id,gene_symbol,protein_name,surface_class,surface_evidence,ev_map_hallmark,in_cev_map,in_vesiclepedia,in_exocarta,pdb_count,top_disease,disease_score,drug_count_approved,targetability_score
P25054,APC,Adenomatous polyposis coli protein,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,31,familial adenomatous polyposis 1,0.8462165290909345,,0.654
Q9Y4U1,MMACHC,Cyanocobalamin reductase / alkylcobalamin dealkylase,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,7,"Methylmalonic acidemia with homocystinuria, type cblC",0.8478185420804271,,0.654
Q9Y215,COLQ,Acetylcholinesterase collagenic tail peptide,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,Congenital myasthenic syndromes,0.796199449860989,,0.639
Q4FZB7,KMT5B,Histone-lysine N-methyltransferase KMT5B,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,10,"intellectual disability, autosomal dominant 51",0.7943209483524042,,0.638
Q68CZ1,RPGRIP1L,Protein fantom,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,Joubert syndrome with hepatic defect,0.7930231953177929,,0.638
Q5JVL4,EFHC1,EF-hand domain-containing protein 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,juvenile myoclonic epilepsy,0.7858434985198706,,0.636
P49459,UBE2A,Ubiquitin-conjugating enzyme E2 A,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,5,syndromic X-linked intellectual disability Nascimento type,0.7867796040270276,,0.636
O75800,ZMYND10,Zinc finger MYND domain-containing protein 10,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,primary ciliary dyskinesia,0.7822239837882315,,0.635
Q86SQ9,DHDDS,Dehydrodolichyl diphosphate synthase complex subunit DHDDS,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,9,retinitis pigmentosa 59,0.7786578489187141,,0.634
O43586,PSTPIP1,Proline-serine-threonine phosphatase-interacting protein 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,4,pyogenic arthritis-pyoderma gangrenosum-acne syndrome,0.7793785829807485,,0.634
Q8NFD5,ARID1B,AT-rich interactive domain-containing protein 1B,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,Coffin-Siris syndrome 1,0.7813407475430133,,0.634
P15104,GLUL,Glutamine synthetase,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,12,congenital brain dysgenesis due to glutamine synthetase deficiency,0.7733687702812198,,0.632
Q9NPP4,NLRC4,NLR family CARD domain-containing protein 4,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,6,periodic fever-infantile enterocolitis-autoinflammatory syndrome,0.7635956406357429,,0.629
Q15744,CEBPE,CCAAT/enhancer-binding protein epsilon,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,Recurrent infection due to specific granule deficiency,0.7619369036825959,,0.629
P10636,MAPT,Microtubule-associated protein tau,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,100,Pick disease,0.7600399335134378,,0.628
Q96CW9,NTNG2,Netrin-G2,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,3,"neurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia",0.7527757254195254,,0.626
P35716,SOX11,Transcription factor SOX-11,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,4,intellectual developmental disorder with microcephaly and with or without ocular malformations or hypogonadotropic hypogonadism,0.7470288070793535,,0.624
P48788,TNNI2,"Troponin I, fast skeletal muscle",A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,distal arthrogryposis type 2B1,0.7424838485252128,,0.623
O15350,TP73,Tumor protein p73,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,28,"ciliary dyskinesia, primary, 47, and lissencephaly",0.7409037542174439,,0.622
P12643,BMP2,Bone morphogenetic protein 2,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,21,"short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1",0.7361833785834584,,0.621
O14640,DVL1,Segment polarity protein dishevelled homolog DVL-1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,3,autosomal dominant Robinow syndrome,0.7359277384599506,,0.621
Q6EMB2,TTLL5,Tubulin polyglutamylase TTLL5,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,Cone rod dystrophy,0.72210835127064,,0.617
P41159,LEP,Leptin,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,10,obesity due to congenital leptin deficiency,0.7197450249224271,,0.616
Q8N136,DAW1,Dynein assembly factor with WD repeat domains 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,"ciliary dyskinesia, primary, 52",0.6876653910907874,,0.606
Q9BWF2,TRAIP,E3 ubiquitin-protein ligase TRAIP,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,Seckel syndrome 9,0.683878095944948,,0.605
Q4KMQ1,TPRN,Taperin,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,"hearing loss, autosomal recessive",0.6844134134291492,,0.605
Q9H6P5,TASP1,Threonine aspartase 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,10,Suleiman-El-Hattab syndrome,0.6801464403674466,,0.604
Q8IUC6,TICAM1,TIR domain-containing adapter molecule 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,8,Herpetic encephalitis,0.6364986386236531,,0.591
P50607,TUB,Tubby protein homolog,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,retinitis pigmentosa,0.631297844631827,,0.589
Q2Q1W2,TRIM71,E3 ubiquitin-protein ligase TRIM71,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,"hydrocephalus, congenital communicating, 1",0.6276048232841862,,0.588
Q9UQC2,GAB2,GRB2-associated-binding protein 2,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,10,cancer,0.6072358553557748,,0.582
Q8IWB6,TEX14,Inactive serine/threonine-protein kinase TEX14,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,spermatogenic failure 23,0.603775324929283,,0.581
P56597,NME5,Nucleoside diphosphate kinase 5,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,"ciliary dyskinesia, primary, 48, without situs inversus",0.5766985649142533,,0.573
Q13882,PTK6,Protein-tyrosine kinase 6,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,9,medullary thyroid gland carcinoma,0.5657289152364859,,0.57
P51813,BMX,Cytoplasmic tyrosine-protein kinase BMX,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,6,alopecia areata,0.5491699656070116,,0.565
O76083,PDE9A,"High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A",A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,25,coronary artery disease,0.5429744031742744,,0.563
Q96RU8,TRIB1,Tribbles homolog 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,5,neurodegenerative disease,0.5397808385585621,,0.562
Q9BVS4,RIOK2,Serine/threonine-protein kinase RIO2,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,10,neurodegenerative disease,0.539818754658029,,0.562
Q86T24,ZBTB33,Transcriptional regulator Kaiso,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,19,neurodegenerative disease,0.5355170277816887,,0.561
Q9NXF7,DCAF16,DDB1- and CUL4-associated factor 16,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,2,neurodegenerative disease,0.5251061120759617,,0.558
Q8WWN9,IPCEF1,Interactor protein for cytohesin exchange factors 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,response to tramadol,0.5225136314922196,,0.557
Q14678,KANK1,KN motif and ankyrin repeat domain-containing protein 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,5,basal cell carcinoma,0.5204468359739138,,0.556
Q8N8R7,ARL14EP,ARL14 effector protein,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,endometriosis,0.5215169504121038,,0.556
Q5TC82,RC3H1,Roquin-1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,6,"hemophagocytic lymphohistiocytosis, familial, 6",0.5161798637096334,,0.555
O43663,PRC1,Protein regulator of cytokinesis 1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,6,neurodegenerative disease,0.5139662839321523,,0.554
P49789,FHIT,Bis(5'-adenosyl)-triphosphatase,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,9,Abnormality of the skeletal system,0.505651828927915,,0.552
P48775,TDO2,"Tryptophan 2,3-dioxygenase",A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,22,Hypertryptophanemia,0.5037265368575525,,0.551
Q5UIP0,RIF1,Telomere-associated protein RIF1,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,1,neurodegenerative disease,0.5038900373620092,,0.551
Q96AT9,RPE,Ribulose-phosphate 3-epimerase,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,4,neurodegenerative disease,0.4992627094132485,,0.55
P11712,CYP2C9,Cytochrome P450 2C9,A2_pm_peripheral,HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside),0,0,,,15,cholesterol embolism,0.4868290635834234,,0.546