{"database": "scout", "table": "v_kd", "is_view": true, "human_description_en": "where assay_method = \"BLI\" and sequence_status = \"pending_supp_oa\" sorted by kd_log10_molar", "rows": [[63, "CD8a", "protein", "P01732", "A8", null, "5.59 nM", -8.253, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [87, "transferrin receptor 1", "protein", "P02786", "JBA8.26", null, "6.87 nM", -8.163, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", null, null, null, null, "DNA", null, "35875870", "10.1021/jacs.2c05349", "Using BLI, JBA8.26 was found to bind immobilized TfR1 with a K D of 6.87 \u00b1 0.04 nM", "step2c_literal_v3"], [62, "CD8a", "protein", "P01732", "A3", null, "14.7 nM", -7.833, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [61, "CD8a", "protein", "P01732", "A1", null, "20.1 nM", -7.697, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [128, "CD117", "protein", "P10721", "Apta02", null, "21.8 nM", -7.662, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 \u00b5 m, respectively ( Figure 2 a,b).", "step2c_literal_v3"], [86, "transferrin receptor 1", "protein", "P02786", "tJBA8.1", null, "25.11 nM", -7.6, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", null, null, null, null, "DNA", "biotinylated", "35875870", "10.1021/jacs.2c05349", "tJBA8.1 bound the TfR1 protein with a K D value of 25.11 \u00b1 0.19 nM", "step2c_literal_v3"], [129, "CD117", "protein", "P10721", "Apta04", null, "1100.0 nM", -5.959, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 \u00b5 m, respectively ( Figure 2 a,b).", "step2c_literal_v3"], [131, "CD123", "protein", "O75794", "Apta25", null, "1.16 \u00b5M", -5.936, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 \u00b5 m for ZW25 and 15.6 \u00b5 m for CY30 (Figure S2, Supporting Information).", "step2c_literal_v3"], [130, "CD123", "protein", "O75794", "Apta30", null, "15.6 \u00b5M", -4.807, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 \u00b5 m for ZW25 and 15.6 \u00b5 m for CY30 (Figure S2, Supporting Information).", "step2c_literal_v3"]], "truncated": false, "filtered_table_rows_count": 9, 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Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}