id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
202,CD8a,protein,P01732,A3,,1.9 nM,-8.721,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers have apparent K D values of 18.3 ± 4.6, 1.9 ± 0.8 and 2.4 ± 0.9  nM, respectively",step2c_literal_v3
203,CD8a,protein,P01732,A8,,2.4 nM,-8.62,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers have apparent K D values of 18.3 ± 4.6, 1.9 ± 0.8 and 2.4 ± 0.9  nM, respectively",step2c_literal_v3
226,transferrin receptor 1,protein,P02786,JBA8.26,,3.3 nM,-8.481,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,35875870,10.1021/jacs.2c05349,JBA8.26 bound TfR1 hi H9 T-lymphoma cells with an apparent K D of 3.3 ± 0.6 nM,step2c_literal_v3
224,transferrin receptor 1,protein,P02786,JBA8.1,,5.5 nM,-8.26,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,fluorescein-labeled,35875870,10.1021/jacs.2c05349,JBA8.1 has an apparent binding affinity (K D ) of 5.5 ± 1.2 nM,step2c_literal_v3
225,transferrin receptor 1,protein,P02786,tJBA8.1,,10.9 nM,-7.963,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,35875870,10.1021/jacs.2c05349,versus that of 10.9 ± 2.4 nM for tJBA8.1,step2c_literal_v3
201,CD8a,protein,P01732,A1,,18.3 nM,-7.738,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,31209354,10.1038/s41551-019-0411-6,"the A1, A3 and A8 aptamers have apparent K D values of 18.3 ± 4.6, 1.9 ± 0.8 and 2.4 ± 0.9  nM, respectively",step2c_literal_v3
227,transferrin receptor 1,protein,P02786,tJBA8.1,,25.6 nM,-7.592,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,,,,,DNA,,35875870,10.1021/jacs.2c05349,compared to tJBA8.1's apparent K D of 25.6 ± 13.0 nM for these cells,step2c_literal_v3
222,CD20,protein,P11836,WB1-CD20,,73.0 nM,-7.137,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,298.15,,Cell Suspension Buffer (CSB),,DNA,5'-FAM,35829681,10.1021/acs.biochem.2c00105,"The apparent affinities of WB1-CD20 and WB2-CD20 were calculated as 73 nM and 163 nM at 25°C, respectively",step2c_literal_v3
220,CD19,protein,P15391,WB15-CD19,,153.0 nM,-6.815,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,298.15,,Cell Suspension Buffer (CSB),,DNA,5'-FAM,35829681,10.1021/acs.biochem.2c00105,"At 25 °C, WB15-CD19 showed an apparent affinity of 153 nM",step2c_literal_v3
223,CD20,protein,P11836,WB2-CD20,,163.0 nM,-6.788,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,298.15,,Cell Suspension Buffer (CSB),,DNA,5'-FAM,35829681,10.1021/acs.biochem.2c00105,"The apparent affinities of WB1-CD20 and WB2-CD20 were calculated as 73 nM and 163 nM at 25°C, respectively",step2c_literal_v3
221,CD19,protein,P15391,WB17-CD19,,187.0 nM,-6.728,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,298.15,,Cell Suspension Buffer (CSB),,DNA,5'-FAM,35829681,10.1021/acs.biochem.2c00105,and WB17-CD19 showed an apparent affinity of 187 nM (Figure S12A-B).,step2c_literal_v3
263,H-6 cells,cell/EV,O14756,Apta25,,0.42 µM,-6.377,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,H-6 cells showed binding with Apta25 ( K D value-0.42 ± 0.093 µ m),step2c_literal_v3
261,K-1 cells,cell/EV,O60814,Apta30,,0.66 µM,-6.18,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,Apta30 ( K D -0.66 ± 0.12 µ m),step2c_literal_v3
264,H-6 cells,cell/EV,O14756,Apta30,,1.107 µM,-5.956,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,H-6 cells showed binding with ... Apta30 ( K D -1.107 ± 0.208 µ m),step2c_literal_v3
262,K-1 cells,cell/EV,O60814,Apta25,,1.358 µM,-5.867,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,Apta25 ( K D value-1.358 ± 0.201 µ m),step2c_literal_v3
259,K-1 cells,cell/EV,O60814,Apta02,,1.821 µM,-5.74,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,Apta02 ( K D value-1.821 ± 0.117 µ m),step2c_literal_v3
260,K-1 cells,cell/EV,O60814,Apta04,,1.867 µM,-5.729,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,Apta04 ( K D value-1.867 ± 0.19 µ m),step2c_literal_v3
265,H-9 cells,cell/EV,Q8IVB4,Apta02,,4.93 µM,-5.307,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,H-9 cells showed binding with Apta02 ( K D value-4.93 ± 0.367 µ m),step2c_literal_v3
266,H-9 cells,cell/EV,Q8IVB4,Apta04,,5.402 µM,-5.267,non_intrinsic,Kd,Gold,v4,extraction_verified,pending_supp_oa,,,flow_cytometry,310.15,,,,DNA,,40487293,10.1002/adfm.202425394,H-9 cells showed binding with ... Apta04 ( K D value-5.402 ± 0.795 µ m),step2c_literal_v3