id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
154,thrombin,protein,P00734,HD1-22,GGTTGGTGTGGTTGGAAAAAAAAAAAAGTCCGTGGTAGGGCAGGTTGGGGTGACT,6.5e-10 M,-9.187,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,bivalent fusion; poly-dA linker,18826387,10.1111/j.1538-7836.2008.03162.x,HD1-22 | Thrombin | K D ( M) | 6.5 · 10 ) 10,step2c_literal_v3
251,Human thrombin,protein,P00734,Pse08-29,TGACCTCTAGTGACTGATTTACGAGTC,2.6 nM,-8.585,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,Pse(08 - 29) | 1.33 10^6 | 3.47 10^-3 | 2.6,step2c_literal_v3
156,prothrombin,protein,P00734,HD1,GGTTGGTGTGGTTGG,3.5e-09 M,-8.456,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,,18826387,10.1111/j.1538-7836.2008.03162.x,HD1 | Prothrombin+ phospholipids | K D ( M) | 3.5 · 10 ) 9,step2c_literal_v3
252,Mouse thrombin,protein,,Pse08-29,TGACCTCTAGTGACTGATTTACGAGTC,6.3 nM,-8.201,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,Pse(08 - 29) | 6.72 10^5 | 4.26 10^-3 | 6.3,step2c_literal_v3
194,α-thrombin,protein,P00734,TBA-iT7,GGTTGGTGTGGTTGG,9.9 nM,-8.004,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 7,30735210,10.1039/c9ob00053d,TBA-iT7 | 9.9,step2c_literal_v3
198,α-thrombin,protein,P00734,TBA-iT9,GGTTGGTGTGGTTGG,11.5 nM,-7.939,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 9,30735210,10.1039/c9ob00053d,TBA-iT9 | 11.5,step2c_literal_v3
196,α-thrombin,protein,P00734,TBA-G8-iT8,GGTTGGTTTGGTTGG,12.4 nM,-7.907,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 8,30735210,10.1039/c9ob00053d,TBA-G8-iT8 | 12.4,step2c_literal_v3
193,α-thrombin,protein,P00734,TBA-iT7,GGTTGGTGTGGTTGG,15.9 nM,-7.799,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 7,30735210,10.1039/c9ob00053d,TBA-iT7 | 15.9,step2c_literal_v3
189,α-thrombin,protein,P00734,TBA,GGTTGGTGTGGTTGG,27.2 nM,-7.565,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,,30735210,10.1039/c9ob00053d,TBA | 27.2,step2c_literal_v3
192,α-thrombin,protein,P00734,TBA-iT3,GGTTGGTGTGGTTGG,33.9 nM,-7.47,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 3,30735210,10.1039/c9ob00053d,TBA-iT3 | 33.9,step2c_literal_v3
200,α-thrombin,protein,P00734,TBA-iT12,GGTTGGTGTGGTTGG,37.0 nM,-7.432,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 12,30735210,10.1039/c9ob00053d,TBA-iT12 | 37.0,step2c_literal_v3
195,α-thrombin,protein,P00734,TBA-G8-iT8,GGTTGGTTTGGTTGG,37.1 nM,-7.431,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 8,30735210,10.1039/c9ob00053d,TBA-G8-iT8 | 37.1,step2c_literal_v3
197,α-thrombin,protein,P00734,TBA-iT9,GGTTGGTGTGGTTGG,41.0 nM,-7.387,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 9,30735210,10.1039/c9ob00053d,TBA-iT9 | 41.0,step2c_literal_v3
190,α-thrombin,protein,P00734,TBA,GGTTGGTGTGGTTGG,42.7 nM,-7.37,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,,30735210,10.1039/c9ob00053d,TBA | 42.7,step2c_literal_v3
199,α-thrombin,protein,P00734,TBA-iT12,GGTTGGTGTGGTTGG,46.8 nM,-7.33,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 12,30735210,10.1039/c9ob00053d,TBA-iT12 | 46.8,step2c_literal_v3
191,α-thrombin,protein,P00734,TBA-iT3,GGTTGGTGTGGTTGG,57.3 nM,-7.242,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 3,30735210,10.1039/c9ob00053d,TBA-iT3 | 57.3,step2c_literal_v3
155,prothrombin,protein,P00734,HD1-22,GGTTGGTGTGGTTGGAAAAAAAAAAAAGTCCGTGGTAGGGCAGGTTGGGGTGACT,6.7e-08 M,-7.174,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,bivalent fusion; poly-dA linker,18826387,10.1111/j.1538-7836.2008.03162.x,HD1-22 | Prothrombin+ phospholipids | K D ( M) | 6.7 · 10 ) 8,step2c_literal_v3