{"database": "scout", "table": "v_kd", "is_view": true, "human_description_en": "where measurement_class = \"intrinsic\", tier = \"Gold\" and verification_level = \"multi_agent_verified\" sorted by kd_log10_molar", "rows": [[331, "MutS", "protein", "O15457", "2-06", "ACTTCTGCCCGCCTCCTTCCTGGTAAAGTCATTAATAGGTGTGGGGTGCCGGGCATTTCGGAGACGAGATAGGCGGACACT", "1.23e-10 M", -9.91, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "25668425", "10.1021/acs.analchem.5b00171", "The best fi t was obtained at K d = 123 pM and [T]0 = 213 pM", "step2c_acs_v1"], [363, "HBcAg", "protein", null, "A-9", "AGCAGCACAGAGGTCAGATGAGGCCTGGTGATCGTGCCCAGGCCATATGAGCAAGGAACCCCTATGCGTGCTACCGTGAA", "2.0000000000000003e-10 M", -9.699, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, null, null, null, "DNA", null, "32250595", "10.1021/acs.analchem.9b05740", "This aptamer showed strong binding to HBcAg ( K d : 0.2 nM)", "step2c_acs_v1"], [318, "VEGF165", "protein", "P15692", "3R02", "TGTGGGGGTGGACTGGGTGGGTACC", "3e-10 M", -9.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "23237717", "10.1021/ac303023d", "The K d value for 3R02 was 300 pM", "step2c_acs_v1"], [478, "FLRPp (O serotype)", "protein", null, "FMD_1", null, "3.46e-10 M", -9.461, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", null, null, null, null, "DNA", null, "42010751", "10.1021/acs.analchem.5c04748", "dissociation constants ( KD ) of 3.46 \u00d7 10 -10 M", "step2c_acs_v1"], [358, "HBeAg", "protein", null, "EAg3-Py", "TTTTTTTTGGGCGAAGACCGGGACGGGAGGAAAGAGATGTTTGGTTTT", "4.0000000000000007e-10 M", -9.398, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, 7.4, "1 \u00d7 BB (50 mM Tris-HCl (pH 7.4), 5 mM KCl, 50 mM NaCl, 7 mM MgCl2, and 0.05% Tween 20)", null, "DNA", "pyrrolo-dC", "32250595", "10.1021/acs.analchem.9b05740", "The K d value is 0.4 nM for the HBeAg complex with the pyrrolo-dC modi fi ed aptamer EAg3", "step2c_acs_v1"], [415, "BDNF", "protein", "P23560", "NV_B12", "GGATTTGAGCTTATGTGGCATAGGTTGCCTGGGTGGGTGGGGTCGGGGAA", "5e-10 M", -9.301, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "ALISA", null, null, "1 \u00d7 selection buffer", null, "DNA", "biotin", "38149631", "10.1021/acschemneuro.3c00661", "The equilibrium dissociation constant ( K d) for the NV_B12/BDNF interaction was obtained by fitting the equation, Y = B max \u00d7 X /( K d + X )... The K d value determined to be 0.5 nM (95% CI: 0.4 -0.6 nM)", "step2c_acs_v1"], [343, "PlanarAu", "protein", null, "1N", "TATGCATGTGTAGTAAGACCTAGTCCACAATCAACG", "5.600000000000001e-10 M", -9.252, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, "AIB", null, "DNA", null, "30189130", "10.1021/acscombsci.8b00048", "aptamer 1N showing the highest affinity (0.56 nM)", "step2c_acs_v1"], [332, "MutS", "protein", "O15457", "2-06", "ACTTCTGCCCGCCTCCTTCCTGGTAAAGTCATTAATAGGTGTGGGGTGCCGGGCATTTCGGAGACGAGATAGGCGGACACT", "6.5e-10 M", -9.187, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "25668425", "10.1021/acs.analchem.5b00171", "The experimental points from the second step resulted in the best fi t with the theoretical dependence of R versus [L] 0 at K d = 650 pM", "step2c_acs_v1"], [459, "PSMA", "protein", "Q04609", "C3", null, "8.000000000000001e-10 M", -9.097, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "EMSA", null, null, "5 mM Mg2+", null, "DNA", "phenol-dT; naphthyl-dC; PSMA-617 bait", "41126016", "10.1021/jacs.5c13307", "an exemplar shows very high affinity for PSMA ( K d \u223c 0.8 nM).", "step2c_acs_v1"], [398, "neomycin", "protein", "Q96LI5", "Aptamer A", "GGACUGGGCGAGAAGUUUAGUCC", "1e-09 M", -9.