{"database": "scout", "table": "v_kd", "is_view": true, "human_description_en": "where sequence_status = \"pending_supp_oa\" sorted by kd_log10_molar", "rows": [[247, "Human thrombin", "protein", "P00734", "Lin08-08", null, "0.4 nM", -9.398, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, "KEEP_seq_in_figure", "SPR", null, 7.4, "PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20", null, "DNA", null, "37621412", "10.1016/j.omtn.2023.07.038", "Lin(08-08) | 1.63 10^6 | 6.94 10^-4 | 0.4", "step2c_literal_v3"], [249, "Human thrombin", "protein", "P00734", "Pse08-08", null, "0.4 nM", -9.398, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, "KEEP_seq_in_figure", "SPR", null, 7.4, "PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20", null, "DNA", null, "37621412", "10.1016/j.omtn.2023.07.038", "Pse(08-08) | 1.19 10^6 | 5.10 10^-4 | 0.4", "step2c_literal_v3"], [724, "Heparin-binding protein", "protein", "P21246", "Apt-13", null, "1.04 nM", -8.983, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "38675537", "10.3390/molecules29081717", "The KD values of the three aptamers were 3.42, 1.44, and 1.04 nM, respectively", "elsevier_step2c"], [328, "ATP", "protein", "P00846", "Huizenga-Szostak ATP aptamer", null, "1.3e-09 M", -8.886, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_supp_oa", null, null, "fluorescence", null, null, null, null, "DNA", null, "25170558", "10.1021/bc500286r", "binding a ffi nity can be tuned over 4 orders of magnitude (1.3 nM -203 \u03bc M)", "step2c_acs_v1"], [723, "Heparin-binding protein", "protein", "P21246", "Apt-02", null, "1.44 nM", -8.842, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "38675537", "10.3390/molecules29081717", "The KD values of the three aptamers were 3.42, 1.44, and 1.04 nM, respectively", "elsevier_step2c"], [202, "CD8a", "protein", "P01732", "A3", null, "1.9 nM", -8.721, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers have apparent K D values of 18.3 \u00b1 4.6, 1.9 \u00b1 0.8 and 2.4 \u00b1 0.9  nM, respectively", "step2c_literal_v3"], [203, "CD8a", "protein", "P01732", "A8", null, "2.4 nM", -8.62, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers have apparent K D values of 18.3 \u00b1 4.6, 1.9 \u00b1 0.8 and 2.4 \u00b1 0.9  nM, respectively", "step2c_literal_v3"], [226, "transferrin receptor 1", "protein", "P02786", "JBA8.26", null, "3.3 nM", -8.481, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "35875870", "10.1021/jacs.2c05349", "JBA8.26 bound TfR1 hi H9 T-lymphoma cells with an apparent K D of 3.3 \u00b1 0.6 nM", "step2c_literal_v3"], [250, "Mouse thrombin", "protein", null, "Pse08-08", null, "4.2 nM", -8.377, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, "KEEP_seq_in_figure", "SPR", null, 7.4, "PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20", null, "DNA", null, "37621412", "10.1016/j.omtn.2023.07.038", "Pse(08-08) | 7.35 10^5 | 3.06 10^-3 | 4.2", "step2c_literal_v3"], [224, "transferrin receptor 1", "protein", "P02786", "JBA8.1", null, "5.5 nM", -8.26, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", "fluorescein-labeled", "35875870", "10.1021/jacs.2c05349", "JBA8.1 has an apparent binding affinity (K D ) of 5.5 \u00b1 1.2 nM", "step2c_literal_v3"], [63, "CD8a", "protein", "P01732", "A8", null, "5.59 nM", -8.253, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [248, "Mouse thrombin", "protein", null, "Lin08-08", null, "6.7 nM", -8.174, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, "KEEP_seq_in_figure", "SPR", null, 7.4, "PBS [pH 7.4], 0.05 [v/v%] surfactant Tween 20", null, "DNA", null, "37621412", "10.1016/j.omtn.2023.07.038", "Lin(08-08) | 6.41 10^5 | 4.30 10^-3 | 6.7", "step2c_literal_v3"], [87, "transferrin receptor 1", "protein", "P02786", "JBA8.26", null, "6.87 nM", -8.163, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", null, null, null, null, "DNA", null, "35875870", "10.1021/jacs.2c05349", "Using BLI, JBA8.26 was found to bind immobilized TfR1 with a K D