target_layer1_structure: A0A0B4J271
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A0B4J271 | 12 | 12 | 92.56 | 1 | 4 | 1 | 1 | 0 | {"pdb": {"uniprot_id": "A0A0B4J271", "pdb_count_total": 12, "pdb_count_detailed": 12, "entries": [{"pdb_id": "4WWK", "title": "Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin", "keywords": "IMMUNE SYSTEM", "resolution": 3.1, "method": "X-RAY DIFFRACTION", "deposit_date": "2014-11-11T00:00:00.000+00:00", "release_date": "2016-02-03T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "TCR Alpha Chain-TRAV12-3", "length": 209}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}, {"comp_id": "(15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]", "chem_id": "JLS"}], "primary_citation": {"title": "Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2016, "authors": ["Le Nours, J.", "Praveena, T.", "Pellicci, D.G.", "Gherardin, N.A.", "Ross, F.J.", "Lim, R.T."]}, "related_emdb": []}, {"pdb_id": "5C07", "title": "1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA", "keywords": "IMMUNE SYSTEM", "resolution": 2.11, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 199}], "ligands": [{"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5C08", "title": "1E6 TCR in Complex with HLA-A0e carrying RQWGPDPAAV", "keywords": "IMMUNE SYSTEM", "resolution": 2.332, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 191}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5C09", "title": "HLA class I histocompatibility antigen", "keywords": "IMMUNE SYSTEM", "resolution": 2.475, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 200}], "ligands": [{"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5C0A", "title": "1E6 TCR in complex with HLA-A02 carrying MVW peptide", "keywords": "IMMUNE SYSTEM", "resolution": 2.46, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 197}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5C0B", "title": "1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI", "keywords": "IMMUNE SYSTEM", "resolution": 2.03, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 199}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "TETRAETHYLENE GLYCOL", "chem_id": "PG4"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5C0C", "title": "1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA", "keywords": "IMMUNE SYSTEM", "resolution": 1.974, "method": "X-RAY DIFFRACTION", "deposit_date": "2015-06-12T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "1E6 TCR Alpha Chain", "length": 200}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "TETRAETHYLENE GLYCOL", "chem_id": "PG4"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}], "primary_citation": {"title": "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Cole, D.K.", "Bulek, A.M.", "Dolton, G.", "Schauenberg, A.J.", "Szomolay, B.", "Rittase, W."]}, "related_emdb": []}, {"pdb_id": "5HYJ", "title": "1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA", "keywords": "IMMUNE SYSTEM", "resolution": 3.06, "method": "X-RAY DIFFRACTION", "deposit_date": "2016-02-01T00:00:00.000+00:00", "release_date": "2016-05-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "4", "chains": ["D", "I"], "description": "Human T-cell Receptor, Class I, Light alpha Chain", "length": 193}], "ligands": [], "primary_citation": {"title": "A \"hotspot\" for autoimmune T cells in type 1 diabetes.", "doi": null, "pmid": null, "journal": "J Clin Invest", "year": 2016, "authors": ["Stadinski, B.D.", "Obst, R.", "Huseby, E.S."]}, "related_emdb": []}, {"pdb_id": "6JXR", "title": "Structure of human T cell receptor-CD3 complex", "keywords": "IMMUNE SYSTEM", "resolution": 3.7, "method": "ELECTRON MICROSCOPY", "deposit_date": "2019-04-24T00:00:00.000+00:00", "release_date": "2019-09-11T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "5", "chains": ["m"], "description": "T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant", "length": 252}], "ligands": [], "primary_citation": {"title": "Structural basis of assembly of the human T cell receptor-CD3 complex.", "doi": null, "pmid": null, "journal": "Nature", "year": 2019, "authors": ["Zheng, L.", "Lin, J.", "Zhang, B.", "Zhu, Y.", "Li, N.", "Xie, S."]}, "related_emdb": ["EMD-9895"]}, {"pdb_id": "7FJD", "title": "Cryo-EM structure of a membrane protein(WT)", "keywords": "IMMUNE SYSTEM", "resolution": 3.2, "method": "ELECTRON MICROSCOPY", "deposit_date": "2021-08-03T00:00:00.000+00:00", "release_date": "2022-07-27T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "5", "chains": ["m"], "description": "T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant", "length": 272}], "ligands": [{"comp_id": "CHOLESTEROL", "chem_id": "CLR"}], "primary_citation": {"title": "Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.", "doi": null, "pmid": null, "journal": "Mol Cell", "year": 2022, "authors": ["Chen, Y.", "Zhu, Y.", "Li, X.", "Gao, W.", "Zhen, Z.", "Huang, B."]}, "related_emdb": ["EMD-31618"]}, {"pdb_id": "7FJE", "title": "Cryo-EM structure of a membrane protein(LL)", "keywords": "IMMUNE SYSTEM", "resolution": 3.0, "method": "ELECTRON MICROSCOPY", "deposit_date": "2021-08-03T00:00:00.000+00:00", "release_date": "2022-07-27T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "5", "chains": ["m"], "description": "T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant", "length": 272}], "ligands": [{"comp_id": "CHOLESTEROL", "chem_id": "CLR"}], "primary_citation": {"title": "Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.", "doi": null, "pmid": null, "journal": "Mol Cell", "year": 2022, "authors": ["Chen, Y.", "Zhu, Y.", "Li, X.", "Gao, W.", "Zhen, Z.", "Huang, B."]}, "related_emdb": ["EMD-31619"]}, {"pdb_id": "7FJF", "title": "Cryo-EM structure of a membrane protein(CS)", "keywords": "IMMUNE SYSTEM", "resolution": 3.1, "method": "ELECTRON MICROSCOPY", "deposit_date": "2021-08-03T00:00:00.000+00:00", "release_date": "2022-07-27T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "5", "chains": ["m"], "description": "T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant", "length": 272}], "ligands": [{"comp_id": "CHOLEST-5-EN-3-YL HYDROGEN SULFATE", "chem_id": "C3S"}], "primary_citation": {"title": "Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.", "doi": null, "pmid": null, "journal": "Mol Cell", "year": 2022, "authors": ["Chen, Y.", "Zhu, Y.", "Li, X.", "Gao, W.", "Zhen, Z.", "Huang, B."]}, "related_emdb": ["EMD-31620"]}]}, "alphafold": {"uniprot_id": "A0A0B4J271", "model_count": 1, "models": [{"entryId": "AF-A0A0B4J271-F1", "uniprotAccession": "A0A0B4J271", "uniprotDescription": "T cell receptor alpha variable 12-3", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 92.56, "modelCreatedDate": "2025-08-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A0B4J271-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A0B4J271-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A0B4J271-F1-predicted_aligned_error_v6.png"}]}, "emdb": {"uniprot_id": "A0A0B4J271", "emdb_count": 4, "entries": [{"emdb_id": "EMD-9895", "title": null, "resolution_A": null, "deposit_date": "2019-04-24T00:00:00", "release_date": "2019-08-21T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-31618", "title": null, "resolution_A": null, "deposit_date": "2021-08-03T00:00:00", "release_date": "2022-07-27T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-31619", "title": null, "resolution_A": null, "deposit_date": "2021-08-03T00:00:00", "release_date": "2022-07-27T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-31620", "title": null, "resolution_A": null, "deposit_date": "2021-08-03T00:00:00", "release_date": "2022-07-27T00:00:00", "method": "electron microscopy"}]}} | 2026-05-27T10:45:01.537684+00:00 |