{"database": "scout", "table": "v_surface_targets", "is_view": true, "human_description_en": "where ev_map_hallmark = 1, in_cev_map = 1 and surface_class = \"A2_pm_peripheral\" sorted by targetability_score descending", "rows": [["P21333", "FLNA", "Filamin-A", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 26, "Melnick-Needles syndrome", 0.8200516896124751, null, 1.746], ["P26038", "MSN", "Moesin", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 10, "combined immunodeficiency due to moesin deficiency", 0.7157135146765757, null, 1.715], ["P84077", "ARF1", "ADP-ribosylation factor 1", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 36, "periventricular nodular heterotopia 8", 0.7173626622431929, null, 1.715], ["P07948", "LYN", "Tyrosine-protein kinase Lyn", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 6, "autoinflammatory disease, systemic, with vasculitis", 0.7119500711989845, null, 1.714], ["P61586", "RHOA", "Transforming protein RhoA", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 100, "ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies", 0.6804889074382072, null, 1.704], ["P12931", "SRC", "Proto-oncogene tyrosine-protein kinase Src", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 78, "cancer", 0.6343904000453656, null, 1.69], ["P04406", "GAPDH", "Glyceraldehyde-3-phosphate dehydrogenase", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 21, "neurodegenerative disease", 0.55307368855439, null, 1.666], ["O00194", "RAB27B", "Ras-related protein Rab-27B", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 1, "major depressive disorder", 0.4805047942947544, null, 1.644], ["P04899", "GNAI2", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 34, "ovarian granulosa cell tumor", 0.4157773365202895, null, 1.625], ["P06702", "S100A9", "Protein S100-A9", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 13, "inborn error of immunity", 0.36994943453938645, null, 1.611], ["P07996", "THBS1", "Thrombospondin-1", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 11, "autism spectrum disorder", 0.3356118729017016, null, 1.601], ["P50552", "VASP", "Vasodilator-stimulated phosphoprotein", "A2_pm_peripheral", "HPA Plasma membrane but NOT an integral membrane protein -> peripheral/cytoplasmic-leaflet (not reachable from outside)", 1, 1, null, null, 11, "neurodegenerative disease", 0.21494427179372053, null, 1.564]], "truncated": false, "filtered_table_rows_count": 12, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "gene_symbol", "protein_name", "surface_class", "surface_evidence", "ev_map_hallmark", "in_cev_map", "in_vesiclepedia", "in_exocarta", "pdb_count", "top_disease", "disease_score", "drug_count_approved", "targetability_score"], "primary_keys": [], "units": {}, "query": {"sql": "select id, gene_symbol, protein_name, surface_class, surface_evidence, ev_map_hallmark, in_cev_map, in_vesiclepedia, in_exocarta, pdb_count, top_disease, disease_score, drug_count_approved, targetability_score from v_surface_targets where \"ev_map_hallmark\" = :p0 and \"in_cev_map\" = :p1 and \"surface_class\" = :p2 order by targetability_score desc limit 51", "params": {"p0": "1", "p1": "1", "p2": "A2_pm_peripheral"}}, "facet_results": {"surface_class": {"name": "surface_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": "A2_pm_peripheral", "label": "A2_pm_peripheral", "count": 12, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1", "selected": true}], "truncated": false}, "ev_map_hallmark": {"name": "ev_map_hallmark", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 12, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?in_cev_map=1&surface_class=A2_pm_peripheral", "selected": true}], "truncated": false}, "in_cev_map": {"name": "in_cev_map", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 12, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A2_pm_peripheral", "selected": true}], "truncated": false}}, "suggested_facets": [{"name": "pdb_count", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral&_facet=pdb_count"}, {"name": "top_disease", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral&_facet=top_disease"}, {"name": "targetability_score", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&in_cev_map=1&surface_class=A2_pm_peripheral&_facet=targetability_score"}], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 54.09427406266332, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}