{"database": "scout", "table": "v_targets", "is_view": true, "human_description_en": "where has_activation_state_pdb_pair = 1, in_cev_map = 1 and surface_class = \"A2_pm_peripheral\" sorted by evidence_priority descending", "rows": [["P12931", "SRC", "Proto-oncogene tyrosine-protein kinase Src", "Tier 1", 0.73, 1, "A2_pm_peripheral", 78, 83.44, 0, 1, "1Y57", "2SRC", 1, 19, "40569566,39664567,38471488,35928129,35859339,34757788,34083659,33530373,32668060,30970280,28701145,26458993,25645980,23842900,22693611,22323540,18985031,18682833,12842895", 1, "cancer", 0.6343904000453656], ["P24941", "CDK2", "Cyclin-dependent kinase 2", "Tier 1", 0.652, 1, "A2_pm_peripheral", 100, 88.44, 0, 1, "1QMZ", "1HCK", 1, 24, "33981223,26972431,21616931,21059336,20394401,19320493,18495468,18186614,11071782,11106396,9826690,9826689,8606778,11566434", 1, "neurodegenerative disease", 0.37316884263655814]], "truncated": false, "filtered_table_rows_count": 2, "expanded_columns": [], "expandable_columns": [], "columns": ["id", "gene_symbol", "protein_name", "tier", "evidence_priority", "has_structure", "surface_class", "pdb_count_total", "alphafold_mean_pLDDT", "has_cryoEM", "has_activation_state_pdb_pair", "activation_state_pdb_active", "activation_state_pdb_inactive", "has_known_aptamer", "aptamer_count_pubmed", "aptamer_pmids", "in_cev_map", "opentargets_top_disease_name", "opentargets_top_disease_score"], "primary_keys": [], "units": {}, "query": {"sql": "select id, gene_symbol, protein_name, tier, evidence_priority, has_structure, surface_class, pdb_count_total, alphafold_mean_pLDDT, has_cryoEM, has_activation_state_pdb_pair, activation_state_pdb_active, activation_state_pdb_inactive, has_known_aptamer, aptamer_count_pubmed, aptamer_pmids, in_cev_map, opentargets_top_disease_name, opentargets_top_disease_score from v_targets where \"has_activation_state_pdb_pair\" = :p0 and \"in_cev_map\" = :p1 and \"surface_class\" = :p2 order by evidence_priority desc limit 51", "params": {"p0": "1", "p1": "1", "p2": "A2_pm_peripheral"}}, "facet_results": {"has_structure": {"name": "has_structure", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral&has_structure=1", "selected": false}], "truncated": false}, "tier": {"name": "tier", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": "Tier 1", "label": "Tier 1", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral&tier=Tier+1", "selected": false}], "truncated": false}, "has_activation_state_pdb_pair": {"name": "has_activation_state_pdb_pair", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?in_cev_map=1&surface_class=A2_pm_peripheral", "selected": true}], "truncated": false}, "has_known_aptamer": {"name": "has_known_aptamer", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral&has_known_aptamer=1", "selected": false}], "truncated": false}, "surface_class": {"name": "surface_class", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": "A2_pm_peripheral", "label": "A2_pm_peripheral", "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1", "selected": true}], "truncated": false}, "in_cev_map": {"name": "in_cev_map", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 1, "label": 1, "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&surface_class=A2_pm_peripheral", "selected": true}], "truncated": false}, "has_cryoEM": {"name": "has_cryoEM", "type": "column", "hideable": false, "toggle_url": "/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral", "results": [{"value": 0, "label": 0, "count": 2, "toggle_url": "https://apt-scout.org/scout/v_targets.json?has_activation_state_pdb_pair=1&in_cev_map=1&surface_class=A2_pm_peripheral&has_cryoEM=0", "selected": false}], "truncated": false}}, "suggested_facets": [], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 1329.034024849534, "source": "apt-scout automated curation pipeline (E. Dohi, NCNP) \u2014 values harvested from public databases; raw source stored per target", "source_url": "https://apt-scout.org", "license": "CC BY 4.0", "license_url": "https://creativecommons.org/licenses/by/4.0/"}