EV-Map conserved proteome (Rai & Greening 2025)

The complete EV-Map conserved molecular signature (Rai & Greening 2025, Nat Cell Biol 10.1038/s41556-025-01795-7): 182 conserved EV-hallmark proteins + 42 non-EV (lipoprotein-network) proteins. in_apt_scout = 1 if the protein is an apt-scout target (104 of the 182 EV-hallmark + 25 of the 42 non-EV are; the rest are reference-only, outside apt-scout's target universe). Source: paper Supplementary Table 7.

Data license: CC BY 4.0 · Data source: apt-scout automated curation pipeline (E. Dohi, NCNP) — values harvested from public databases; raw source stored per target

gene_name
Gene symbol.
feature
EV-hallmark (conserved EV) or non-EV (lipoprotein-network).
category
EV-Map conservation category (1/2/3/Rest).
in_apt_scout
1 if this protein is an apt-scout target.
apt_scout_uniprot
apt-scout target UniProt (if in_apt_scout=1).

4 rows where category = "Category 2"

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in_apt_scout 2

feature 1

category 1

  • Category 2 · 4 ✖
Link rowid ▼ gene_name feature category misev_marker entrezgene_id pevs_median in_apt_scout apt_scout_uniprot
36 36 SERPINA4 non-EV Category 2   5267 23.04960691 1 P29622
131 131 IGFALS non-EV Category 2   3483 23.25044831 1 P35858
218 218 AFM non-EV Category 2   173 23.86740073 1 P43652
224 224 A1BG non-EV Category 2   1 25.43002533 0  

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CREATE TABLE ev_map_conserved (gene_name TEXT, feature TEXT, category TEXT,
             misev_marker TEXT, entrezgene_id TEXT, pevs_median TEXT,
             in_apt_scout INTEGER, apt_scout_uniprot TEXT);