{"database": "scout", "table": "v_surface_targets", "is_view": true, "human_description_en": "where ev_map_hallmark = 1 and surface_class = \"A_assoc\" sorted by targetability_score descending", "rows": [["P07225", "PROS1", "Vitamin K-dependent protein S", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 3, "thrombophilia due to protein S deficiency, autosomal dominant", 0.8240418292042652, null, 1.747], ["P48740", "MASP1", "Mannan-binding lectin serine protease 1", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 9, "3MC syndrome 1", 0.8185972518103526, null, 1.746], ["Q9BWP8", "COLEC11", "Collectin-11", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 3, "3MC syndrome 2", 0.7977893521540559, null, 1.739], ["P12259", "F5", "Coagulation factor V", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 17, "thrombophilia due to activated protein C resistance", 0.7962069693286362, null, 1.739], ["P00488", "F13A1", "Coagulation factor XIII A chain", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 15, "Factor XIII subunit A deficiency", 0.7939842013132387, null, 1.738], ["O43707", "ACTN4", "Alpha-actinin-4", "A_assoc", "HPA subcellular = Focal adhesion sites (adhesion/junction, surface-associated)", 1, 1, null, null, 5, "focal segmental glomerulosclerosis 1", 0.7778533437264424, null, 1.733], ["O00187", "MASP2", "Mannan-binding lectin serine protease 2", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 10, "immunodeficiency due to MASP-2 deficiency", 0.6996393077218865, null, 1.71], ["P18206", "VCL", "Vinculin", "A_assoc", "HPA subcellular = Focal adhesion sites (adhesion/junction, surface-associated)", 1, 1, null, null, 37, "hypertrophic cardiomyopathy", 0.6924271529635582, null, 1.708], ["P02745", "C1QA", "Complement C1q subcomponent subunit A", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 11, "C1Q deficiency 1", 0.6319053256658114, null, 1.69], ["P62937", "PPIA", "Peptidyl-prolyl cis-trans isomerase A", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 100, "HIV infection", 0.6219943433906236, null, 1.687], ["P02747", "C1QC", "Complement C1q subcomponent subunit C", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 11, "C1Q deficiency", 0.6233532074390745, null, 1.687], ["Q14766", "LTBP1", "Latent-transforming growth factor beta-binding protein 1", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 1, "Abnormality of the skeletal system", 0.5142669818409414, null, 1.654], ["P05109", "S100A8", "Protein S100-A8", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 13, "inborn error of immunity", 0.37050380432141355, null, 1.611], ["O43866", "CD5L", "CD5 antigen-like", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 4, "functional neutrophil defect", 0.3529395470693119, null, 1.606], ["P48059", "LIMS1", "LIM and senescent cell antigen-like-containing domain protein 1", "A_assoc", "HPA subcellular = Focal adhesion sites (adhesion/junction, surface-associated)", 1, 1, null, null, 14, "Abruptio Placentae", 0.3236383460637068, null, 1.597], ["Q15485", "FCN2", "Ficolin-2", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 13, "hypopituitarism", 0.2753784074131916, null, 1.583], ["P01023", "A2M", "Alpha-2-macroglobulin", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 13, "refractive error", 0.2285030343788678, null, 1.569], ["P02775", "PPBP", "Platelet basic protein", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 3, "neoplasm", 0.10852035364075, null, 1.533], ["P20851", "C4BPB", "C4b-binding protein beta chain", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 0, "venous thromboembolism", 0.5408858413761136, null, 1.262], ["Q13201", "MMRN1", "Multimerin-1", "A_assoc", "HPA Predicted secreted (soluble; may form EV surface corona, not integral)", 1, 1, null, null, 0, "Parkinson disease", 0.3658959071578607, null, 1.21]], "truncated": false, "filtered_table_rows_count": 20, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "gene_symbol", "protein_name", "surface_class", "surface_evidence", "ev_map_hallmark", "in_cev_map", "in_vesiclepedia", "in_exocarta", "pdb_count", "top_disease", "disease_score", "drug_count_approved", "targetability_score"], "primary_keys": [], "units": {}, "query": {"sql": "select id, gene_symbol, protein_name, surface_class, surface_evidence, ev_map_hallmark, in_cev_map, in_vesiclepedia, in_exocarta, pdb_count, top_disease, disease_score, drug_count_approved, targetability_score from v_surface_targets where \"ev_map_hallmark\" = :p0 and \"surface_class\" = :p1 order by targetability_score desc limit 51", "params": {"p0": "1", "p1": "A_assoc"}}, "facet_results": {"surface_class": {"name": "surface_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc", "results": [{"value": "A_assoc", "label": "A_assoc", "count": 20, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1", "selected": true}], "truncated": false}, "ev_map_hallmark": {"name": "ev_map_hallmark", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc", "results": [{"value": 1, "label": 1, "count": 20, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?surface_class=A_assoc", "selected": true}], "truncated": false}, "in_cev_map": {"name": "in_cev_map", "type": "column", "hideable": false, "toggle_url": "/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc", "results": [{"value": 1, "label": 1, "count": 20, "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc&in_cev_map=1", "selected": false}], "truncated": false}}, "suggested_facets": [{"name": "surface_evidence", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc&_facet=surface_evidence"}, {"name": "pdb_count", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc&_facet=pdb_count"}, {"name": "targetability_score", "toggle_url": "https://apt-scout.org/scout/v_surface_targets.json?ev_map_hallmark=1&surface_class=A_assoc&_facet=targetability_score"}], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 79.01886198669672, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}