target_layer3_interaction
Data license: CC BY 4.0 · Data source: apt-scout automated curation pipeline (E. Dohi, NCNP) — values harvested from public databases; raw source stored per target
7,197 rows
This data as json, CSV (advanced)
Suggested facets: has_known_aptamer, recorded_utc (date)
| target_id ▼ | ppi_count | drug_count_approved | drug_count_clinical | aptamer_count_pubmed | aptamer_count_aptagen | antibody_count_hpa | has_known_aptamer | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|
| A0A075B5G3 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A075B5G3", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A075B5G3", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A075B5G3", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.877697+00:00 | |||
| A0A075B6T6 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A075B6T6", "gene_symbol": "TRAV12-2", "protein_name": "T cell receptor alpha variable 12-2", "pubmed_by_symbol": {"query": "(TRAV12-2) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor alpha variable 12-2\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRAV12-2", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRAV12-2", "Gene synonym": [], "Ensembl": "ENSG00000211789", "Uniprot": ["A0A075B6T6"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "5", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A075B6T6", "gene_symbol": "TRAV12-2"}} | 2026-05-27T10:45:01.499307+00:00 | |||
| A0A087X1C5 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A087X1C5", "gene_symbol": "CYP2D7", "protein_name": "Cytochrome P450 2D7", "pubmed_by_symbol": {"query": "(CYP2D7) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Cytochrome P450 2D7\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=CYP2D7", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "CYP2D7", "Gene synonym": ["CYP2D", "CYP2D@", "CYP2D7P", "CYP2D7P1"], "Ensembl": "ENSG00000205702", "Uniprot": [], "Protein class": ["Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Not detected", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A087X1C5", "gene_symbol": "CYP2D7"}} | 2026-05-27T10:45:03.013391+00:00 | |||
| A0A087X2I1 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A087X2I1", "gene_symbol": "PSMC6", "protein_name": "26S proteasome regulatory subunit 10B", "pubmed_by_symbol": {"query": "(PSMC6) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"26S proteasome regulatory subunit 10B\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=PSMC6", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "PSMC6", "Gene synonym": ["p42", "RPT5"], "Ensembl": "ENSG00000100519", "Uniprot": ["P62333"], "Protein class": ["Essential proteins", "Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA042823"], "Subcellular location": ["Nucleoplasm", "Plasma membrane", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A087X2I1", "gene_symbol": "PSMC6"}} | 2026-05-27T10:45:01.919454+00:00 | |||
| A0A0A6YX08 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0A6YX08", "gene_symbol": "Trbj2-2", "protein_name": null, "pubmed_by_symbol": {"query": "(Trbj2-2) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=Trbj2-2", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBJ2-2", "Gene synonym": ["TCRBJ2S2", "TRBJ22"], "Ensembl": "ENSG00000211765", "Uniprot": [], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0A6YX08", "gene_symbol": "Trbj2-2"}} | 2026-05-27T10:45:02.450614+00:00 | |||
| A0A0B4J1J9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0B4J1J9", "gene_symbol": "Trav11", "protein_name": null, "pubmed_by_symbol": {"query": "(Trav11) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=Trav11", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRAV1-1", "Gene synonym": ["TCRAV1S1", "TCRAV7S1", "TRAV11"], "Ensembl": "ENSG00000255569", "Uniprot": ["A0A0B4J248"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "13", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0B4J1J9", "gene_symbol": "Trav11"}} | 2026-05-27T10:45:01.587584+00:00 | |||
| A0A0B4J271 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0B4J271", "gene_symbol": "TRAV12-3", "protein_name": "T cell receptor alpha variable 12-3", "pubmed_by_symbol": {"query": "(TRAV12-3) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor alpha variable 12-3\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRAV12-3", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRAV12-3", "Gene synonym": ["TCRAV12S3", "TCRAV2S2", "TRAV123"], "Ensembl": "ENSG00000211794", "Uniprot": ["A0A0B4J271"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "10", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0B4J271", "gene_symbol": "TRAV12-3"}} | 2026-05-27T10:45:01.537746+00:00 | |||
