id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
44,IL-8,protein,P10145,8A-35,GGGGGCUUAUCAUUCCAUUUAGUGUUAUGAUAACC,1.72e-12 M,-11.764,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.0,7.4,"HBST running buffer (10 mM HEPES, pH 7.4, 150 mM NaCl, and 0.005% Tween 20)",,2'F-RNA,2'-fluoro-pyrimidine modified,24129312,10.1016/j.biomaterials.2013.09.107,| 8A-35       | 5.78 x 10 4 | 9.95 x 10 -8 | 1.72 x 10 -12 | 2.80         | 3.11 x 10 1  |,step2c_literal_v3
140,PDGF-C,protein,P01127,α-PC,CTACTGTGTGATGTCTGAGAGCAGCGTCTAAACGAACAAGCGAACCTATGCACAGAGGACAGTACATCAGACAC,20.0 pM,-10.699,intrinsic,KD,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,7.4,"HBS-EP + (10-mM HEPES, 150-mM NaCl, 3-mM EDTA, and 0.05% Tween 20, pH 7.4)",,DNA,PEG,42138517,10.1167/iovs.67.5.36,SPR analysis demonstrated that the α -PC aptamer bound tightly to PDGF-C with a dissociation constant ( KD ) of 20 pM,step2c_literal_v3
9,sLe X -BSA,glycan/conjugate,Q9NSU2,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,5.7e-11 M,-10.244,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,298.15,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,sLe X -BSA | 6.4 3 10 7 | 3.7 3 10 2 3 | 1.7 3 10 10 | 5.7 3 10 2 11,step2c_literal_v3
3,sLe X -BSA,glycan/conjugate,Q9NSU2,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,8.5e-11 M,-10.071,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,298.15,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,Clone 5 | 1.3 3 10 5 | 1.1 3 10 2 5 | 1.1 3 10 10 | 8.5 3 10 2 11,step2c_literal_v3
154,thrombin,protein,P00734,HD1-22,GGTTGGTGTGGTTGGAAAAAAAAAAAAGTCCGTGGTAGGGCAGGTTGGGGTGACT,6.5e-10 M,-9.187,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,bivalent fusion; poly-dA linker,18826387,10.1111/j.1538-7836.2008.03162.x,HD1-22 | Thrombin | K D ( M) | 6.5 · 10 ) 10,step2c_literal_v3
39,prothrombin,protein,P00734,RNAR9D-14T,GGCGGUCGAUCACACAGUUCAAACGUAAUAAGCCAAUGUACGAGGCAGACGACUCGCC,1.4 nM,-8.854,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,Hepes-saline buffer,,2'F-RNA,2' Fluorocytosine; 2' Fluorouracil,22385910,10.1111/j.1538-7836.2012.04679.x,"Compared with ARC-183, RNAR9D-14T has a >40-fold higher affinity for prothrombin ( K D RNAR9D-14T = 1.4 nM",step2c_literal_v3
30,thrombin,protein,P00734,HD22,AGTCCGTGGTAGGGCAGGTTGGGGTGACT,2.4e-09 M,-8.62,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,,18826387,10.1111/j.1538-7836.2008.03162.x,HD22 | Thrombin | K D ( M) | 2.4 · 10 ) 9,step2c_literal_v3
251,Human thrombin,protein,P00734,Pse08-29,TGACCTCTAGTGACTGATTTACGAGTC,2.6 nM,-8.585,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,Pse(08 - 29) | 1.33 10^6 | 3.47 10^-3 | 2.6,step2c_literal_v3
16,thrombin,protein,P00734,TBA,GGTTGGTGTGGTTGG,2.86e-09 M,-8.544,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,biotin at 3' end; six-carbon spacer,16053288,10.1021/ac0502450,thrombin | 2.2 10 5 | 6.3 10 - 4 | 3.4 10 8 | 2.86 10 - 9,step2c_literal_v3
11,sLe X,glycan/conjugate,Q9NSU2,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,3.3e-09 M,-8.481,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,sLe X | 1.7 3 10 5 | 5.5 3 10 2 4 | 3.0 3 10 8 | 3.3 3 10 2 9,step2c_literal_v3
