{"database": "scout", "table": "v_kd", "is_view": true, "human_description_en": "where measurement_class = \"intrinsic\", sequence_status = \"pending_manual_supp\" and verification_level = \"multi_agent_verified\" sorted by kd_log10_molar", "rows": [[478, "FLRPp (O serotype)", "protein", null, "FMD_1", null, "3.46e-10 M", -9.461, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", null, null, null, null, "DNA", null, "42010751", "10.1021/acs.analchem.5c04748", "dissociation constants ( KD ) of 3.46 \u00d7 10 -10 M", "step2c_acs_v1"], [459, "PSMA", "protein", "Q04609", "C3", null, "8.000000000000001e-10 M", -9.097, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "EMSA", null, null, "5 mM Mg2+", null, "DNA", "phenol-dT; naphthyl-dC; PSMA-617 bait", "41126016", "10.1021/jacs.5c13307", "an exemplar shows very high affinity for PSMA ( K d \u223c 0.8 nM).", "step2c_acs_v1"], [458, "PSMA", "protein", "Q04609", "C3 (without fluorescein)", null, "1e-09 M", -9.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "EMSA", null, null, null, null, "DNA", "phenol-dT; naphthyl-dC; Cy5 label", "41126016", "10.1021/jacs.5c13307", "EMSA data show that Cy5-labeled C3 without fluorescein binds PSMA just as strongly as the parent construct, with an apparent K d of \u223c 1 nM (Figure S9).", "step2c_acs_v1"], [337, "human \u03b1-thrombin", "protein", "P00734", "LOOPER modified thrombin aptamer", null, "1.6000000000000003e-09 M", -8.796, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", null, null, null, null, "DNA", "diversely functionalized; heteromultivalent", "28938065", "10.1021/jacs.7b07241", "Using single-cycle kinetics surface plasmon resonance (SPR), the LOOPER aptamer exhibited a Kd of 1.6 nM", "step2c_acs_v1"], [316, "CD44-HABD", "protein", null, "Motif 4 (ADDA adduct)", null, "2e-09 M", -8.699, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23057694", "10.1021/bi300471d", "motifs 2 and 4(ADDA adduct) have ~2 nM affinity to CD44-HABD", "step2c_acs_v1"], [322, "S-adenosylmethionine", "protein", "P17707", "Bs SAM-I riboswitch", null, "3.0000000000000004e-09 M", -8.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23343213", "10.1021/ja310742m", "Both \u03bc MSA values agree well with results from the in-line probing assays performed using identical buffer conditions: ... 3 nM K d , respectively", "step2c_acs_v1"], [323, "S-adenosylmethionine", "protein", "P17707", "Pi SAM-I riboswitch", null, "3.0000000000000004e-09 M", -8.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23343213", "10.1021/ja310742m", "which is on the order of the 3 nM value measured using a conventional inline probing assay", "step2c_acs_v1"], [338, "human \u03b1-thrombin", "protein", "P00734", "LOOPER modified thrombin aptamer", null, "4e-09 M", -8.398, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "28938065", "10.1021/jacs.7b07241", "Preliminary binding analysis by label-free microscale thermophoresis showed a promising dissociation constant K d = 4 nM for thrombin", "step2c_acs_v1"], [461, "Lipopolysaccharide from Klebsiella pneumoniae ATCC 15380", "protein", null, "aptamer seq. 5", null, "6.68e-09 M", -8.175, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "DPV", null, null, "1 \u00d7 PBS", null, "DNA", "biotin", "41323700", "10.1039/d5ra06759f", "The binding affinity of aptamer seq. 5 was 6.68 nM (Fig. 9C).", "step2c_acs_v1"], [348, "NP", "protein", "Q16612", "NP-C04", null, "8.1e-09 M", -8.092, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.4, "20 mM HEPES, 150 mM NaCl, 2 mM KCl, 2 mM MgCl2, and 2 mM CaCl2 (pH 7.4)", null, "DNA", "FAM", "30740973", "10.1021/acs.analchem.8b04623", "the K d values of NP-D01, NP-C04, and NP-D02 were 76..1 \u00b1 10.9, 8.1 \u00b1 2.4, and 41.3 \u00b1 9.5 nM, respectively.", "step2c_acs_v1"], [423, "TAR RNA", "protein", "Q13395", "TAR RNA aptamer (best binding)", null, "9.000000000000001e-09 M", -8.046, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "39167715", "10.1021/jacs.4c08824", "A Biolayer Interferometry (BLI) experiment revealed that TAR RNA aptamers with the best binding affinity exhibited the dissociation constant ( K D) at 9 nM", "step2c_acs_v1"], [345, "streptavidin", "protein", null, "S8", null, "1e-08 M", -8.