id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
302,prostate-cancer-derived small extracellular vesicles,cell/EV,Q99523,seq25,,24.02 nM,-7.619,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,SPR,,,PBST buffer,,DNA,5'-FAM,41646885,10.1016/j.omtn.2026.102836,"The affinity of seq25 for positive selection was significantly higher than that of the other aptamers, with a KD of 24.02 nM",step2c_literal_v3