id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
63,CD8a,protein,P01732,A8,,5.59 nM,-8.253,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,binding buffer with 0.01% Tween 20,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 ± 0.2,  14.7 ± 0.1  and  5.59 ± 0.11  nM, respectively",step2c_literal_v3
87,transferrin receptor 1,protein,P02786,JBA8.26,,6.87 nM,-8.163,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,,,,,DNA,,35875870,10.1021/jacs.2c05349,"Using BLI, JBA8.26 was found to bind immobilized TfR1 with a K D of 6.87 ± 0.04 nM",step2c_literal_v3
62,CD8a,protein,P01732,A3,,14.7 nM,-7.833,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,binding buffer with 0.01% Tween 20,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 ± 0.2,  14.7 ± 0.1  and  5.59 ± 0.11  nM, respectively",step2c_literal_v3
61,CD8a,protein,P01732,A1,,20.1 nM,-7.697,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,binding buffer with 0.01% Tween 20,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 ± 0.2,  14.7 ± 0.1  and  5.59 ± 0.11  nM, respectively",step2c_literal_v3
128,CD117,protein,P10721,Apta02,,21.8 nM,-7.662,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,,,DNA,,40487293,10.1002/adfm.202425394,"Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 µ m, respectively ( Figure 2 a,b).",step2c_literal_v3
86,transferrin receptor 1,protein,P02786,tJBA8.1,,25.11 nM,-7.6,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,,,,,DNA,biotinylated,35875870,10.1021/jacs.2c05349,tJBA8.1 bound the TfR1 protein with a K D value of 25.11 ± 0.19 nM,step2c_literal_v3
129,CD117,protein,P10721,Apta04,,1100.0 nM,-5.959,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,,,DNA,,40487293,10.1002/adfm.202425394,"Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 µ m, respectively ( Figure 2 a,b).",step2c_literal_v3
131,CD123,protein,O75794,Apta25,,1.16 µM,-5.936,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,,,DNA,,40487293,10.1002/adfm.202425394,"BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 µ m for ZW25 and 15.6 µ m for CY30 (Figure S2, Supporting Information).",step2c_literal_v3
130,CD123,protein,O75794,Apta30,,15.6 µM,-4.807,intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,BLI,298.15,,,,DNA,,40487293,10.1002/adfm.202425394,"BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 µ m for ZW25 and 15.6 µ m for CY30 (Figure S2, Supporting Information).",step2c_literal_v3