156,prothrombin,protein,P00734,HD1,GGTTGGTGTGGTTGG,3.5e-09 M,-8.456,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,,18826387,10.1111/j.1538-7836.2008.03162.x,HD1 | Prothrombin+ phospholipids | K D ( M) | 3.5 · 10 ) 9,step2c_literal_v3
252,Mouse thrombin,protein,,Pse08-29,TGACCTCTAGTGACTGATTTACGAGTC,6.3 nM,-8.201,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,Pse(08 - 29) | 6.72 10^5 | 4.26 10^-3 | 6.3,step2c_literal_v3
28,thrombin,protein,P00734,HD1,GGTTGGTGTGGTTGG,7.1e-09 M,-8.149,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,,18826387,10.1111/j.1538-7836.2008.03162.x,HD1 | Thrombin | K D ( M) | 7.1 · 10 ) 9,step2c_literal_v3
194,α-thrombin,protein,P00734,TBA-iT7,GGTTGGTGTGGTTGG,9.9 nM,-8.004,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 7,30735210,10.1039/c9ob00053d,TBA-iT7 | 9.9,step2c_literal_v3
17,thrombin-HRP,protein,,TBA,GGTTGGTGTGGTTGG,1.13e-08 M,-7.947,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,biotin at 3' end; six-carbon spacer,16053288,10.1021/ac0502450,thrombin-HRP | 6.7 10 4 | 7.6 10 - 4 | 8.7 10 7 | 1.13 10 - 8,step2c_literal_v3
198,α-thrombin,protein,P00734,TBA-iT9,GGTTGGTGTGGTTGG,11.5 nM,-7.939,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 9,30735210,10.1039/c9ob00053d,TBA-iT9 | 11.5,step2c_literal_v3
196,α-thrombin,protein,P00734,TBA-G8-iT8,GGTTGGTTTGGTTGG,12.4 nM,-7.907,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 8,30735210,10.1039/c9ob00053d,TBA-G8-iT8 | 12.4,step2c_literal_v3
14,Le A,protein,P00488,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,1.4e-08 M,-7.854,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,Le A | 7.3 3 10 2 | 1.0 3 10 2 5 | 7.2 3 10 7 | 1.4 3 10 2 8,step2c_literal_v3
193,α-thrombin,protein,P00734,TBA-iT7,GGTTGGTGTGGTTGG,15.9 nM,-7.799,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 7,30735210,10.1039/c9ob00053d,TBA-iT7 | 15.9,step2c_literal_v3
12,sLe A,glycan/conjugate,P0C0L4,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,1.7e-08 M,-7.77,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,sLe A | 1.2 3 10 3 | 1.9 3 10 2 5 | 5.9 3 10 7 | 1.7 3 10 2 8,step2c_literal_v3
107,Mouse thrombin,protein,,TBA29,TGACCCTAGTGACTGATTTACGAGGTC,22.0 nM,-7.658,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,TBA29 | 2.76 10^5 | 6.07 10^-3 | 22.0,step2c_literal_v3
13,Le X,protein,O15496,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,2.4e-08 M,-7.62,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,Le X | 6.7 3 10 2 | 1.6 3 10 2 5 | 4.1 3 10 7 | 2.4 3 10 2 8,step2c_literal_v3
189,α-thrombin,protein,P00734,TBA,GGTTGGTGTGGTTGG,27.2 nM,-7.565,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,,30735210,10.1039/c9ob00053d,TBA | 27.2,step2c_literal_v3
141,PDGF-C,protein,P01127,α-PC,CTACTGTGTGATGTCTGAGAGCAGCGTCTAAACGAACAAGCGAACCTATGCACAGAGGACAGTACATCAGACAC,33.0 nM,-7.481,intrinsic,KD,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,7.4,"HBS-EP + (10-mM HEPES, 150-mM NaCl, 3-mM EDTA, and 0.05% Tween 20, pH 7.4)",,DNA,,42138517,10.1167/iovs.67.5.36,SPR analysis demonstrated that the α -PC aptamer bound tightly to mouse PDGF-C with a high affinity ( KD = 33 nM,step2c_literal_v3