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "36453647", "10.1021/acschembio.2c00653", "The binding affinity of neomycin to Aptamer A shows a strong K d  of 1 nM with an enthalpy and entropy value of -100 kJ/mol & -163.1 J/mol. K", "step2c_acs_v1"], [432, "Sc3+", "protein", "Q96PL5", "Sc-1", "CTCTCGACGACGGACCATTCCCGTGGAATGACTACGTATATGTCGTC", "1e-09 M", -9.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "fluorescence", null, null, "SELEX buffer", null, "DNA", null, "39743479", "10.1021/jacs.4c13768", "true K d for the binding of Sc-1 to Sc 3+ to be 1.0 nM", "step2c_acs_v1"], [458, "PSMA", "protein", "Q04609", "C3 (without fluorescein)", null, "1e-09 M", -9.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "EMSA", null, null, null, null, "DNA", "phenol-dT; naphthyl-dC; Cy5 label", "41126016", "10.1021/jacs.5c13307", "EMSA data show that Cy5-labeled C3 without fluorescein binds PSMA just as strongly as the parent construct, with an apparent K d of \u223c 1 nM (Figure S9).", "step2c_acs_v1"], [372, "beta-conglutin", "protein", null, "11-mer", "GGTGGGGGTGG", "1.05e-09 M", -8.979, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "MST", 298.15, null, "binding buffer with 0.05% v/v Tween-20", null, "DNA", null, "33498970", "10.3390/ijms22031150", "KD values determined (Figure 6b) are very similar (11-mer: 1.05 nM", "step2c_acs_v1"], [340, "AP65", "protein", "Q13882", "AP65_A1", "AGCTCCAGAAGATAAATTACAGGTGAGGGCGGGCGGGTGGTTGTAATATGATCGAATGGTATATGTGTGTTTGCAACTAGGATACTATGACCCCG", "1.057e-09 M", -8.976, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "ELAA", 298.15, 6.4, "binding buffer (10 mM phosphate, 138 mM NaCl, 2.7 mM KCl, 1.5 mM MgCl2 at pH 6.4)", null, "DNA", "5'-biotinylated", "29972299", "10.1021/acsinfecdis.8b00065", "A K D value of 1.057 nM was obtained using the sigmoidal dose-response curve model", "step2c_acs_v1"], [356, "HBeAg", "protein", null, "A-9S", "ACTTTTTTGGTCAGATGAGGCCTGGTGATCGTGCCCAGGCCATATGAGCAAGGAACCCCTATGCGTGCT", "1.2e-09 M", -8.921, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, 7.4, "1 \u00d7 BB (50 mM Tris-HCl (pH 7.4), 5 mM KCl, 50 mM NaCl, 7 mM MgCl2, and 0.05% Tween 20)", null, "DNA", "/5AmMC6/", "32250595", "10.1021/acs.analchem.9b05740", "The measured dissociation constant ( K d) is improved by 19 times \ue0d5 from a K d value of 22.9 nM with the 80-nt sequence to a K d of 1.2 nM with the new 61-nt aptamer.", "step2c_acs_v1"], [433, "PvTRAg", "protein", null, "Apt_16", "TTAATAACATGAGTTATTGAATTATTGTTTATTTTTTTTTTTTTG", "1.2e-09 M", -8.921, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, "DNA", null, "40042916", "10.1021/acsinfecdis.4c01047", "The K D of Apt_14 and Apt_16 was found to be comparable, 1.9 and 1.2 nM, respectively", "step2c_acs_v1"], [328, "ATP", "protein", "P00846", "Huizenga-Szostak ATP aptamer", null, "1.3e-09 M", -8.886, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_supp_oa", null, null, "fluorescence", null, null, null, null, "DNA", null, "25170558", "10.1021/bc500286r", "binding a ffi nity can be tuned over 4 orders of magnitude (1.3 nM -203 \u03bc M)", "step2c_acs_v1"], [394, "IgE", "protein", "P0DOX4", "S2", "GACTACCCGGGTATCTAATCCGACCATTTTTCGTCTCCTTTGTACGAGCAGTGTGCTCGACCTGCCGCCCGTAGG", "1.5500000000000002e-09 M", -8.81, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "NECEEM", null, 9.0, "10 mM Tris-HCl buffer (pH 9.0)", null, "DNA", "FITC", "36144553", "10.3390/molecules27185818", "Based