{"database": "scout", "table": "v_kd", "is_view": true, "human_description_en": "where assay_method = \"QCM\", sequence_status = \"verified_in_text_or_SI\" and tier = \"Gold\" sorted by kd_log10_molar", "rows": [[343, "PlanarAu", "protein", null, "1N", "TATGCATGTGTAGTAAGACCTAGTCCACAATCAACG", "5.600000000000001e-10 M", -9.252, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, "AIB", null, "DNA", null, "30189130", "10.1021/acscombsci.8b00048", "aptamer 1N showing the highest affinity (0.56 nM)", "step2c_acs_v1"], [59, "RAGE", "protein", "P80511", "RAGE-aptamer (clone #2)", "TCTGTTCAGGTTGGTACGGTGGAAGGTGTGATTCACGAGG", "4.44 nM", -8.353, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, null, null, "DNA", "phosphorothioate", "28385802", "10.2337/db16-1281", "#2RAGE-aptamer | tcTgTTcAggTTggTAcggTggAAggTgTgATTcAcgAgg | 4.44\u00b10.56", "step2c_literal_v3"], [58, "RAGE", "protein", "P80511", "RAGE-aptamer (clone #1)", "CCTGATATGGTGTCACCGCCGCCTTAGTATTGGTGTCTAC", "5.68 nM", -8.246, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, null, null, "DNA", "phosphorothioate", "28385802", "10.2337/db16-1281", "#1RAGE-aptamer | ccTgATATggTgTcAccgccgccTTAgTATTggTgTcTAc | 5.68\u00b11.10", "step2c_literal_v3"], [60, "RAGE", "protein", "P80511", "RAGE-aptamer (clone #3)", "TTCCACTGAGTGCCGCGGACTGTTGTTGGGAGGTGGTGTG", "12.44 nM", -7.905, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, null, null, "DNA", "phosphorothioate", "28385802", "10.2337/db16-1281", "#3RAGE-aptamer | tTccAcTgAgTgccgcggAcTgTTgTTgggAggTggTgTg | 12.44\u00b11.52", "step2c_literal_v3"], [344, "PlanarAu", "protein", null, "1N truncated", "TATGCATGTGTATATCAACACTCCGGGTCTAATCGTTCA", "1.304e-08 M", -7.885, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, "AIB", null, "DNA", null, "30189130", "10.1021/acscombsci.8b00048", "1N truncated (Kd = 13.04 nM)", "step2c_acs_v1"], [19, "thrombin", "protein", "P00734", "LOOP", "GGTTGGTGTGGTTGGCAACC", "39.0 nM", -7.409, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "verified_in_text_or_SI", "original", null, "QCM", null, 7.4, "140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 20 mM TRIS, pH 7.4", "1.0", "DNA", "biotin at 3' end", "16725379", "10.1016/j.bioelechem.2006.03.012", "LOOP | 3.27\u00b11.22 | 127\u00b1100 | 0.026\u00b10.018 | 39\u00b127", "step2c_literal_v3"], [18, "thrombin", "protein", "P00734", "APTA", "GGGTTTTCACTTTTGTGGGTTGGACGGGATGG", "88.0 nM", -7.056, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "verified_in_text_or_SI", "original", null, "QCM", null, 7.4, "140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 20 mM TRIS, pH 7.4", "1.0", "DNA", "biotin at 3' end", "16725379", "10.1016/j.bioelechem.2006.03.012", "APTA | 0.97\u00b10.45 | 86\u00b173 | 0.011\u00b10.006 | 88\u00b152", "step2c_literal_v3"]], "truncated": false, "filtered_table_rows_count": 7, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "target_name_canonical", "target_type", "target_uniprot", "aptamer_name", "aptamer_seq", "kd_reported", "kd_log10_molar", "measurement_class", "binding_constant_type", "tier", "source_origin", "verification_level", "sequence_status", "seq_source", "pi_provenance_flag", "assay_method", "assay_temperature_k", "assay_ph", "assay_buffer", "assay_cations", "aptamer_chemistry", "aptamer_modifications", "source_pmid", "doi", "verbatim_quote", "source_db"], "primary_keys": [], "units": {}, "query": {"sql": "select id, target_name_canonical, target_type, target_uniprot, aptamer_name, aptamer_seq, kd_reported, kd_log10_molar, measurement_class, binding_constant_type, tier, source_origin, verification_level, sequence_status, seq_source, pi_provenance_flag, assay_method, assay_temperature_k, assay_ph, assay_buffer, assay_cations, aptamer_chemistry, aptamer_modifications, source_pmid, doi, verbatim_quote, source_db from v_kd where \"assay_method\" = :p0 and \"sequence_status\" = :p1 and \"tier\" = :p2 order by kd_log10_molar limit 51", "params": {"p0": "QCM", "p1": "verified_in_text_or_SI", "p2": "Gold"}}, "facet_results": {"measurement_class": {"name": "measurement_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "intrinsic", "label": "intrinsic", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&measurement_class=intrinsic", "selected": false}], "truncated": false}, "target_type": {"name": "target_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "protein", "label": "protein", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&target_type=protein", "selected": false}], "truncated": false}, "tier": {"name": "tier", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "Gold", "label": "Gold", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI", "selected": true}], "truncated": false}, "assay_method": {"name": "assay_method", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "QCM", "label": "QCM", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=verified_in_text_or_SI&tier=Gold", "selected": true}], "truncated": false}, "binding_constant_type": {"name": "binding_constant_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "Kd", "label": "Kd", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&binding_constant_type=Kd", "selected": false}], "truncated": false}, "verification_level": {"name": "verification_level", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "extraction_verified", "label": "extraction_verified", "count": 5, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&verification_level=extraction_verified", "selected": false}, {"value": "multi_agent_verified", "label": "multi_agent_verified", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&verification_level=multi_agent_verified", "selected": false}], "truncated": false}, "sequence_status": {"name": "sequence_status", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold", "results": [{"value": "verified_in_text_or_SI", "label": "verified_in_text_or_SI", "count": 7, "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&tier=Gold", "selected": true}], "truncated": false}}, "suggested_facets": [{"name": "target_name_canonical", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=target_name_canonical"}, {"name": "target_uniprot", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=target_uniprot"}, {"name": "assay_buffer", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=assay_buffer"}, {"name": "aptamer_modifications", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=aptamer_modifications"}, {"name": "source_pmid", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=source_pmid"}, {"name": "doi", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=doi"}, {"name": "source_db", "toggle_url": "https://apt-scout.org/scout/v_kd.json?assay_method=QCM&sequence_status=verified_in_text_or_SI&tier=Gold&_facet=source_db"}], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 63.69247194379568, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}