| A0A0B4J2E0 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0B4J2E0", "gene_symbol": "TRBV12-4", "protein_name": "T cell receptor beta variable 12-4", "pubmed_by_symbol": {"query": "(TRBV12-4) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor beta variable 12-4\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRBV12-4", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBV12-4", "Gene synonym": ["TCRBV12S4", "TCRBV8S2A1T", "TRBV124"], "Ensembl": "ENSG00000276953", "Uniprot": ["A0A0B4J2E0"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "44", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0B4J2E0", "gene_symbol": "TRBV12-4"}} | 2026-05-27T10:45:01.641624+00:00 | |||
| A0A0B4J2F0 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0B4J2F0", "gene_symbol": "PIGBOS1", "protein_name": "Protein PIGBOS1", "pubmed_by_symbol": {"query": "(PIGBOS1) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Protein PIGBOS1\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=PIGBOS1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "PIGBOS1", "Gene synonym": [], "Ensembl": "ENSG00000225973", "Uniprot": ["A0A0B4J2F0"], "Protein class": ["Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0B4J2F0", "gene_symbol": "PIGBOS1"}} | 2026-05-27T10:45:03.013539+00:00 | |||
| A0A0C4DH28 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0C4DH28", "gene_symbol": "TRGV4", "protein_name": "T cell receptor gamma variable 4", "pubmed_by_symbol": {"query": "(TRGV4) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor gamma variable 4\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRGV4", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRGV4", "Gene synonym": ["TCRGV4", "V1S4"], "Ensembl": "ENSG00000211698", "Uniprot": ["A0A0C4DH28"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0C4DH28", "gene_symbol": "TRGV4"}} | 2026-05-27T10:45:01.831283+00:00 | |||
| A0A0C5B5G6 | 0 | 1 | 0 | 1 | {"aptamer": {"uniprot_id": "A0A0C5B5G6", "gene_symbol": "MT-RNR1", "protein_name": "Mitochondrial-derived peptide MOTS-c", "pubmed_by_symbol": {"query": "(MT-RNR1) AND (aptamer OR SELEX)", "count": 1, "pmids": ["35311942"]}, "pubmed_by_name": {"query": "(\"Mitochondrial-derived peptide MOTS-c\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=MT-RNR1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A0C5B5G6", "gene_symbol": "MT-RNR1"}} | 2026-05-27T10:45:02.465922+00:00 | |||
| A0A0E3EAY4 | 0 | 12 | 0 | 1 | {"aptamer": {"uniprot_id": "A0A0E3EAY4", "gene_symbol": "env", "protein_name": "Envelope glycoprotein gp160", "pubmed_by_symbol": {"query": "(env) AND (aptamer OR SELEX)", "count": 12, "pmids": ["36576612", "29464116", "29217761", "22379083", "18776229", "18569791", "16146716", "16043495", "16013840", "12498773", "11024283", "9713975"]}, "pubmed_by_name": {"query": "(\"Envelope glycoprotein gp160\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=env", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "ERVW-1", "Gene synonym": ["envW", "ERVWE1", "HERV-7q", "HERV-W", "HERV-W-ENV", "HERVW"], "Ensembl": "ENSG00000242950", "Uniprot": ["Q9UQF0"], "Protein class": ["Essential proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "8", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0E3EAY4", "gene_symbol": "env"}} | 2026-05-27T10:45:02.453609+00:00 | |||
| A0A0G2JG46 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0G2JG46", "gene_symbol": "Traj18", "protein_name": null, "pubmed_by_symbol": {"query": "(Traj18) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=Traj18", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRAJ18", "Gene synonym": [], "Ensembl": "ENSG00000211871", "Uniprot": [], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Group enriched", "RNA tissue specificity score": "5", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0G2JG46", "gene_symbol": "Traj18"}} | 2026-05-27T10:45:02.451733+00:00 | |||
| A0A0G2LB96 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0G2LB96", "gene_symbol": "Trbv29", "protein_name": null, "pubmed_by_symbol": {"query": "(Trbv29) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=Trbv29", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBV29-1", "Gene synonym": ["TCRBV29S1", "TCRBV4S1A1T", "TRBV291"], "Ensembl": "ENSG00000232869", "Uniprot": ["A0A5B7"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "5", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0G2LB96", "gene_symbol": "Trbv29"}} | 2026-05-27T10:45:01.581140+00:00 | |||