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "30520292", "10.1021/acssensors.8b00945", "At pH 7.4, we determined that S8 has a K d of 10 nM", "step2c_acs_v1"], [366, "trastuzumab", "protein", "Q9ULR3", "CH1S-3", null, "1.0300000000000001e-08 M", -7.987, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "MST", 298.15, null, "washing bu ff er with the addition of 0.005% Tween 20", null, "DNA", "5'-Cy5", "32516525", "10.1021/jacs.9b13370", "a ffi nity with a K d value of aptamer CH1S-3 of 10.3 nM", "step2c_acs_v1"], [334, "17 \u03b2 -Estradiol", "protein", "P42167", "22-mer aptamer", null, "1.1000000000000001e-08 M", -7.959, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "25803717", "10.1021/acs.analchem.5b00335", "new 35-mer and 22-mer aptamers were generated with K D ' s of 14 and 11 nM", "step2c_acs_v1"], [333, "17 \u03b2 -Estradiol", "protein", "P42167", "35-mer aptamer", null, "1.4000000000000001e-08 M", -7.854, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "25803717", "10.1021/acs.analchem.5b00335", "new 35-mer and 22-mer aptamers were generated with K D ' s of 14 and 11 nM", "step2c_acs_v1"], [314, "hMMP-9", "protein", null, "F3Bomf", null, "2e-08 M", -7.699, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", 296.15, null, "PBS buffer", null, "2'-OMe-RNA", "2'-O-methyl purine; 2'-fluoro pyrimidine; 5'-hexylamino linker; 5'-MAG3 conjugate", "23043415", "10.1021/bc300146c", "The K d was taken as the concentration leading to half saturation, i.e., about 20 nM.", "step2c_acs_v1"], [315, "hMMP-9", "protein", null, "F3", null, "2e-08 M", -7.699, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, "2'F-RNA", "2'-fluoro pyrimidine ribonucleosides", "23043415", "10.1021/bc300146c", "exhibits a strong a ffi nity for hMMP-9 ( K d = 20 nM)", "step2c_acs_v1"], [480, "NMP22", "protein", "Q14980", "NT2a", null, "2.4260000000000003e-08 M", -7.615, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "MST", null, null, null, null, "DNA", "biotin", "42173503", "10.1021/acs.analchem.6c00738", "The K d values were also determined using MicroScale Thermophoresis (MST), and the K d values of NT2a and NT4a were determined to be 24.26 \u00b1 10.47 and 77.29 \u00b1 25.78 nM (Figures 2d and S3).", "step2c_acs_v1"], [321, "S-adenosylmethionine", "protein", "P17707", "Bs SAM-I riboswitch", null, "2.5000000000000002e-08 M", -7.602, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23343213", "10.1021/ja310742m", "Both \u03bc MSA values agree well with results from the in-line probing assays performed using identical buffer conditions: 25 nM K d ", "step2c_acs_v1"], [424, "verrucarin A", "protein", null, "Ver1_JYP", null, "2.9500000000000003e-08 M", -7.53, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.4, "SELEX buffer", null, "DNA", null, "39404132", "10.1021/acs.analchem.4c03307", "The novel ssDNA aptamer exhibited a binding affinity of 29.5 nM", "step2c_acs_v1"], [325, "L-TAR RNA", "protein", "Q13395", "D-6-4t", null, "3.0000000000000004e-08 M", -7.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23977945", "10.1021/ja406634g", "The Kd of in vitro transcribed D-6-4t for L-TAR is 30 nM", "step2c_acs_v1"], [353, "Thrombin", "protein", "P00734", "Antithrombin aptamer", null, "3.3000000000000004e-08 M", -7.481, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "31580650", "10.1021/acs.analchem.9b00081", "Antithrombin aptamer with KD of 33 nM was successfully isolated by four rounds of MCP-SELEX.", "step2c_acs_v1"], [354, "paramylon", "protein", null, "Par-15", null, "3.49e-08 M", -7.457, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.5, "binding buffer (50 mM Tris, 150 mM NaCl, 5 mM MgCl2, 1 mM EDTA, pH 7.5)", null, "DNA", "FAM", "31809034", "10.1021/acs.jafc.9b04588", "The estimated K d values of fi ve selected aptamers, Par-7, Par-15, Par-18, Par-20, and