id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
406,SARS-CoV-2 spike protein (wild type),protein,,DSA1N5,,3e-12 M,-11.523,avidity_multivalent,Kd,Gold,v4,multi_agent_verified,pending_manual_supp,,,dot_blot,,,undiluted wastewater,,DNA,dimeric,36926840,10.1021/acssensors.2c02655,"DSA1N5 also demonstrated high binding affinity in undiluted wastewater samples ( K d = 3.0 -3.9 pM for WTPV, Figure S1A,B).",step2c_acs_v1
743,SARS-CoV-2 spike protein (wild type),protein,,DSA1N5,,3.9e-12 M,-11.409,avidity_multivalent,Kd,Gold,ACS,multi_agent_verified,pending_manual_supp,,,dot_blot,,,undiluted wastewater,,DNA,dimeric,36926840,10.1021/acssensors.2c02655,"DSA1N5 also demonstrated high binding affinity in undiluted wastewater samples ( K d = 3.0 -3.9 pM for WTPV, Figure S1A,B).",step2c_acs_v1
404,SARS-CoV-2 pseudotyped lentivirus (omicron variant),protein,,DSA1N5,,4.8e-12 M,-11.319,avidity_multivalent,Kd,Gold,v4,multi_agent_verified,pending_manual_supp,,,dot_blot,,,deionized water,,DNA,dimeric,36926840,10.1021/acssensors.2c02655,"This study demonstrates that DSA1N5 has high affinity for recognizing OMPV with a K d value of 4.8 pM, which is in the same order of magnitude as that measured for the WTPV (2.1 pM) in deionized water (DI water)",step2c_acs_v1
405,SARS-CoV-2 pseudotyped lentivirus (omicron variant),protein,,DSA1N5,,5.1e-12 M,-11.292,avidity_multivalent,Kd,Gold,v4,multi_agent_verified,pending_manual_supp,,,dot_blot,,,wastewater (diluted 50% with binding buffer),,DNA,dimeric,36926840,10.1021/acssensors.2c02655,DSA1N5 preserves its binding affinity in 50% wastewater ( K d = 2.1 -4.1 pM for WTPV and 5.1 for OMPV in wastewater).,step2c_acs_v1