| A0A0J9YX06 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0J9YX06", "gene_symbol": "TRBJ1-2", "protein_name": "T cell receptor beta joining 1-2", "pubmed_by_symbol": {"query": "(TRBJ1-2) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor beta joining 1-2\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRBJ1-2", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBJ1-2", "Gene synonym": ["TCRBJ1S2", "TRBJ12"], "Ensembl": "ENSG00000282420", "Uniprot": ["A0A0J9YX06"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "11", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0J9YX06", "gene_symbol": "TRBJ1-2"}} | 2026-05-27T10:45:02.452271+00:00 | |||
| A0A0K0K1A5 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0K0K1A5", "gene_symbol": "TRBV6-5", "protein_name": "T cell receptor beta variable 6-5", "pubmed_by_symbol": {"query": "(TRBV6-5) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor beta variable 6-5\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRBV6-5", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBV6-5", "Gene synonym": ["TCRBV13S1", "TCRBV6S5", "TRBV65"], "Ensembl": "ENSG00000211721", "Uniprot": ["A0A0K0K1A5"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "11", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0K0K1A5", "gene_symbol": "TRBV6-5"}} | 2026-05-27T10:45:01.545698+00:00 | |||
| A0A0K2S4Q6 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0K2S4Q6", "gene_symbol": "CD300H", "protein_name": "Protein CD300H", "pubmed_by_symbol": {"query": "(CD300H) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Protein CD300H\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=CD300H", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "CD300H", "Gene synonym": [], "Ensembl": "ENSG00000284690", "Uniprot": ["A0A0K2S4Q6"], "Protein class": ["Essential proteins", "Predicted membrane proteins", "Predicted secreted proteins"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": "Secreted to blood", "Secretome function": "No annotated function", "uniprot_id": "A0A0K2S4Q6", "gene_symbol": "CD300H"}} | 2026-05-27T10:45:03.013708+00:00 | |||
| A0A0L7RG06 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0L7RG06", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A0L7RG06", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A0L7RG06", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.817458+00:00 | |||
| A0A0U5IHY9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0U5IHY9", "gene_symbol": "HLA-DQB1", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-DQB1) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-DQB1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-DQB1", "Gene synonym": ["CELIAC1", "HLA-DQB", "IDDM1"], "Ensembl": "ENSG00000179344", "Uniprot": [], "Protein class": ["Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["HPA013667"], "Subcellular location": ["Golgi apparatus", "Rods & Rings"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A0U5IHY9", "gene_symbol": "HLA-DQB1"}} | 2026-05-27T10:45:01.768418+00:00 | |||
| A0A0U5Q247 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A0U5Q247", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A0U5Q247", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A0U5Q247", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.789511+00:00 | |||
| A0A140T913 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A140T913", "gene_symbol": "HLA-A", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-A) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-A", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-A", "Gene synonym": [], "Ensembl": "ENSG00000206503", "Uniprot": ["P04439"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["CAB078470"], "Subcellular location": ["Golgi apparatus", "Plasma membrane"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A140T913", "gene_symbol": "HLA-A"}} | 2026-05-27T10:45:01.805557+00:00 | |||
| A0A1B0GTW7 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A1B0GTW7", "gene_symbol": "CIROP", "protein_name": "Ciliated left-right organizer metallopeptidase", "pubmed_by_symbol": {"query": "(CIROP) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Ciliated left-right organizer metallopeptidase\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=CIROP", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "CIROP", "Gene synonym": ["LMLN2"], "Ensembl": "ENSG00000283654", "Uniprot": ["A0A1B0GTW7"], "Protein class": ["Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins"], "Disease involvement": ["Disease variant", "Heterotaxy"], "RNA tissue specificity": "Not detected", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A1B0GTW7", "gene_symbol": "CIROP"}} | 2026-05-27T10:45:02.466071+00:00 | |||
