id,gene_symbol,protein_name,surface_class,surface_evidence,ev_map_hallmark,in_cev_map,in_vesiclepedia,in_exocarta,pdb_count,top_disease,disease_score,drug_count_approved,targetability_score P11166,SLC2A1,"Solute carrier family 2, facilitated glucose transporter member 1",A_surface,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)",1,1,,,5,encephalopathy due to GLUT1 deficiency,0.8521823225896756,,2.756 P07359,GP1BA,Platelet glycoprotein Ib alpha chain,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,22,Bernard-Soulier syndrome,0.8346884735388165,,2.75 P08514,ITGA2B,Integrin alpha-IIb,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,78,Glanzmann thrombasthenia 1,0.8224288672248264,,2.747 P14770,GP9,Platelet glycoprotein IX,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,2,Bernard-Soulier syndrome,0.8233582238860002,,2.747 P02730,SLC4A1,Band 3 anion transport protein,A_surface,"HPA protein class = Blood group antigen proteins, CD markers (cell-surface, extracellular epitope)",1,1,,,54,hereditary spherocytosis type 4,0.820137113225454,,2.746 P05106,ITGB3,Integrin beta-3,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,123,Glanzmann thrombasthenia 1,0.8208115968652424,,2.746 P16671,CD36,Platelet glycoprotein 4,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,1,platelet-type bleeding disorder 10,0.7360571429413174,,2.721 P08575,PTPRC,Receptor-type tyrosine-protein phosphatase C,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,6,immunodeficiency 104,0.7200430416648742,,2.716 P02786,TFRC,Transferrin receptor protein 1,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,22,TFRC-related combined immunodeficiency,0.623449899069336,,2.687 P05556,ITGB1,Integrin beta-1,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,22,multiple sclerosis,0.586769452063963,,2.676 P01764,IGHV3-23,Immunoglobulin heavy variable 3-23,A_surface,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)",1,1,,,6,cutaneous Leishmaniasis,0.5868213846274001,,2.676 P23083,IGHV1-2,Immunoglobulin heavy variable 1-2,A_surface,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)",1,1,,,1,cutaneous Leishmaniasis,0.5868213846274001,,2.676 P06312,IGKV4-1,Immunoglobulin kappa variable 4-1,A_surface,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)",1,1,,,10,cutaneous Leishmaniasis,0.5868213846274001,,2.676 Q12913,PTPRJ,Receptor-type tyrosine-protein phosphatase eta,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,5,neurodegenerative disease,0.54699134609967,,2.664 O00161,SNAP23,Synaptosomal-associated protein 23,A_surface,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)",1,1,,,2,neurodegenerative disease,0.5288361677964304,,2.659 P21926,CD9,CD9 antigen,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,5,diphtheria,0.5261379875719714,,2.658 P15144,ANPEP,Aminopeptidase N,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,15,cholelithiasis,0.5030146927270738,,2.651 P01871,IGHM,Immunoglobulin heavy constant mu,A_surface,"HPA protein class = Immunoglobulin genes (cell-surface, extracellular epitope)",1,1,,,30,agammaglobulinemia,0.4624778576025314,,2.639 P01833,PIGR,Polymeric immunoglobulin receptor,A_surface,"HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)",1,1,,,16,clear cell renal carcinoma,0.44260204134234277,,2.633 P17301,ITGA2,Integrin alpha-2,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,16,Abnormality of the skeletal system,0.4227839911251069,,2.627 P11169,SLC2A3,"Solute carrier family 2, facilitated glucose transporter member 3",A_surface,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)",1,1,,,7,neurodegenerative disease,0.4054698468991856,,2.622 Q08722,CD47,Leukocyte surface antigen CD47,A_surface,"HPA protein class = CD markers (cell-surface, extracellular epitope)",1,1,,,15,myelodysplastic syndrome,0.3682348506170252,,2.61 Q9HBI1,PARVB,Beta-parvin,A_surface,"HPA integral membrane protein, Plasma membrane (extracellular domain reachable)",1,1,,,3,thyroiditis,0.28021156500366357,,2.584 P02746,C1QB,Complement C1q subcomponent subunit B,A_surface,"HPA integral membrane protein, no intracellular-only localization (extracellular domain reachable)",1,1,,,11,,,,2.5