SSB", "Lupus La protein", 1, 17, "neurodegenerative disease", null], ["P98170", "XIAP", "E3 ubiquitin-protein ligase XIAP", 1, 4, "X-linked lymphoproliferative disease", null], ["P22607", "FGFR3", "Fibroblast growth factor receptor 3", 1, 6, "achondroplasia", null], ["P11362", "FGFR1", "Fibroblast growth factor receptor 1", 1, 13, "hypogonadotropic hypogonadism 2 with or without anosmia", null], ["Q9Y3A5", "SBDS", "Ribosome maturation protein SBDS", 1, 1, "Shwachman-Diamond syndrome", null], ["Q08945", "SSRP1", "FACT complex subunit SSRP1", 1, 1, "HIV infection", null], ["P17931", "LGALS3", "Galectin-3", 1, 4, "Arthropathy", null], ["P21802", "FGFR2", "Fibroblast growth factor receptor 2", 1, 5, "Crouzon syndrome", null], ["P26045", "PTPN3", "Tyrosine-protein phosphatase non-receptor type 3", 1, 2, "stomach disease", null], ["Q13153", "PAK1", "Serine/threonine-protein kinase PAK 1", 1, 2, "intellectual developmental disorder with macrocephaly, seizures, and speech delay", null], ["P07602", "PSAP", "Prosaposin", 1, 1, "Gaucher disease due to saposin C deficiency", null], ["P22455", "FGFR4", "Fibroblast growth factor receptor 4", 1, 2, "cancer", null], ["P21580", "TNFAIP3", "Tumor necrosis factor alpha-induced protein 3", 1, 2, "autoinflammatory syndrome, familial, Behcet-like 1", null], ["P59665", "DEFA1", "Neutrophil defensin 1", 1, 2, "IGA glomerulonephritis", null], ["Q15075", "EEA1", "Early endosome antigen 1", 1, 1, "neuroinflammatory disorder", null], ["Q15303", "ERBB4", "Receptor tyrosine-protein kinase erbB-4", 1, 3, "non-small cell lung carcinoma", null], ["P26368", "U2AF2", "Splicing factor U2AF 65 kDa subunit", 1, 2, "developmental delay, dysmorphic facies, and brain anomalies", null], ["P78504", "JAG1", "Protein jagged-1", 1, 4, "Alagille syndrome due to a JAG1 point mutation", null], ["Q92888", "ARHGEF1", "Rho guanine nucleotide exchange factor 1", 1, 6, "immunodeficiency 62", null], ["P07988", "SFTPB", "Pulmonary surfactant-associated protein B", 1, 1, "Neonatal acute respiratory distress with surfactant metabolism deficiency", null], ["P11717", "IGF2R", "Cation-independent mannose-6-phosphate receptor", 1, 5, "coronary artery disease", null], ["P19838", "NFKB1", "Nuclear factor NF-kappa-B p105 subunit", 1, 2, "common variable immunodeficiency", null], ["P55884", "EIF3B", "Eukaryotic translation initiation factor 3 subunit B", 1, 2, "injury", null], ["Q92900", "UPF1", "Regulator of nonsense transcripts 1", 1, 1, "Global developmental delay", null], ["Q9H6X2", "ANTXR1", "Anthrax toxin receptor 1", 1, 2, "GAPO syndrome", null], ["Q07817", "BCL2L1", "Bcl-2-like protein 1", 1, 6, "neurodegenerative disease", null], ["P10515", "DLAT", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial", 1, 1, "pyruvate dehydrogenase E2 deficiency", null], ["Q04206", "RELA", "Transcription factor p65", 1, 14, "mucocutaneous ulceration, chronic", null], ["O00443", "PIK3C2A", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", 1, 1, "oculocerebrodental syndrome", null], ["P58335", "ANTXR2", "Anthrax toxin receptor 2", 1, 4, "hyaline fibromatosis syndrome", null], ["Q86UW9", "DTX2", "Probable E3 ubiquitin-protein ligase DTX2", 1, 3, "neurodegenerative disease", null], ["Q12797", "ASPH", "Aspartyl/asparaginyl beta-hydroxylase", 1, 2, "facial dysmorphism-lens dislocation-anterior segment abnormalities-spontaneous filtering blebs syndrome", null], ["Q9NNX6", "CD209", "CD209 antigen", 1, 1, "dengue disease", null], ["P35968", "KDR", "Vascular endothelial growth factor receptor 2", 1, 22, "neoplasm", null], ["P19438", "TNFRSF1A", "Tumor necrosis factor receptor superfamily member 1A", 1, 1, "TNF receptor 1-associated periodic fever syndrome", null], ["Q07955", "SRSF1", "Serine/arginine-rich splicing factor 1", 1, 1, "neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities", null], ["P30050", "RPL12", "Large ribosomal subunit protein uL11", 1, 1, "influenza", null], ["P24592", "IGFBP6", "Insulin-like growth factor-binding protein 6", 1, 2, "hypertension", null], ["Q13554", "CAMK2B", "Calcium/calmodulin-dependent protein kinase type II subunit beta", 1, 2, "intellectual disability, autosomal dominant 54", null], ["P01133", "EGF", "Pro-epidermal growth factor", 1, 