| A0A1B0GX56 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A1B0GX56", "gene_symbol": "TRDV1", "protein_name": "T cell receptor delta variable 1", "pubmed_by_symbol": {"query": "(TRDV1) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor delta variable 1\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRDV1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRDV1", "Gene synonym": ["hDV101S1"], "Ensembl": "ENSG00000211804", "Uniprot": ["A0A1B0GX56"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "16", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A1B0GX56", "gene_symbol": "TRDV1"}} | 2026-05-27T10:45:01.590437+00:00 | |||
| A0A1B0GXE1 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A1B0GXE1", "gene_symbol": "TRBV6-4", "protein_name": null, "pubmed_by_symbol": {"query": "(TRBV6-4) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRBV6-4", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBV6-4", "Gene synonym": ["TCRBV13S5", "TCRBV6S4", "TRBV64"], "Ensembl": "ENSG00000211713", "Uniprot": ["A0A1B0GX49"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A1B0GXE1", "gene_symbol": "TRBV6-4"}} | 2026-05-27T10:45:01.611445+00:00 | |||
| A0A2K6KCS5 | 0 | 1 | 0 | 1 | {"aptamer": {"uniprot_id": "A0A2K6KCS5", "gene_symbol": "YTHDC1", "protein_name": "YTH domain-containing family protein", "pubmed_by_symbol": {"query": "(YTHDC1) AND (aptamer OR SELEX)", "count": 1, "pmids": ["41430607"]}, "pubmed_by_name": {"query": "(\"YTH domain-containing family protein\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=YTHDC1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "YTHDC1", "Gene synonym": ["KIAA1966", "YT521", "YT521-B"], "Ensembl": "ENSG00000083896", "Uniprot": ["Q96MU7"], "Protein class": ["Essential proteins", "Plasma proteins", "Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA036462"], "Subcellular location": ["Nucleoplasm", "Plasma membrane"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A2K6KCS5", "gene_symbol": "YTHDC1"}} | 2026-05-27T10:45:02.419383+00:00 | |||
| A0A2R7Z5J3 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A2R7Z5J3", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A2R7Z5J3", "_error": "<urlopen error [Errno -3] Temporary failure in name resolution>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A2R7Z5J3", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.722026+00:00 | |||
| A0A340WVW7 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A340WVW7", "gene_symbol": "RPS23", "protein_name": "Small ribosomal subunit protein uS12", "pubmed_by_symbol": {"query": "(RPS23) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Small ribosomal subunit protein uS12\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=RPS23", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "RPS23", "Gene synonym": ["S23", "uS12"], "Ensembl": "ENSG00000186468", "Uniprot": ["P62266"], "Protein class": ["Disease related genes", "Essential proteins", "Predicted intracellular proteins", "Ribosomal proteins"], "Disease involvement": ["Deafness", "Disease variant", "Dwarfism"], "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA054853", "HPA071639"], "Subcellular location": ["Endoplasmic reticulum", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A340WVW7", "gene_symbol": "RPS23"}} | 2026-05-27T10:45:01.507463+00:00 | |||
| A0A3B3ITX3 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A3B3ITX3", "gene_symbol": "GNAI1", "protein_name": null, "pubmed_by_symbol": {"query": "(GNAI1) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=GNAI1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "GNAI1", "Gene synonym": [], "Ensembl": "ENSG00000127955", "Uniprot": ["P63096"], "Protein class": ["Cancer-related genes", "Disease related genes", "Plasma proteins", "Predicted intracellular proteins"], "Disease involvement": ["Cancer-related genes", "Disease variant", "Epilepsy", "Intellectual disability"], "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["CAB022449", "HPA042141"], "Subcellular location": ["Nucleoplasm", "Nucleoli", "Golgi apparatus", "Centriolar satellite", "Centrosome", "Basal body", "Cytosol", "Principal piece"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A3B3ITX3", "gene_symbol": "GNAI1"}} | 2026-05-27T10:45:02.418687+00:00 | |||