Par-22, are 17.45 \u00b1 2.61, 34.90 \u00b1 5.83, 64.06 \u00b1 6.72, 123.81 \u00b1 13.41, and 249.52 \u00b1 46.39 nM, respectively.", "step2c_acs_v1"], [311, "HAP 1b", "protein", null, "Aptamer 21", null, "5.0000000000000004e-08 M", -7.301, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "21899290", "10.1021/nn2006927", "A high-affinity RNA aptamer (K d  = 50 nM) was efficiently identified by SELEX against a heteroaryl dihydropyrimidine structure", "step2c_acs_v1"], [355, "paramylon", "protein", null, "Par-18", null, "6.406e-08 M", -7.193, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.5, "binding buffer (50 mM Tris, 150 mM NaCl, 5 mM MgCl2, 1 mM EDTA, pH 7.5)", null, "DNA", "FAM", "31809034", "10.1021/acs.jafc.9b04588", "The estimated K d values of fi ve selected aptamers, Par-7, Par-15, Par-18, Par-20, and Par-22, are 17.45 \u00b1 2.61, 34.90 \u00b1 5.83, 64.06 \u00b1 6.72, 123.81 \u00b1 13.41, and 249.52 \u00b1 46.39 nM, respectively.", "step2c_acs_v1"], [400, "6'-sialyllactose", "protein", "Q9Y3R4", "Apt9-1", null, "9.175000000000001e-08 M", -7.037, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 298.15, 7.4, "10 mM PBS (pH 7.4)", null, "DNA", null, "36700646", "10.1021/acs.jafc.2c07784", "A 35 nt truncated aptamer Apt9-1 ( K d = 91.75 nM) with higher affinity than Apt9 was finally obtained.", "step2c_acs_v1"], [420, "17 \u03b2 -estradiol", "protein", "P42167", "HEV1", null, "9.276e-08 M", -7.033, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "MST", null, 7.6, "20 mM Tris (pH 7.6), 300 mM NaCl, 5 mM MgCl2, 0.01% Tween 20", null, "DNA", null, "38276613", "10.3390/molecules29020535", "the dissociation constant (KD value) is 92.76 \u00b1 66.02 nM as calculated by the calculation function that comes with the system.", "step2c_acs_v1"], [324, "D-TAR RNA", "protein", "Q9Y5S9", "L-6-4t", null, "1.0000000000000001e-07 M", -7.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23977945", "10.1021/ja406634g", "the K d  of the L-aptamer for D-TAR RNA is 100 nM", "step2c_acs_v1"], [436, "SIRT2", "protein", "Q8IXJ6", "Apt 45", null, "1.233e-07 M", -6.909, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 310.15, null, null, null, "DNA", "FAM", "40200675", "10.1021/acs.analchem.5c00066", "selected Apt 45 ( K d = 123.3 nM) to fabricate the 'turn-on' fluorescent biosensor", "step2c_acs_v1"], [399, "6'-sialyllactose", "protein", "Q9Y3R4", "Apt9", null, "1.5230000000000003e-07 M", -6.817, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 298.15, 7.4, "10 mM PBS (pH 7.4)", null, "DNA", null, "36700646", "10.1021/acs.jafc.2c07784", "The ssDNA aptamer Apt9 ( K d = 152.3 nM) with a length of 79 nucleotides (nt) was demonstrated as the optimal aptamer candidate", "step2c_acs_v1"], [326, "D-TAR RNA", "protein", "Q9Y5S9", "L-6-4t", null, "1.6e-07 M", -6.796, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23977945", "10.1021/ja406634g", "The L-6-4t aptamer has somewhat reduced affinity for D-TAR RNA under the low-salt conditions (K d  = 160 nM)", "step2c_acs_v1"], [369, "Cd2+", "protein", "P06729", "probe", null, "2.2e-07 M", -6.658, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "32618180", "10.1021/acs.analchem.0c01710", "the disassociation constant ( K D) between Cd 2+ and its aptamer were calculated to be 96 M -1 S -1 , 2.11 \u00d7 10 -5 S -1 , and 220 nM, respectively", "step2c_acs_v1"], [467, "benzovindiflupyr", "protein", null, "Apt.BZF01", null, "2.2650000000000002e-07 M", -6.645, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, null, null, null, "DNA", null, "41614999", "10.1021/acs.jafc.5c15044", "corrected KDs of 226.5 nM (Apt.BZF01)", "step2c_acs_v1"], [425, "verrucarin A", "protein", null, "14_Ver1", null, "2.2e-06 M", -5.658, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.4, "SELEX buffer", null, "DNA", "6-FAM at 5'-end; dabcyl at 3'-end", "39404132", "10.1021/acs.analchem.4c03307", "The binding test demonstrated that the decrease in fluorescence was correlated with increasing verrucarin A concentration with K D = 2.2 \u03bcM.", "step2c_acs_v1"], [426, "verrucarin A", "protein", null, "Ver1_JYP (C32G mutant)", null, "2.2999999999999996e-06 M", -5.638, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.4, "SELEX buffer", null, "DNA", "C32G mutation", "39404132", "10.1021/acs.analchem.4c03307", "guanine with both functional groups exhibited partially recovered binding activity ( K D = 2.3 \u03bcM).", "step2c_acs_v1"], [462, "Patulin", "protein", null, "PTL-1", null, "1.2499999999999999e-05 M", -4.903, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "ITC", 298.15, 6.0, "selection buffer (10 mM MES, pH 6.0, 150 mM NaCl, 5 mM MgCl2)", null, "DNA", null, "41473783", "10.1186/s44280-025-00101-2", "The measured K d from ITC value was 12.5 \u03bcM", "step2c_acs_v1"], [463, "Patulin", "protein", null, "PTL-1", null, "1.8399999999999997e-05 M", -4.735, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 6.0, "selection buffer (10 mM MES, pH 6.0, 150 mM NaCl, 5 mM MgCl2)", null, "DNA", null, "41473783", "10.1186/s44280-025-00101-2", "yielding an apparent K d of 18.4 \u03bcM", "step2c_acs_v1"], [388, "patulin", "protein", null, "PAT Rep", null, "4e-05 M", -4.398, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", null, null, "PBS", null, "DNA", "5' biotin", "35546052", "10.1021/acs.jafc.2c01591", "PAT Rep showed a K D value of 4.0 \u00d7 10 -5 M", "step2c_acs_v1"], [464, "Patulin", "protein", null, "PAT-6", null, "4.8e-05 M", -4.319, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 6.0, "20 mM MES buffer, pH = 6.0, with 150 mM NaCl and 2.0 mM MgCl2", null, "DNA", null, "41473783", "10.1186/s44280-025-00101-2", "PAT-6 has weaker binding affinities ( Kd = 48 \u03bcM by ThT, Fig. 4S)", "step2c_acs_v1"], [470, "L-lactate", "protein", "Q9BYZ2", "Lac2059", null, "0.00011 M", -3.959, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "ITC", 298.15, null, "SELEX buffer", null, "DNA", null, "41779931", "10.1021/acs.analchem.5c07149", "The K d from ITC was determined to be 0.11 mM", "step2c_acs_v1"], [471, "L-lactate", "protein", "Q9BYZ2", "Lac201", null, "0.0009000000000000001 M", -3.046, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 296.15, null, "SELEX buffer", null, "DNA", "2AP", "41779931", "10.1021/acs.analchem.5c07149", "the fitted K d was 0.9 mM (Figure 5C, black line)", "step2c_acs_v1"], [457, "Tris(hydroxymethyl)aminomethane", "protein", null, "Tris aptamer", null, "0.0026000000000000003 M", -2.585, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, null, null, null, "DNA", null, "40905906", "10.1021/acs.analchem.5c03351", "ThT yielded K d values changed modestly from 1.6 to 2.6 mM", "step2c_acs_v1"], [473, "L-lactate", "protein", "Q9BYZ2", "Lac2059", null, "0.0033 M", -2.481, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 296.15, null, "SELEX buffer", null, "DNA", "2AP", "41779931", "10.1021/acs.analchem.5c07149", "The fitted K d was 3.3 mM for this 2AP-labeled aptamer", "step2c_acs_v1"], [472, "L-lactate", "protein", "Q9BYZ2", "Lac201", null, "0.0043 M", -2.367, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", 296.15, null, "SELEX buffer", null, "DNA", "2AP", "41779931", "10.1021/acs.analchem.5c07149", "although the obtained K d (4.3 mM) was about 5-fold higher than that obtained using Mg 2+ .", "step2c_acs_v1"]], "truncated": false, "filtered_table_rows_count": 44, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "target_name_canonical", "target_type", "target_uniprot", "aptamer_name", "aptamer_seq", "kd_reported", "kd_log10_molar", "measurement_class", "binding_constant_type", "tier", "source_origin", "verification_level", "sequence_status", "seq_source", "pi_provenance_flag", "assay_method", "assay_temperature_k", "assay_ph", "assay_buffer", "assay_cations", "aptamer_chemistry", "aptamer_modifications", "source_pmid", "doi", "verbatim_quote", "source_db"], "primary_keys": [], "units": {}, "query": {"sql": "select