34, "cancer", null], ["P09038", "FGF2", "Fibroblast growth factor 2", 1, 53, "cancer", null], ["P11836", "MS4A1", "B-lymphocyte antigen CD20", 1, 2, "chronic lymphocytic leukemia", null], ["Q9Y3T9", "NOC2L", "Nucleolar complex protein 2 homolog", 1, 1, "neurodegenerative disease", null], ["P29590", "PML", "Protein PML", 1, 5, "uterine fibroid", null], ["Q13563", "PKD2", "Polycystin-2", 1, 3, "polycystic kidney disease 2", null], ["Q13546", "RIPK1", "Receptor-interacting serine/threonine-protein kinase 1", 1, 2, "immunodeficiency 57", null], ["Q06787", "FMR1", "Fragile X messenger ribonucleoprotein 1", 1, 9, "fragile X syndrome", null], ["Q8N163", "CCAR2", "Cell cycle and apoptosis regulator protein 2", 1, 5, "Abnormality of refraction", null], ["P22004", "BMP6", "Bone morphogenetic protein 6", 1, 1, "Tangier disease", null], ["P55265", "ADAR", "Double-stranded RNA-specific adenosine deaminase", 1, 8, "Aicardi-Goutieres syndrome 6", null], ["P27448", "MARK3", "MAP/microtubule affinity-regulating kinase 3", 1, 2, "cancer", null], ["B7Z5N5", "SMAD2", "Mothers against decapentaplegic homolog", 1, 7, "Loeys-Dietz syndrome 6", null], ["Q13123", "IK", "Protein Red", 1, 4, "mitochondrial complex I deficiency, nuclear type 13", null], ["O75381", "PEX14", "Peroxisomal membrane protein PEX14", 1, 1, "Zellweger syndrome", null], ["P09651", "HNRNPA1", "Heterogeneous nuclear ribonucleoprotein A1", 1, 9, "amyotrophic lateral sclerosis", null], ["P04049", "RAF1", "RAF proto-oncogene serine/threonine-protein kinase", 1, 4, "Noonan syndrome", null], ["P23246", "SFPQ", "Splicing factor, proline- and glutamine-rich", 1, 4, "tuberculosis", null], ["P05067", "APP", "Amyloid-beta precursor protein", 1, 63, "Alzheimer disease", null], ["P04004", "VTN", "Vitronectin", 1, 10, "hypertension", null], ["Q13501", "SQSTM1", "Sequestosome-1", 1, 4, "amyotrophic lateral sclerosis", null], ["Q13283", "G3BP1", "Ras GTPase-activating protein-binding protein 1", 1, 2, "neurodegenerative disease", null], ["Q16637", "SMN1", "Survival motor neuron protein", 1, 1, "Proximal spinal muscular atrophy type 3", null], ["Q14498", "RBM39", "RNA-binding protein 39", 1, 1, "neurodegenerative disease", null], ["Q9UHD8", "SEPTIN9", "Septin-9", 1, 1, "neuralgic amyotrophy", null], ["Q9NR56", "MBNL1", "Muscleblind-like protein 1", 1, 3, "type 2 diabetes mellitus", null], ["P15056", "BRAF", "Serine/threonine-protein kinase B-raf", 1, 6, "cardiofaciocutaneous syndrome", null], ["Q92879", "CELF1", "CUGBP Elav-like family member 1", 1, 3, "Abnormality of the skeletal system", null], ["P01042", "KNG1", "Kininogen-1", 1, 3, "congenital high-molecular-weight kininogen deficiency", null], ["O14976", "GAK", "Cyclin-G-associated kinase", 1, 1, "Parkinson disease", null], ["O95819", "MAP4K4", "Mitogen-activated protein kinase kinase kinase kinase 4", 1, 1, "neurodegenerative disease", null], ["Q13263", "TRIM28", "Transcription intermediary factor 1-beta", 1, 1, "Wilms tumor", null], ["Q13148", "TARDBP", "TAR DNA-binding protein 43", 1, 7, "amyotrophic lateral sclerosis", null], ["Q13164", "MAPK7", "Mitogen-activated protein kinase 7", 1, 2, "self-injurious ideation", null], ["P49023", "PXN", "Paxillin", 1, 1, "atrial fibrillation", null], ["P61978", "HNRNPK", "Heterogeneous nuclear ribonucleoprotein K", 1, 3, "Au-Kline syndrome", null], ["P42224", "STAT1", "Signal transducer and activator of transcription 1-alpha/beta", 1, 5, "Chronic mucocutaneous candidosis", null], ["Q9NQX5", "NPDC1", "Neural proliferation differentiation and control protein 1", 1, 2, "neurodegenerative disease", null], ["O00187", "MASP2", "Mannan-binding lectin serine protease 2", 1, 1, "immunodeficiency due to MASP-2 deficiency", null]], "truncated": false, "columns": ["id", "gene_symbol", "protein_name", "in_cev_map", "aptamer_count_pubmed", "opentargets_top_disease_name", "priority_score"], "query": {"sql": "SELECT id, gene_symbol, protein_name, in_cev_map, aptamer_count_pubmed, opentargets_top_disease_name, priority_score FROM v_targets WHERE has_known_aptamer=1 AND in_cev_map=1 ORDER BY priority_score DESC", "params": {}}, "error": null, "private": false, "allow_execute_sql": true, "query_ms": 10.14463300089119, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}