192,α-thrombin,protein,P00734,TBA-iT3,GGTTGGTGTGGTTGG,33.9 nM,-7.47,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 3,30735210,10.1039/c9ob00053d,TBA-iT3 | 33.9,step2c_literal_v3
106,Human thrombin,protein,P00734,TBA29,TGACCCTAGTGACTGATTTACGAGGTC,36.9 nM,-7.433,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,TBA29 | 1.34 10^5 | 4.94 10^-3 | 36.9,step2c_literal_v3
200,α-thrombin,protein,P00734,TBA-iT12,GGTTGGTGTGGTTGG,37.0 nM,-7.432,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,3'-inverted thymidine at position 12,30735210,10.1039/c9ob00053d,TBA-iT12 | 37.0,step2c_literal_v3
195,α-thrombin,protein,P00734,TBA-G8-iT8,GGTTGGTTTGGTTGG,37.1 nM,-7.431,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 8,30735210,10.1039/c9ob00053d,TBA-G8-iT8 | 37.1,step2c_literal_v3
112,rmCD3 d ε -Fc,protein,,CD3_Apt5,CCTTGCCTGCTTTCACGTGTGATCCCTGCCCGT,37.9 nM,-7.421,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"PBS and 0.005% (v/v) Tween 20, pH 7.4",,2'F-RNA,2' Fluoropyrimidines,38745854,10.1016/j.omtn.2024.102198,aptamer 5 was the strongest binder (37.9 nM),step2c_literal_v3
197,α-thrombin,protein,P00734,TBA-iT9,GGTTGGTGTGGTTGG,41.0 nM,-7.387,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 9,30735210,10.1039/c9ob00053d,TBA-iT9 | 41.0,step2c_literal_v3
190,α-thrombin,protein,P00734,TBA,GGTTGGTGTGGTTGG,42.7 nM,-7.37,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,,100 mM KCl,,DNA,,30735210,10.1039/c9ob00053d,TBA | 42.7,step2c_literal_v3
199,α-thrombin,protein,P00734,TBA-iT12,GGTTGGTGTGGTTGG,46.8 nM,-7.33,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 12,30735210,10.1039/c9ob00053d,TBA-iT12 | 46.8,step2c_literal_v3
104,Human thrombin,protein,P00734,M08s,ACTGGAGATCACTGACTAAATGCTCCAG,47.2 nM,-7.326,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,M08s | 7.04 10^5 | 3.33 10^-2 | 47.2,step2c_literal_v3
191,α-thrombin,protein,P00734,TBA-iT3,GGTTGGTGTGGTTGG,57.3 nM,-7.242,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"138 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, and 1.76 mM KH2PO4, pH 7.4, 0.05% Tween-20",,DNA,3'-inverted thymidine at position 3,30735210,10.1039/c9ob00053d,TBA-iT3 | 57.3,step2c_literal_v3
51,CD63,protein,P08962,CD63 Aptamer,ACCACCCCACCTCGCTCCCGTGACACTAATGCTACTC,5.8e-08 M,-7.237,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,"HEPES buffer (10 mM HEPES, 150 mM NaCl)",,DNA,5' amine; 3' thiol; iSpC3 spacer; 3' thio modifier,26500145,10.1016/j.ymeth.2015.10.012,The equilibrium constant of the aptamer immobilized via 3 0 end was found to be KD = 5.8 -10  8 M.,step2c_literal_v3
40,prothrombin,protein,P00734,ARC-183,GGTTGGTGTGGTTGG,60.7 nM,-7.217,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,Hepes-saline buffer,,DNA,,22385910,10.1111/j.1538-7836.2012.04679.x,"Compared with ARC-183, RNAR9D-14T has a >40-fold higher affinity for prothrombin ( K D RNAR9D-14T = 1.4 nM and ARC-183 = 60.7 nM)",step2c_literal_v3
