id,target_name_canonical,target_type,target_uniprot,aptamer_name,aptamer_seq,kd_reported,kd_log10_molar,measurement_class,binding_constant_type,tier,source_origin,verification_level,sequence_status,seq_source,pi_provenance_flag,assay_method,assay_temperature_k,assay_ph,assay_buffer,assay_cations,aptamer_chemistry,aptamer_modifications,source_pmid,doi,verbatim_quote,source_db
336,VEGF-165,protein,P15692,bivalent construct for VEGF-165 (no linker),,1.7e-08 M,-7.77,avidity_multivalent,Kd,Gold,v4,multi_agent_verified,pending_manual_figure,,,,,,,,,,27043498,10.3390/molecules21040421,this bivalent construct had about 28-fold higher binding affinity ( K D = 17 nM),step2c_acs_v1