| A0A583ZB34 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A583ZB34", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A583ZB34", "_error": "<urlopen error [Errno -3] Temporary failure in name resolution>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A583ZB34", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.824247+00:00 | |||
| A0A592 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A592", "gene_symbol": "TCRBV6S1A1N1", "protein_name": null, "pubmed_by_symbol": {"query": "(TCRBV6S1A1N1) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TCRBV6S1A1N1", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBV7-3", "Gene synonym": ["TCRBV6S1A1N1", "TCRBV7S3", "TRBV73"], "Ensembl": "ENSG00000211714", "Uniprot": ["A0A075B6L6"], "Protein class": ["Predicted intracellular proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A592", "gene_symbol": "TCRBV6S1A1N1"}} | 2026-05-27T10:45:01.675382+00:00 | |||
| A0A5B9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A5B9", "gene_symbol": "TRBC2", "protein_name": "T cell receptor beta constant 2", "pubmed_by_symbol": {"query": "(TRBC2) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"T cell receptor beta constant 2\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=TRBC2", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "TRBC2", "Gene synonym": ["TCRBC2"], "Ensembl": "ENSG00000211772", "Uniprot": ["A0A5B9"], "Protein class": ["Predicted membrane proteins", "T-cell receptor genes"], "Disease involvement": null, "RNA tissue specificity": "Group enriched", "RNA tissue specificity score": "5", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A5B9", "gene_symbol": "TRBC2"}} | 2026-05-27T10:45:01.478510+00:00 | |||
| A0A5C2GQT9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A5C2GQT9", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A5C2GQT9", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A5C2GQT9", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.393818+00:00 | |||
| A0A5H2UYS3 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A5H2UYS3", "gene_symbol": "HLA-A", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-A) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-A", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-A", "Gene synonym": [], "Ensembl": "ENSG00000206503", "Uniprot": ["P04439"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["CAB078470"], "Subcellular location": ["Golgi apparatus", "Plasma membrane"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A5H2UYS3", "gene_symbol": "HLA-A"}} | 2026-05-27T10:45:01.785247+00:00 | |||
| A0A5P9VSM6 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A5P9VSM6", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A5P9VSM6", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A5P9VSM6", "_note": "no gene symbol"}} | 2026-05-27T10:45:02.455433+00:00 | |||
| A0A5P9VSM8 | 0 | 9 | 0 | 1 | {"aptamer": {"uniprot_id": "A0A5P9VSM8", "gene_symbol": null, "protein_name": "Replicase", "pubmed_by_name": {"query": "(\"Replicase\") AND (aptamer OR SELEX)", "count": 9, "pmids": ["38027068", "34660818", "26336964", "23596299", "22819625", "21440279", "20980498", "16314308", "7578085"]}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A5P9VSM8", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A5P9VSM8", "_note": "no gene symbol"}} | 2026-05-27T10:45:02.454130+00:00 | |||
| A0A678ZMW1 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A678ZMW1", "gene_symbol": "HLA-B", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-B) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-B", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-B", "Gene synonym": ["AS"], "Ensembl": "ENSG00000234745", "Uniprot": ["P01889"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["CAB015418"], "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A678ZMW1", "gene_symbol": "HLA-B"}} | 2026-05-27T10:45:01.738466+00:00 | |||
| A0A6B7FTL9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A6B7FTL9", "gene_symbol": "HLA-B", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-B) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-B", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-B", "Gene synonym": ["AS"], "Ensembl": "ENSG00000234745", "Uniprot": ["P01889"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["CAB015418"], "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A6B7FTL9", "gene_symbol": "HLA-B"}} | 2026-05-27T10:45:01.750637+00:00 | |||