of 6.87 \u00b1 0.04 nM", "step2c_literal_v3"], [689, "EN2", "protein", "P19622", "EBA", null, "8.26 nM", -8.083, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35798816", "10.1038/s41598-022-15556-1", "EBA had K d =  8.26 nM (R 2 =  0.971)", "elsevier_step2c"], [225, "transferrin receptor 1", "protein", "P02786", "tJBA8.1", null, "10.9 nM", -7.963, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "35875870", "10.1021/jacs.2c05349", "versus that of 10.9 \u00b1 2.4 nM for tJBA8.1", "step2c_literal_v3"], [697, "\u03b2-conglutin", "protein", null, "unmodified \u03b2-CBA II aptamer", null, "11.1 nM", -7.955, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "36354481", "10.3390/bios12110972", "with a similar KD of 11.1 nM and 18.5 nM obtained for the unmodified and modified aptamer, respectively.", "elsevier_step2c"], [62, "CD8a", "protein", "P01732", "A3", null, "14.7 nM", -7.833, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [201, "CD8a", "protein", "P01732", "A1", null, "18.3 nM", -7.738, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers have apparent K D values of 18.3 \u00b1 4.6, 1.9 \u00b1 0.8 and 2.4 \u00b1 0.9  nM, respectively", "step2c_literal_v3"], [698, "\u03b2-conglutin", "protein", null, "biotinylated dUTPs aptamer", null, "18.5 nM", -7.733, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "36354481", "10.3390/bios12110972", "with a similar KD of 11.1 nM and 18.5 nM obtained for the unmodified and modified aptamer, respectively.", "elsevier_step2c"], [61, "CD8a", "protein", "P01732", "A1", null, "20.1 nM", -7.697, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, "binding buffer with 0.01% Tween 20", null, "DNA", null, "31209354", "10.1038/s41551-019-0411-6", "the A1, A3 and A8 aptamers bound the protein with binding affinities ( K D values) of 20.1 \u00b1 0.2,  14.7 \u00b1 0.1  and  5.59 \u00b1 0.11  nM, respectively", "step2c_literal_v3"], [677, "saxitoxin", "protein", "O60939", "45e", null, "21.2 nM", -7.674, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35324725", "10.3390/toxins14030228", "aptamer 45e with a K d value of 21.2 nM", "elsevier_step2c"], [128, "CD117", "protein", "P10721", "Apta02", null, "21.8 nM", -7.662, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 \u00b5 m, respectively ( Figure 2 a,b).", "step2c_literal_v3"], [302, "prostate-cancer-derived small extracellular vesicles", "cell/EV", "Q99523", "seq25", null, "24.02 nM", -7.619, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "SPR", null, null, "PBST buffer", null, "DNA", "5'-FAM", "41646885", "10.1016/j.omtn.2026.102836", "The affinity of seq25 for positive selection was significantly higher than that of the other aptamers, with a KD of 24.02 nM", "step2c_literal_v3"], [86, "transferrin receptor 1", "protein", "P02786", "tJBA8.1", null, "25.11 nM", -7.6, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", null, null, null, null, "DNA", "biotinylated", "35875870", "10.1021/jacs.2c05349", "tJBA8.1 bound the TfR1 protein with a K D value of 25.11 \u00b1 0.19 nM", "step2c_literal_v3"], [227, "transferrin receptor 1", "protein", "P02786", "tJBA8.1", null, "25.6 nM", -7.592, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", null, null, null, null, "DNA", null, "35875870", "10.1021/jacs.2c05349", "compared to tJBA8.1's apparent K D of 25.6 \u00b1 13.0 nM for these cells", "step2c_literal_v3"], [716, "Enrofloxacin", "protein", "P05177", "ENR-Apt 6", null, "35.08 nM", -7.455, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "38540931", "10.3390/foods13060941", "Figure 4A shows the non-linear fitting curve of ENR-Apt 6, with a Kd value of 35.08 nM.", "elsevier_step2c"], [222, "CD20", "protein", "P11836", "WB1-CD20", null, "73.0 nM", -7.137, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 298.15, null, "Cell Suspension Buffer (CSB)", null, "DNA", "5'-FAM", "35829681", "10.1021/acs.biochem.2c00105", "The apparent affinities of WB1-CD20 and WB2-CD20 were calculated as 73 nM and 