id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
117,CD20,protein,P11836,Aptamer 2,,1.2 μM,-5.921,intrinsic,Kd,Gold,v4,extraction_verified,pending_manual_supp,,,ITC,298.15,7.4,TGK Buffer,,DNA,,39004051,10.1016/j.bmc.2024.117831,| 2 | 1.2 ± 0.2 | 1.49 ± 0.01 | > mM | N/D |,step2c_literal_v3
120,CD20,protein,P11836,Aptamer 2-f1,,5.5 μM,-5.26,intrinsic,Kd,Gold,v4,extraction_verified,pending_manual_supp,,,ITC,298.15,7.4,TGK Buffer,,DNA,,39004051,10.1016/j.bmc.2024.117831,| 2-f1 | 5.5 ± 1.3 | 1.46 ± 0.03 | > mM | N/D |,step2c_literal_v3
116,CD20,protein,P11836,Aptamer 1,,6.4 μM,-5.194,intrinsic,Kd,Gold,v4,extraction_verified,pending_manual_supp,,,ITC,298.15,7.4,TGK Buffer,,DNA,,39004051,10.1016/j.bmc.2024.117831,| 1 | 6.4 ± 1.0 | 0.86 ± 0.01 | N/D | N/D |,step2c_literal_v3
118,CD20,protein,P11836,Aptamer 1-f1,,9.0 μM,-5.046,intrinsic,Kd,Gold,v4,extraction_verified,pending_manual_supp,,,ITC,298.15,7.4,TGK Buffer,,DNA,,39004051,10.1016/j.bmc.2024.117831,| 1-f1 | 9.0 ± 2.4 | 0.98 ± 0.02 | > mM | N/D |,step2c_literal_v3
462,Patulin,protein,,PTL-1,,1.2499999999999999e-05 M,-4.903,intrinsic,Kd,Gold,v4,multi_agent_verified,pending_manual_supp,,,ITC,298.15,6.0,"selection buffer (10 mM MES, pH 6.0, 150 mM NaCl, 5 mM MgCl2)",,DNA,,41473783,10.1186/s44280-025-00101-2,The measured K d from ITC value was 12.5 μM,step2c_acs_v1
119,CD20,protein,P11836,Aptamer 1-f2,,18.9 μM,-4.724,intrinsic,Kd,Gold,v4,extraction_verified,pending_manual_supp,,,ITC,298.15,7.4,TGK Buffer,,DNA,,39004051,10.1016/j.bmc.2024.117831,| 1-f2 | 18.9 ± 3.3 | 1.07 ± 0.03 | > mM | N/D |,step2c_literal_v3
470,L-lactate,protein,Q9BYZ2,Lac2059,,0.00011 M,-3.959,intrinsic,Kd,Gold,v4,multi_agent_verified,pending_manual_supp,,,ITC,298.15,,SELEX buffer,,DNA,,41779931,10.1021/acs.analchem.5c07149,The K d from ITC was determined to be 0.11 mM,step2c_acs_v1