id, target_name_canonical, target_type, target_uniprot, aptamer_name, aptamer_seq, kd_reported, kd_log10_molar, measurement_class, binding_constant_type, tier, source_origin, verification_level, sequence_status, seq_source, pi_provenance_flag, assay_method, assay_temperature_k, assay_ph, assay_buffer, assay_cations, aptamer_chemistry, aptamer_modifications, source_pmid, doi, verbatim_quote, source_db from v_kd where \"measurement_class\" = :p0 and \"sequence_status\" = :p1 and \"verification_level\" = :p2 order by kd_log10_molar limit 51", "params": {"p0": "intrinsic", "p1": "pending_manual_supp", "p2": "multi_agent_verified"}}, "facet_results": {"measurement_class": {"name": "measurement_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "intrinsic", "label": "intrinsic", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "selected": true}], "truncated": false}, "target_type": {"name": "target_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "protein", "label": "protein", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&target_type=protein", "selected": false}], "truncated": false}, "tier": {"name": "tier", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "Gold", "label": "Gold", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&tier=Gold", "selected": false}], "truncated": false}, "assay_method": {"name": "assay_method", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "fluorescence", "label": "fluorescence", "count": 16, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=fluorescence", "selected": false}, {"value": "SPR", "label": "SPR", "count": 4, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=SPR", "selected": false}, {"value": "MST", "label": "MST", "count": 3, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=MST", "selected": false}, {"value": "EMSA", "label": "EMSA", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=EMSA", "selected": false}, {"value": "ITC", "label": "ITC", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=ITC", "selected": false}, {"value": "DPV", "label": "DPV", "count": 1, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&assay_method=DPV", "selected": false}], "truncated": false}, "binding_constant_type": {"name": "binding_constant_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "Kd", "label": "Kd", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&binding_constant_type=Kd", "selected": false}], "truncated": false}, "verification_level": {"name": "verification_level", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "multi_agent_verified", "label": "multi_agent_verified", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp", "selected": true}], "truncated": false}, "sequence_status": {"name": "sequence_status", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified", "results": [{"value": "pending_manual_supp", "label": "pending_manual_supp", "count": 44, "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&verification_level=multi_agent_verified", "selected": true}], "truncated": false}}, "suggested_facets": [{"name": "target_name_canonical", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=target_name_canonical"}, {"name": "target_uniprot", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=target_uniprot"}, {"name": "assay_temperature_k", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=assay_temperature_k"}, {"name": "assay_ph", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=assay_ph"}, {"name": "assay_buffer", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=assay_buffer"}, {"name": "aptamer_chemistry", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=aptamer_chemistry"}, {"name": "aptamer_modifications", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=aptamer_modifications"}, {"name": "source_pmid", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=source_pmid"}, {"name": "doi", "toggle_url": "https://apt-scout.org/scout/v_kd.json?measurement_class=intrinsic&sequence_status=pending_manual_supp&verification_level=multi_agent_verified&_facet=doi"}], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 180.3104211576283, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}