db_stats: 13

Every headline number on apt-scout, computed LIVE from the database at build time, each tagged with an EVIDENCE GRADE so harvested/keyword/predicted figures are never confused with verified ones. Grades: defined-set (the curated target universe) · harvested (mechanically pulled from a public DB) · predicted (AlphaFold model, not experimental) · keyword-unverified (PubMed co-mention, may be false positive) · detected (present in a dataset, not a curated subset) · human-curated · source-derived (re-derived from the original paper's supplementary) · verbatim-verified (a source quote backs each value).

Data license: CC BY 4.0 · Data source: apt-scout automated curation pipeline (E. Dohi, NCNP) — values harvested from public databases; raw source stored per target

This data as json

rowid	ord	metric	value	grade	definition	source
13	13	cell-surface / ecto targets (PREDICTED EV-surface accessible)	1136	predicted	Integral membrane / ecto-domain proteins (CD markers, GPCRs, ion channels, integral membrane). EV biogenesis normally preserves topology so the ectodomain is PREDICTED to face the EV surface. NOT a measurement: HPA reports cellular (not EV) localization; lipid asymmetry can partially flip (PS via scramblase on activated/platelet EVs); cytoplasmic proteins can attach as a corona. Confirm by protease-protection / intact-EV surface labelling / immuno-EM.	HPA subcellular + protein class (Thul 2017 / Uhlén 2015)