163 nM at 25\u00b0C, respectively", "step2c_literal_v3"], [97, "N-acetylneuraminic acid", "protein", "Q8NFW8", "Neu5Ac aptamer", null, "91.0 nM", -7.041, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "ITC", 310.15, 7.4, "1\u00d7 aptamer binding buffer (50 mM Tris-HCl, 5 mM KCl, 100 mM NaCl and 1 mM MgCl2, pH 7.4)", "1.0", "DNA", null, "37217750", "10.1038/s41587-023-01801-z", "To validate ARPLA, we first determined the binding affinity ( K d ) of the Neu5Ac aptamer by isothermal titration calorimetry (ITC) as 91 nM (Extended Data Fig. 2a,b)", "step2c_literal_v3"], [687, "mouse IL-2", "protein", null, "M20", null, "91.0 nM", -7.041, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35756119", "10.1016/j.heliyon.2022.e09721", "The results indicated that the af fi nity of the M20 aptamer was greater than the M15, and its predicted Kd was 91 nM", "elsevier_step2c"], [678, "saxitoxin", "protein", "O60939", "75a", null, "136.0 nM", -6.866, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35324725", "10.3390/toxins14030228", "aptamer 75a with a K d value of 136 nM", "elsevier_step2c"], [220, "CD19", "protein", "P15391", "WB15-CD19", null, "153.0 nM", -6.815, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 298.15, null, "Cell Suspension Buffer (CSB)", null, "DNA", "5'-FAM", "35829681", "10.1021/acs.biochem.2c00105", "At 25 \u00b0C, WB15-CD19 showed an apparent affinity of 153 nM", "step2c_literal_v3"], [223, "CD20", "protein", "P11836", "WB2-CD20", null, "163.0 nM", -6.788, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 298.15, null, "Cell Suspension Buffer (CSB)", null, "DNA", "5'-FAM", "35829681", "10.1021/acs.biochem.2c00105", "The apparent affinities of WB1-CD20 and WB2-CD20 were calculated as 73 nM and 163 nM at 25\u00b0C, respectively", "step2c_literal_v3"], [221, "CD19", "protein", "P15391", "WB17-CD19", null, "187.0 nM", -6.728, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 298.15, null, "Cell Suspension Buffer (CSB)", null, "DNA", "5'-FAM", "35829681", "10.1021/acs.biochem.2c00105", "and WB17-CD19 showed an apparent affinity of 187 nM (Figure S12A-B).", "step2c_literal_v3"], [419, "cortisol", "protein", "P08185", "CSS.3", null, "2.4000000000000003e-07 M", -6.62, "intrinsic", "Kd", "Gold", "v4", "multi_agent_verified", "pending_supp_oa", null, null, null, null, null, null, null, null, null, "38270529", "10.1021/acssensors.3c02004", "Our own internal work confirmed that CSS.3 had the best binding affinity in binding buffer with a K D of 240 nM", "step2c_acs_v1"], [673, "kanamycin", "protein", null, "Apt 1/Apt 2 (split aptamers)", null, "247.0 nM", -6.607, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35316405", "10.1007/s00604-022-05235-3", "With the (GlcN)5 added in the binding buffer, the Kd was measured to be 247 nM", "elsevier_step2c"], [672, "kanamycin", "protein", null, "Apt 1/Apt 2 (split aptamers)", null, "304.0 nM", -6.517, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35316405", "10.1007/s00604-022-05235-3", "The split aptamers exhibited high affinity towards the kanamycin, with an Kd of 304 nM.", "elsevier_step2c"], [263, "H-6 cells", "cell/EV", "O14756", "Apta25", null, "0.42 \u00b5M", -6.377, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "H-6 cells showed binding with Apta25 ( K D value-0.42 \u00b1 0.093 \u00b5 m)", "step2c_literal_v3"], [688, "mouse IL-2", "protein", null, "M15", null, "600.0 nM", -6.222, "intrinsic", "Kd", "Gold", "elsevier", "extraction_verified", "pending_supp_oa", null, null, null, null, null, "text", null, null, null, "35756119", "10.1016/j.heliyon.2022.e09721", "The calculation of the dissociation constant predicted 91 and 600 nM Kd for M20 and M15, respectively", "elsevier_step2c"], [261, "K-1 cells", "cell/EV", "O60814", "Apta30", null, "0.66 \u00b5M", -6.18, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta30 ( K D -0.66 \u00b1 0.12 \u00b5 m)", "step2c_literal_v3"], [129, "CD117", "protein", "P10721", "Apta04", null, "1100.0 