id,gene_symbol,protein_name,tier,evidence_priority,has_structure,surface_class,pdb_count_total,alphafold_mean_pLDDT,has_cryoEM,has_activation_state_pdb_pair,activation_state_pdb_active,activation_state_pdb_inactive,has_known_aptamer,aptamer_count_pubmed,aptamer_pmids,in_cev_map,opentargets_top_disease_name,opentargets_top_disease_score
P04275,,,Tier 1.5,0.749,1,unknown,48,75.5,1,0,,,0,0,,1,Von Willebrand disease,0.8296081124598669
P01185,,,Tier 1.5,0.585,1,unknown,5,79.44,1,0,,,0,0,,0,neurohypophyseal diabetes insipidus,0.7825664629740794
P07305,,,Tier 1.5,0.562,1,unknown,16,68.75,1,0,,,0,0,,1,open-angle glaucoma,0.2081722206162343
Q5SWA1,,,Tier 1.5,0.54,1,unknown,5,49.03,1,0,,,0,0,,0,"microcephaly, short stature, and impaired glucose metabolism 2",0.6334721902580683
O43543,,,Tier 1.5,0.529,1,unknown,16,87.12,1,0,,,0,0,,0,spermatogenic failure 50,0.5955217891975265
Q6NW34,RMP64,Ribonuclease MRP subunit P64,Tier 1.5,0.485,1,unknown,3,64.0,1,0,,,0,0,,0,anauxetic dysplasia 3,0.44914218451265836
Q32NC0,RMP24,Ribonuclease MRP protein subunit p24,Tier 1.5,0.43,1,unknown,3,74.06,1,0,,,0,0,,0,connective tissue disease,0.2652381012117321
Q9NY61,,,Tier 1.5,0.424,1,unknown,3,64.81,1,0,,,0,0,,0,skin neoplasm,0.24706398094697377
P49842,WHR1,Winged helix repair factor 1,Tier 1.5,0.361,1,unknown,5,87.44,1,0,,,0,0,,0,melanoma,0.036990092138582946