kd_measurements: 44
This data as json
| id | source_pmid | aptamer_name | target_name_canonical | target_uniprot | kd_value | kd_unit | kd_log10_molar | binding_constant_type | aptamer_chemistry | aptamer_modifications | assay_method | assay_buffer | assay_ph | assay_temperature_k | assay_cations | verification_status | source_db | source_record_id | aptamer_seq | aptamer_seq_raw | measurement_class | verbatim_quote | seq_source | tier | sequence_status | pi_provenance_flag | include_in_gold | doi |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 44 | 24129312 | 8A-35 | IL-8 | P10145 | 1.72e-12 | M | -11.764 | Kd | 2'F-RNA | 2'-fluoro-pyrimidine modified | SPR | HBST running buffer (10 mM HEPES, pH 7.4, 150 mM NaCl, and 0.005% Tween 20) | 7.4 | 298.0 | verified | step2c_literal_v3 | r00292 | GGGGGCUUAUCAUUCCAUUUAGUGUUAUGAUAACC | 5'-GGGGGCUUAUCAUUCCAUUUAGUGUUAUGAUAACC-3' | intrinsic | | 8A-35 | 5.78 x 10 4 | 9.95 x 10 -8 | 1.72 x 10 -12 | 2.80 | 3.11 x 10 1 | | original | v4 | verified_in_text_or_SI | True | 10.1016/j.biomaterials.2013.09.107 |