| A0A6B7HFJ9 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A6B7HFJ9", "gene_symbol": "HLA-B", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-B) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-B", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-B", "Gene synonym": ["AS"], "Ensembl": "ENSG00000234745", "Uniprot": ["P01889"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["CAB015418"], "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A6B7HFJ9", "gene_symbol": "HLA-B"}} | 2026-05-27T10:45:01.741661+00:00 | |||
| A0A6I9HGD1 | 0 | 3 | 0 | 1 | {"aptamer": {"uniprot_id": "A0A6I9HGD1", "gene_symbol": "ACTB", "protein_name": null, "pubmed_by_symbol": {"query": "(ACTB) AND (aptamer OR SELEX)", "count": 3, "pmids": ["40413753", "38783134", "34598060"]}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=ACTB", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "ACTB", "Gene synonym": [], "Ensembl": "ENSG00000075624", "Uniprot": ["P60709"], "Protein class": ["Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins"], "Disease involvement": ["Deafness", "Disease variant", "Dystonia", "Intellectual disability"], "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["CAB002621", "HPA041264", "HPA041271"], "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A6I9HGD1", "gene_symbol": "ACTB"}} | 2026-05-27T10:45:01.531863+00:00 | |||
| A0A6J0Y1Z7 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A6J0Y1Z7", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A6J0Y1Z7", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A6J0Y1Z7", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.656358+00:00 | |||
| A0A6S7XV52 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A6S7XV52", "gene_symbol": "HLA-A", "protein_name": null, "pubmed_by_symbol": {"query": "(HLA-A) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=HLA-A", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "HLA-A", "Gene synonym": [], "Ensembl": "ENSG00000206503", "Uniprot": ["P04439"], "Protein class": ["Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": ["Cancer-related genes"], "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["CAB078470"], "Subcellular location": ["Golgi apparatus", "Plasma membrane"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0A6S7XV52", "gene_symbol": "HLA-A"}} | 2026-05-27T10:45:01.784014+00:00 | |||
| A0A9P1NJI6 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0A9P1NJI6", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0A9P1NJI6", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0A9P1NJI6", "_note": "no gene symbol"}} | 2026-05-27T10:45:02.454562+00:00 | |||
| A0AVK6 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0AVK6", "gene_symbol": "E2F8", "protein_name": "Transcription factor E2F8", "pubmed_by_symbol": {"query": "(E2F8) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Transcription factor E2F8\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=E2F8", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "E2F8", "Gene synonym": ["FLJ23311"], "Ensembl": "ENSG00000129173", "Uniprot": ["A0AVK6"], "Protein class": ["Predicted intracellular proteins", "Transcription factors"], "Disease involvement": null, "RNA tissue specificity": "Tissue enhanced", "RNA tissue specificity score": null, "Antibody": ["HPA064882", "HPA076614"], "Subcellular location": ["Nucleoplasm", "Nucleoli", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0AVK6", "gene_symbol": "E2F8"}} | 2026-05-27T10:45:03.013888+00:00 | |||
| A0AVT1 | 0 | 1 | 0 | 1 | {"aptamer": {"uniprot_id": "A0AVT1", "gene_symbol": "UBA6", "protein_name": "Ubiquitin-like modifier-activating enzyme 6", "pubmed_by_symbol": {"query": "(UBA6) AND (aptamer OR SELEX)", "count": 1, "pmids": ["41981644"]}, "pubmed_by_name": {"query": "(\"Ubiquitin-like modifier-activating enzyme 6\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=UBA6", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "UBA6", "Gene synonym": ["FLJ10808", "UBE1L2"], "Ensembl": "ENSG00000033178", "Uniprot": ["A0AVT1"], "Protein class": ["Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA037001"], "Subcellular location": ["Nucleoplasm", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0AVT1", "gene_symbol": "UBA6"}} | 2026-05-27T10:45:01.558235+00:00 | |||
| A0FGR8 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0FGR8", "gene_symbol": "ESYT2", "protein_name": "Extended synaptotagmin-2", "pubmed_by_symbol": {"query": "(ESYT2) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Extended synaptotagmin-2\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=ESYT2", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "ESYT2", "Gene synonym": ["CHR2SYT", "FAM62B", "KIAA1228"], "Ensembl": "ENSG00000117868", "Uniprot": ["A0FGR8"], "Protein class": ["Plasma proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA002132", "HPA070823"], "Subcellular location": ["Plasma membrane", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0FGR8", "gene_symbol": "ESYT2"}} | 2026-05-27T10:45:02.153081+00:00 | |||