nM", -5.959, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta02 and Apta04 exhibited K D 's of 21.8 nm and 1.10 \u00b5 m, respectively ( Figure 2 a,b).", "step2c_literal_v3"], [264, "H-6 cells", "cell/EV", "O14756", "Apta30", null, "1.107 \u00b5M", -5.956, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "H-6 cells showed binding with ... Apta30 ( K D -1.107 \u00b1 0.208 \u00b5 m)", "step2c_literal_v3"], [131, "CD123", "protein", "O75794", "Apta25", null, "1.16 \u00b5M", -5.936, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 \u00b5 m for ZW25 and 15.6 \u00b5 m for CY30 (Figure S2, Supporting Information).", "step2c_literal_v3"], [262, "K-1 cells", "cell/EV", "O60814", "Apta25", null, "1.358 \u00b5M", -5.867, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta25 ( K D value-1.358 \u00b1 0.201 \u00b5 m)", "step2c_literal_v3"], [259, "K-1 cells", "cell/EV", "O60814", "Apta02", null, "1.821 \u00b5M", -5.74, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta02 ( K D value-1.821 \u00b1 0.117 \u00b5 m)", "step2c_literal_v3"], [260, "K-1 cells", "cell/EV", "O60814", "Apta04", null, "1.867 \u00b5M", -5.729, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "Apta04 ( K D value-1.867 \u00b1 0.19 \u00b5 m)", "step2c_literal_v3"], [121, "CTNNA1", "protein", "P35221", "EA2", null, "2.07 \u00b5M", -5.684, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "MST", null, null, null, null, "DNA", "biotinylated", "40265971", "10.1002/advs.202411930", "The K d values (2.07 \u00b1 0.60 \u00b5 M) obtained from MST assay (Figure 2l) further corroborated the specific binding between CTNNA1 and EA2.", "step2c_literal_v3"], [265, "H-9 cells", "cell/EV", "Q8IVB4", "Apta02", null, "4.93 \u00b5M", -5.307, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "H-9 cells showed binding with Apta02 ( K D value-4.93 \u00b1 0.367 \u00b5 m)", "step2c_literal_v3"], [266, "H-9 cells", "cell/EV", "Q8IVB4", "Apta04", null, "5.402 \u00b5M", -5.267, "non_intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "flow_cytometry", 310.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "H-9 cells showed binding with ... Apta04 ( K D value-5.402 \u00b1 0.795 \u00b5 m)", "step2c_literal_v3"], [130, "CD123", "protein", "O75794", "Apta30", null, "15.6 \u00b5M", -4.807, "intrinsic", "Kd", "Gold", "v4", "extraction_verified", "pending_supp_oa", null, null, "BLI", 298.15, null, null, null, "DNA", null, "40487293", "10.1002/adfm.202425394", "BLI binding assays of both aptamers demonstrated binding to human recombinant CD123 with K D s of 1.16 \u00b5 m for ZW25 and 15.6 \u00b5 m for CY30 (Figure S2, Supporting Information).", "step2c_literal_v3"]], "truncated": false, "filtered_table_rows_count": 49, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "target_name_canonical", "target_type", "target_uniprot", "aptamer_name", "aptamer_seq", "kd_reported", "kd_log10_molar", "measurement_class", "binding_constant_type", "tier", "source_origin", "verification_level", "sequence_status", "seq_source", "pi_provenance_flag", "assay_method", "assay_temperature_k", "assay_ph", "assay_buffer", "assay_cations", "aptamer_chemistry", "aptamer_modifications", "source_pmid", "doi", "verbatim_quote", "source_db"], "primary_keys": [], "units": {}, "query": {"sql": "select id, target_name_canonical, target_type, target_uniprot, aptamer_name, aptamer_seq, kd_reported, kd_log10_molar, measurement_class, binding_constant_type, tier, source_origin, verification_level, sequence_status, seq_source, pi_provenance_flag, assay_method, assay_temperature_k, assay_ph, assay_buffer, assay_cations, aptamer_chemistry, aptamer_modifications, source_pmid, doi, verbatim_quote, source_db from v_kd where \"sequence_status\" = :p0 order by kd_log10_molar limit 51", "params": {"p0": "pending_supp_oa"}}, "facet_results": {"measurement_class": {"name": "measurement_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "intrinsic", "label": "intrinsic", "count": 25, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&measurement_class=intrinsic", "selected": false}, {"value": "non_intrinsic", "label": "non_intrinsic", "count": 24, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&measurement_class=non_intrinsic", "selected": false}], "truncated": false}, "target_type": {"name": "target_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "protein", "label": "protein", "count": 40, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&target_type=protein", "selected": false}, {"value": "cell/EV", "label": "cell/EV", "count": 9, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&target_type=cell%2FEV", "selected": false}], "truncated": false}, "tier": {"name": "tier", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "Gold", "label": "Gold", "count": 49, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&tier=Gold", "selected": false}], "truncated": false}, "assay_method": {"name": "assay_method", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "flow_cytometry", "label": "flow_cytometry", "count": 19, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=flow_cytometry", "selected": false}, {"value": "BLI", "label": "BLI", "count": 9, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=BLI", "selected": false}, {"value": "SPR", "label": "SPR", "count": 5, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=SPR", "selected": false}, {"value": "ITC", "label": "ITC", "count": 1, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=ITC", "selected": false}, {"value": "MST", "label": "MST", "count": 1, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=MST", "selected": false}, {"value": "fluorescence", "label": "fluorescence", "count": 1, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&assay_method=fluorescence", "selected": false}], "truncated": false}, "binding_constant_type": {"name": "binding_constant_type", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "Kd", "label": "Kd", "count": 49, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&binding_constant_type=Kd", "selected": false}], "truncated": false}, "verification_level": {"name": "verification_level", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "extraction_verified", "label": "extraction_verified", "count": 47, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&verification_level=extraction_verified", "selected": false}, {"value": "multi_agent_verified", "label": "multi_agent_verified", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&verification_level=multi_agent_verified", "selected": false}], "truncated": false}, "sequence_status": {"name": "sequence_status", "type": "column", "hideable": false, "toggle_url": "/scout/v_kd.json?sequence_status=pending_supp_oa", "results": [{"value": "pending_supp_oa", "label": "pending_supp_oa", "count": 49, "toggle_url": "https://apt-scout.org/scout/v_kd.json", "selected": true}], "truncated": false}}, "suggested_facets": [{"name": "target_name_canonical", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=target_name_canonical"}, {"name": "target_uniprot", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=target_uniprot"}, {"name": "source_origin", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=source_origin"}, {"name": "assay_temperature_k", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=assay_temperature_k"}, {"name": "assay_buffer", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=assay_buffer"}, {"name": "aptamer_modifications", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=aptamer_modifications"}, {"name": "source_pmid", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=source_pmid"}, {"name": "doi", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=doi"}, {"name": "source_db", "toggle_url": "https://apt-scout.org/scout/v_kd.json?sequence_status=pending_supp_oa&_facet=source_db"}], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 62.99388501793146, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}