EV-Map conserved proteome (Rai & Greening 2025)

The complete EV-Map conserved molecular signature (Rai & Greening 2025, Nat Cell Biol 10.1038/s41556-025-01795-7): 182 conserved EV-hallmark proteins + 42 non-EV (lipoprotein-network) proteins. in_apt_scout = 1 if the protein is an apt-scout target (104 of the 182 EV-hallmark + 25 of the 42 non-EV are; the rest are reference-only, outside apt-scout's target universe). Source: paper Supplementary Table 7.

Data license: CC BY 4.0 · Data source: apt-scout automated curation pipeline (E. Dohi, NCNP) — values harvested from public databases; raw source stored per target

gene_name
Gene symbol.
feature
EV-hallmark (conserved EV) or non-EV (lipoprotein-network).
category
EV-Map conservation category (1/2/3/Rest).
in_apt_scout
1 if this protein is an apt-scout target.
apt_scout_uniprot
apt-scout target UniProt (if in_apt_scout=1).

7 rows where category = "Rest"

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in_apt_scout 2

feature 1

category 1

  • Rest · 7 ✖
Link rowid ▼ gene_name feature category misev_marker entrezgene_id pevs_median in_apt_scout apt_scout_uniprot
32 32 SERPINF1 non-EV Rest   5176 22.03354595 1 P36955
87 87 LUM non-EV Rest   4060 22.41106809 1 P51884
158 158 FBLN1 non-EV Rest   2192 21.85894765 0  
161 161 F13B non-EV Rest   2165 22.01963417 0  
164 164 F10 non-EV Rest   2159 22.10768229 1 P00742
170 170 CPB2 non-EV Rest   1361 22.13340968 1 Q96IY4
174 174 CLEC3B non-EV Rest   7123 22.20646531 1 P05452

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CREATE TABLE ev_map_conserved (gene_name TEXT, feature TEXT, category TEXT,
             misev_marker TEXT, entrezgene_id TEXT, pevs_median TEXT,
             in_apt_scout INTEGER, apt_scout_uniprot TEXT);