on the results of these experiments, the K D values of S1 and S2 were estimated to be 0.83 and 1.55 nM, respectively", "step2c_acs_v1"], [337, "human \u03b1-thrombin", "protein", "P00734", "LOOPER modified thrombin aptamer", null, "1.6000000000000003e-09 M", -8.796, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "SPR", null, null, null, null, "DNA", "diversely functionalized; heteromultivalent", "28938065", "10.1021/jacs.7b07241", "Using single-cycle kinetics surface plasmon resonance (SPR), the LOOPER aptamer exhibited a Kd of 1.6 nM", "step2c_acs_v1"], [359, "HBeAg", "protein", null, "EAg3", "TTTTTTTTGGGCGAAGACCGGGACGGGAGGAAAGAGATGTTTGGTTTT", "1.7000000000000001e-09 M", -8.77, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, 7.4, "1 \u00d7 BB (50 mM Tris-HCl (pH 7.4), 5 mM KCl, 50 mM NaCl, 7 mM MgCl2, and 0.05% Tween 20)", null, "DNA", null, "32250595", "10.1021/acs.analchem.9b05740", "The K d value is 0.4 nM for the HBeAg complex with the pyrrolo-dC modi fi ed aptamer EAg3, as compared to the K d value of 1.7 nM with the unmodi fi ed EAg3 aptamer.", "step2c_acs_v1"], [374, "beta-conglutin", "protein", null, "TT-11-mer", "TTGGTGGGGGTGG", "1.88e-09 M", -8.726, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "MST", 298.15, null, "binding buffer with 0.05% v/v Tween-20", null, "DNA", null, "33498970", "10.3390/ijms22031150", "KD values determined (Figure 6b) are very similar (... TT-11 mer: 1.88 nM", "step2c_acs_v1"], [316, "CD44-HABD", "protein", null, "Motif 4 (ADDA adduct)", null, "2e-09 M", -8.699, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23057694", "10.1021/bi300471d", "motifs 2 and 4(ADDA adduct) have ~2 nM affinity to CD44-HABD", "step2c_acs_v1"], [376, "beta-conglutin", "protein", null, "11-mer-TT", "GGTGGGGGTGGTT", "2.59e-09 M", -8.587, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "MST", 298.15, null, "binding buffer with 0.05% v/v Tween-20", null, "DNA", null, "33498970", "10.3390/ijms22031150", "KD values determined (Figure 6b) are very similar (... and 11-mer-TT: 2.59 nM)", "step2c_acs_v1"], [375, "beta-conglutin", "protein", null, "TT-11-mer-TT", "TTGGTGGGGGTGGTT", "2.71e-09 M", -8.567, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "MST", 298.15, null, "binding buffer with 0.05% v/v Tween-20", null, "DNA", null, "33498970", "10.3390/ijms22031150", "KD values determined (Figure 6b) are very similar (... TT-11-mer-TT: 2.71 nM", "step2c_acs_v1"], [322, "S-adenosylmethionine", "protein", "P17707", "Bs SAM-I riboswitch", null, "3.0000000000000004e-09 M", -8.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23343213", "10.1021/ja310742m", "Both \u03bc MSA values agree well with results from the in-line probing assays performed using identical buffer conditions: ... 3 nM K d , respectively", "step2c_acs_v1"], [323, "S-adenosylmethionine", "protein", "P17707", "Pi SAM-I riboswitch", null, "3.0000000000000004e-09 M", -8.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "23343213", "10.1021/ja310742m", "which is on the order of the 3 nM value measured using a conventional inline probing assay", "step2c_acs_v1"], [378, "dT70", "protein", null, "DCC-SSB", null, "3.0000000000000004e-09 M", -8.523, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_figure", null, null, null, null, null, null, null, null, null, "34085169", "10.1007/s12010-021-03585-x", "At a low concentration ( \u223c 2.5 nM), the titration with dT70 gave an approximate assessment of affinity ( K d \u223c 3 nM).", "step2c_acs_v1"], [367, "SARS-CoV-2 RBD", "protein", null, "CoV2-RBD-1", "CAGCACCGACCTTGTGCTTTGGGAGTGCTGGTCCAAGGGCGTTAATGGACA", "3.1000000000000005e-09 M", -8.509, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "backfill_text_verified", null, "flow_cytometry", null, null, "PBS with 0.55 mM MgCl2", null, "DNA", null, "32551560", "10.1021/acs.analchem.0c01394", "the dissociation constant values ( K d) of the CoV2-RBD-1 aptamer ... were 3.1 nM", "step2c_acs_v1"], [338, "human \u03b1-thrombin", "protein", "P00734", "LOOPER modified thrombin aptamer", null, "4e-09 M", -8.398, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "28938065", "10.1021/jacs.7b07241", "Preliminary binding analysis by label-free microscale thermophoresis showed a promising dissociation constant K d = 4 nM for thrombin", "step2c_acs_v1"], [410, "melamine", "protein", null, "Apt M", "TTCCTTTTCTCTCC", "4.4000000000000005e-09 M", -8.357, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "backfill_text_verified", null, null, null, null, null, null, "DNA", "abasic site", "37343019", "10.1021/acs.analchem.2c05777", "dissociation constant K d = 4.4 nM", "step2c_acs_v1"], [320, "VEGF165", "protein", "P15692", "VEap121", "TGTGGGGGTGGACGGGCCGGGTAGA", "4.700000000000001e-09 M", -8.328, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "SPR", 293.15, 7.4, "Tris-buffered saline (TBS: 10 mM Tris-HCl, 100 mM NaCl, 5 mM KCl, pH 7.4)", null, "DNA", null, "23237717", "10.1021/ac303023d", "As the calculated K d value of VEap121 was 4.7 nM", "step2c_acs_v1"], [327, "Myoglobin", "protein", "P02144", "Myo40-7-27", "CCCTCCTTTCCTTCGACTAGATCTGCTGCGTTGTTCCGA", "4.93e-09 M", -8.307, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, "DNA", null, "24914856", "10.1021/ac501088q", "The aptamer with the highest a ffi nity ( K d = 4.93 nM) was then used for the fabrication of a label-free supersandwich electrochemical biosensor for Myo detection", "step2c_acs_v1"], [455, "biliverdin", "protein", "P53004", "Bvd4", "GACGACGGGTGTGGAACAGTGCGAATACTTTCGAGTCGTC", "6.000000000000001e-09 M", -8.222, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "40669049", "10.1021/acschembio.5c00438", "For the biliverdin selection, the tightest affinity aptamer has a dissociation costant ( K d ) value of 6 nM determined using isothermal titration calorimetry (ITC)", "step2c_acs_v1"], [461, "Lipopolysaccharide from Klebsiella pneumoniae ATCC 15380", "protein", null, "aptamer seq. 5", null, "6.68e-09 M", -8.175, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "DPV", null, null, "1 \u00d7 PBS", null, "DNA", "biotin", "41323700", "10.1039/d5ra06759f", "The binding affinity of aptamer seq. 5 was 6.68 nM (Fig. 9C).", "step2c_acs_v1"], [445, "Cu2+", "protein", "Q6UVY6", "Co-1", "GACGACGGAACGGAGGTTCTTAGGTCGGTAGACCGAGTCGTC", "8e-09 M", -8.097, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, null, null, null, null, null, null, null, "40656531", "10.1039/d5sc02436f", "The corresponding true K d values were ... 