kd_measurements: 49
This data as json
| id | source_pmid | aptamer_name | target_name_canonical | target_uniprot | kd_value | kd_unit | kd_log10_molar | binding_constant_type | aptamer_chemistry | aptamer_modifications | assay_method | assay_buffer | assay_ph | assay_temperature_k | assay_cations | verification_status | source_db | source_record_id | aptamer_seq | aptamer_seq_raw | measurement_class | verbatim_quote | seq_source | tier | sequence_status | pi_provenance_flag | include_in_gold | doi |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 49 | 24723743 | PDGF-specific aptamer | PDGF-BB | P01127 | 1.2e-09 | M | -8.921 | Kd | DNA | 3'-3'-linked thymidine nucleotide ([3'T]); thiolated 5'-end | microcantilever | PBSM buffer (10.1 mM Na2HPO4, 1.8 mM KH2PO4, 137 mM NaCl, 2.7 mM KCl, and 1 mM MgCl2, pH 7.4) | 7.4 | 292.15 | 1.0 | verified | step2c_literal_v3 | r00312 | intrinsic | K d , as shown in Fig. 10, decreased from approximately 12 × 10 -10 M to 5 × 10 -10 M as the temperature changed from 19 to 37 ◦ C. | v4 | pending_manual_figure | True | 10.1016/j.snb.2012.02.045 |