27,prothrombin,protein,P00734,HD1-22,GGTTGGTGTGGTTGGAAAAAAAAAAAAGTCCGTGGTAGGGCAGGTTGGGGTGACT,6.1e-08 M,-7.215,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,bivalent fusion; poly-dA linker,18826387,10.1111/j.1538-7836.2008.03162.x,HD1-22 | Prothrombin | K D ( M) | 6.1 · 10 ) 8,step2c_literal_v3
155,prothrombin,protein,P00734,HD1-22,GGTTGGTGTGGTTGGAAAAAAAAAAAAGTCCGTGGTAGGGCAGGTTGGGGTGACT,6.7e-08 M,-7.174,non_intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,bivalent fusion; poly-dA linker,18826387,10.1111/j.1538-7836.2008.03162.x,HD1-22 | Prothrombin+ phospholipids | K D ( M) | 6.7 · 10 ) 8,step2c_literal_v3
29,prothrombin,protein,P00734,HD1,GGTTGGTGTGGTTGG,7.8e-08 M,-7.108,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,,,,,DNA,,18826387,10.1111/j.1538-7836.2008.03162.x,HD1 | Prothrombin | K D ( M) | 7.8 · 10 ) 8,step2c_literal_v3
110,rmCD3 d ε -Fc,protein,,CD3_Apt1,CCCGATTGATTCGCAATGTGCGTCCCCTCGTGCC,91.3 nM,-7.04,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"PBS and 0.005% (v/v) Tween 20, pH 7.4",,2'F-RNA,2' Fluoropyrimidines,38745854,10.1016/j.omtn.2024.102198,aptamer 1 (91.3 nM),step2c_literal_v3
10,BSA,glycan/conjugate,O95870,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,1e-07 M,-7.0,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,BSA | 2.2 3 10 4 | 2.3 3 10 2 3 | 9.9 3 10 6 | 1.0 3 10 2 7,step2c_literal_v3
113,rmCD3 d ε -Fc,protein,,CD3_Apt12,TCCCCTGTCGATATCCACCGTCTGGCCCGCATTGA,206.0 nM,-6.686,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"PBS and 0.005% (v/v) Tween 20, pH 7.4",,2'F-RNA,2' Fluoropyrimidines,38745854,10.1016/j.omtn.2024.102198,aptamer 12 (206 nM),step2c_literal_v3
15,Lactose,protein,P00709,Clone 5,GGUGCAGGUCACUUCGAUGAGUGUAAAGCACAGGUAAGUGUCUUGGUAGAAUCGGAGUCGGUGACCGUU,2.9e-07 M,-6.538,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,KEEP_seq_in_figure,SPR,,7.4,"RNA binding buffer [150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2]",1.0,RNA,,11178986,10.1006/bbrc.2001.4327,Lactose | 6.3 3 10 2 | 1.8 3 10 2 4 | 3.4 3 10 6 | 2.9 3 10 2 7,step2c_literal_v3
111,rmCD3 d ε -Fc,protein,,CD3_Apt3,TCCCTACCTGAAACTCGAAGATGAGCCCTGTCTGA,430.0 nM,-6.367,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.15,7.4,"PBS and 0.005% (v/v) Tween 20, pH 7.4",,2'F-RNA,2' Fluoropyrimidines,38745854,10.1016/j.omtn.2024.102198,aptamer 3 (430 nM),step2c_literal_v3
105,Mouse thrombin,protein,,M08s,ACTGGAGATCACTGACTAAATGCTCCAG,495.0 nM,-6.305,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,backfill_text_verified,KEEP_seq_in_figure,SPR,,7.4,"PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20",,DNA,,37621412,10.1016/j.omtn.2023.07.038,M08s | 3.56 10^5 | 1.76 10^-1 | 495,step2c_literal_v3
45,IL-8,protein,P10145,8A-30,GGGUUAUCAUUCCAUUUAGUGUUAUGAUAA,1.22e-06 M,-5.914,intrinsic,Kd,Gold,v4,extraction_verified,verified_in_text_or_SI,original,,SPR,298.0,7.4,"HBST running buffer (10 mM HEPES, pH 7.4, 150 mM NaCl, and 0.005% Tween 20)",,2'F-RNA,2'-fluoro-pyrimidine modified,24129312,10.1016/j.biomaterials.2013.09.107,| 8A-30       | 1.32 x 10 6 | 1.62         | 1.22 x 10 -6  | 4.62 x 10 -5 | 1.06 x 10 -3 |,step2c_literal_v3