| A0JLT2 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0JLT2", "gene_symbol": "MED19", "protein_name": "Mediator of RNA polymerase II transcription subunit 19", "pubmed_by_symbol": {"query": "(MED19) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Mediator of RNA polymerase II transcription subunit 19\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=MED19", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "MED19", "Gene synonym": ["LCMR1"], "Ensembl": "ENSG00000156603", "Uniprot": ["A0JLT2"], "Protein class": ["Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA039912", "HPA040860"], "Subcellular location": ["Nucleoplasm", "Nuclear bodies"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0JLT2", "gene_symbol": "MED19"}} | 2026-05-27T10:45:02.316872+00:00 | |||
| A0JNW5 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0JNW5", "gene_symbol": "BLTP3B", "protein_name": "Bridge-like lipid transfer protein family member 3B", "pubmed_by_symbol": {"query": "(BLTP3B) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Bridge-like lipid transfer protein family member 3B\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=BLTP3B", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "BLTP3B", "Gene synonym": ["KIAA0701", "SHIP164", "UHRF1BP1L"], "Ensembl": "ENSG00000111647", "Uniprot": ["A0JNW5"], "Protein class": ["Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Low tissue specificity", "RNA tissue specificity score": null, "Antibody": ["HPA039671", "HPA075150"], "Subcellular location": ["Nucleoplasm", "Vesicles", "Cytosol"], "Secretome location": null, "Secretome function": null, "uniprot_id": "A0JNW5", "gene_symbol": "BLTP3B"}} | 2026-05-27T10:45:02.466261+00:00 | |||
| A0JP26 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0JP26", "gene_symbol": "POTEB3", "protein_name": "POTE ankyrin domain family member B3", "pubmed_by_symbol": {"query": "(POTEB3) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"POTE ankyrin domain family member B3\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=POTEB3", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "POTEB3", "Gene synonym": [], "Ensembl": "ENSG00000278522", "Uniprot": ["A0JP26"], "Protein class": ["Predicted intracellular proteins"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "19", "Antibody": null, "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0JP26", "gene_symbol": "POTEB3"}} | 2026-05-27T10:45:02.466453+00:00 | |||
| A0N8J3 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0N8J3", "gene_symbol": null, "protein_name": null, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=A0N8J3", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"uniprot_id": "A0N8J3", "_note": "no gene symbol"}} | 2026-05-27T10:45:01.584672+00:00 | |||
| A0PJK1 | 0 | 0 | 0 | 0 | {"aptamer": {"uniprot_id": "A0PJK1", "gene_symbol": "SLC5A10", "protein_name": "Sodium/mannose cotransporter SLC5A10", "pubmed_by_symbol": {"query": "(SLC5A10) AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "pubmed_by_name": {"query": "(\"Sodium/mannose cotransporter SLC5A10\") AND (aptamer OR SELEX)", "count": 0, "pmids": []}, "ribocentre": {"url": "https://www.ribocentre-aptamer.com/?s=SLC5A10", "_error": "<urlopen error [Errno -2] Name or service not known>"}}, "open_targets_drugs": null, "hpa_antibodies": {"Gene": "SLC5A10", "Gene synonym": ["SGLT5"], "Ensembl": "ENSG00000154025", "Uniprot": ["A0PJK1"], "Protein class": ["Metabolic proteins", "Predicted membrane proteins", "Transporters"], "Disease involvement": null, "RNA tissue specificity": "Tissue enriched", "RNA tissue specificity score": "13", "Antibody": ["HPA052014"], "Subcellular location": null, "Secretome location": null, "Secretome function": null, "uniprot_id": "A0PJK1", "gene_symbol": "SLC5A10"}} | 2026-05-27T10:45:03.014102+00:00 |
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CREATE TABLE target_layer3_interaction ( target_id TEXT PRIMARY KEY, ppi_count INTEGER, drug_count_approved INTEGER, drug_count_clinical INTEGER, aptamer_count_pubmed INTEGER, aptamer_count_aptagen INTEGER, antibody_count_hpa INTEGER, has_known_aptamer INTEGER, -- 0 / 1 (sort axis for narrow down) raw_json TEXT, recorded_utc TEXT ); CREATE INDEX idx_l3_aptamer ON target_layer3_interaction(has_known_aptamer); CREATE INDEX idx_l3_drug ON target_layer3_interaction(drug_count_approved);