8 nM for Cu 2+", "step2c_acs_v1"], [348, "NP", "protein", "Q16612", "NP-C04", null, "8.1e-09 M", -8.092, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "fluorescence", null, 7.4, "20 mM HEPES, 150 mM NaCl, 2 mM KCl, 2 mM MgCl2, and 2 mM CaCl2 (pH 7.4)", null, "DNA", "FAM", "30740973", "10.1021/acs.analchem.8b04623", "the K d values of NP-D01, NP-C04, and NP-D02 were 76..1 \u00b1 10.9, 8.1 \u00b1 2.4, and 41.3 \u00b1 9.5 nM, respectively.", "step2c_acs_v1"], [423, "TAR RNA", "protein", "Q13395", "TAR RNA aptamer (best binding)", null, "9.000000000000001e-09 M", -8.046, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "39167715", "10.1021/jacs.4c08824", "A Biolayer Interferometry (BLI) experiment revealed that TAR RNA aptamers with the best binding affinity exhibited the dissociation constant ( K D) at 9 nM", "step2c_acs_v1"], [362, "HBeAg", "protein", null, "EAg2", "TTTTTTTTGGGCGAAGACCGGGACGGGAGGAAAGTGTAGATTGGAAAA", "9.2e-09 M", -8.036, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, 7.4, "1 \u00d7 BB (50 mM Tris-HCl (pH 7.4), 5 mM KCl, 50 mM NaCl, 7 mM MgCl2, and 0.05% Tween 20)", null, "DNA", null, "32250595", "10.1021/acs.analchem.9b05740", "A comparison of the binding of HBeAg with the four aptamers (Figure S3) shows K d values of 44.2 nM for EAg0, 9.5 nM for EAg1, 9.2 nM for EAg2", "step2c_acs_v1"], [361, "HBeAg", "protein", null, "EAg1", "TTTTTTTTGGGCGAAGACCGGGACGGGAGGAAAGTGTAGATTGGTTTT", "9.5e-09 M", -8.022, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "affinity_real_time_qPCR", null, 7.4, "1 \u00d7 BB (50 mM Tris-HCl (pH 7.4), 5 mM KCl, 50 mM NaCl, 7 mM MgCl2, and 0.05% Tween 20)", null, "DNA", null, "32250595", "10.1021/acs.analchem.9b05740", "A comparison of the binding of HBeAg with the four aptamers (Figure S3) shows K d values of 44.2 nM for EAg0, 9.5 nM for EAg1", "step2c_acs_v1"], [345, "streptavidin", "protein", null, "S8", null, "1e-08 M", -8.0, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "30520292", "10.1021/acssensors.8b00945", "At pH 7.4, we determined that S8 has a K d of 10 nM", "step2c_acs_v1"], [366, "trastuzumab", "protein", "Q9ULR3", "CH1S-3", null, "1.0300000000000001e-08 M", -7.987, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, "MST", 298.15, null, "washing bu ff er with the addition of 0.005% Tween 20", null, "DNA", "5'-Cy5", "32516525", "10.1021/jacs.9b13370", "a ffi nity with a K d value of aptamer CH1S-3 of 10.3 nM", "step2c_acs_v1"], [431, "Sc3+", "protein", "Q96PL5", "Sc-1", "CTCTCGACGACGGACCATTCCCGTGGAATGACTACGTATATGTCGTC", "1.0300000000000001e-08 M", -7.987, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "fluorescence", null, null, "SELEX buffer", null, "DNA", null, "39743479", "10.1021/jacs.4c13768", "an apparent K d value of 10.3 nM was obtained", "step2c_acs_v1"], [334, "17 \u03b2 -Estradiol", "protein", "P42167", "22-mer aptamer", null, "1.1000000000000001e-08 M", -7.959, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_manual_supp", null, null, null, null, null, null, null, null, null, "25803717", "10.1021/acs.analchem.5b00335", "new 35-mer and 22-mer aptamers were generated with K D ' s of 14 and 11 nM", "step2c_acs_v1"], [344, "PlanarAu", "protein", null, "1N truncated", "TATGCATGTGTATATCAACACTCCGGGTCTAATCGTTCA", "1.304e-08 M", -7.885, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "original", null, "QCM", null, null, "AIB", null, "DNA", null, "30189130", "10.1021/acscombsci.8b00048", "1N truncated (Kd = 13.04 nM)", "step2c_acs_v1"], [368, "SARS-CoV-2 RBD", "protein", null, "CoV2-RBD-4", "ATCCAGAGTGACGCAGCATTTCATCGGGTCCAAAAGGGGCTGCTCGGGATTGCGGATATGGACACGT", "1.3600000000000001e-08 M", -7.866, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "verified_in_text_or_SI", "backfill_text_verified", null, "flow_cytometry", null, null, "PBS with 0.55 mM MgCl2", null, "DNA", null, "32551560", "10.1021/acs.analchem.0c01394", "the dissociation constant values ( K d) of the ... 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