target_layer1_structure: A0A583ZB34
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A583ZB34 | 9 | 9 | 84.38 | 1 | 0 | 0 | 1 | 0 | {"pdb": {"uniprot_id": "A0A583ZB34", "pdb_count_total": 9, "pdb_count_detailed": 9, "entries": [{"pdb_id": "7OW3", "title": "Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVVGAGGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 2.46, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-06-16T00:00:00.000+00:00", "release_date": "2022-07-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D", "G", "J"], "description": "MHC class I antigen", "length": 275}], "ligands": [], "primary_citation": {"title": "Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Poole, A.", "Karuppiah, V.", "Hartt, A.", "Haidar, J.N.", "Moureau, S.", "Dobrzycki, T."]}, "related_emdb": []}, {"pdb_id": "7OW4", "title": "Crystal structure of HLA-A*11:01 in complex with KRAS G12D peptide (VVVGADGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 1.81, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-06-16T00:00:00.000+00:00", "release_date": "2022-07-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D", "G", "J"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Poole, A.", "Karuppiah, V.", "Hartt, A.", "Haidar, J.N.", "Moureau, S.", "Dobrzycki, T."]}, "related_emdb": []}, {"pdb_id": "7OW5", "title": "Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVVGAGGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 2.58, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-06-16T00:00:00.000+00:00", "release_date": "2022-07-20T00:00:00.000+00:00", "my_uniprot_chains": 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receptor targeting a KRASG12D cancer neoantigen", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Poole, A.", "Karuppiah, V.", "Hartt, A.", "Haidar, J.N.", "Moureau, S.", "Dobrzycki, T."]}, "related_emdb": []}, {"pdb_id": "7PB2", "title": "Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 3.41, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-07-30T00:00:00.000+00:00", "release_date": "2022-07-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "F"], "description": "MHC class I antigen", "length": 276}], "ligands": [], "primary_citation": {"title": "Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Poole, A.", "Karuppiah, V.", "Hartt, A.", "Haidar, J.N.", "Moureau, S.", "Dobrzycki, T."]}, "related_emdb": []}, {"pdb_id": "8RYN", "title": "Structure of S2 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide", "keywords": "IMMUNE SYSTEM", "resolution": 1.97, "method": "X-RAY DIFFRACTION", "deposit_date": "2024-02-09T00:00:00.000+00:00", "release_date": "2024-09-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 276}], "ligands": [], "primary_citation": {"title": "Broadening alloselectivity of T cell receptors by structure guided engineering.", "doi": null, "pmid": null, "journal": "Sci Rep", "year": 2024, "authors": ["Karuppiah, V.", "Sangani, D.", "Whaley, L.", "Pengelly, R.", "Uluocak, P.", "Carreira, R.J."]}, "related_emdb": []}, {"pdb_id": "8RYQ", "title": "Structure of S8-9F3 TCR in complex with HLA-A*11:01 bound to ELFSYLIEK peptide", "keywords": "IMMUNE SYSTEM", "resolution": 2.49, "method": "X-RAY DIFFRACTION", "deposit_date": "2024-02-09T00:00:00.000+00:00", "release_date": "2024-09-04T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "F"], "description": "MHC class I antigen", "length": 276}], "ligands": [], "primary_citation": {"title": "Broadening alloselectivity of T cell receptors by structure guided engineering.", "doi": null, "pmid": null, "journal": "Sci Rep", "year": 2024, "authors": ["Karuppiah, V.", "Sangani, D.", "Whaley, L.", "Pengelly, R.", "Uluocak, P.", "Carreira, R.J."]}, "related_emdb": []}, {"pdb_id": "8WTE", "title": "Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 2.17, "method": "X-RAY DIFFRACTION", "deposit_date": "2023-10-18T00:00:00.000+00:00", "release_date": "2024-05-01T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "3", "chains": ["E", "H"], "description": "MHC class I antigen (Fragment)", "length": 275}], "ligands": [], "primary_citation": {"title": "Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen.", "doi": null, "pmid": null, "journal": "Commun Biol", "year": 2024, "authors": ["Zhang, M.", "Xu, W.", "Luo, L.", "Guan, F.", "Wang, X.", "Zhu, P."]}, "related_emdb": []}, {"pdb_id": "8WUL", "title": "Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)", "keywords": "IMMUNE SYSTEM", "resolution": 2.36, "method": "X-RAY DIFFRACTION", "deposit_date": "2023-10-20T00:00:00.000+00:00", "release_date": "2024-05-01T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "3", "chains": ["I", "L", "O", "R"], "description": "MHC class I antigen", "length": 274}], "ligands": [], "primary_citation": {"title": "Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen.", "doi": null, "pmid": null, "journal": "Commun Biol", "year": 2024, "authors": ["Zhang, M.", "Xu, W.", "Luo, L.", "Guan, F.", "Wang, X.", "Zhu, P."]}, "related_emdb": []}]}, "alphafold": {"uniprot_id": "A0A583ZB34", "model_count": 1, "models": [{"entryId": "AF-A0A583ZB34-F1", "uniprotAccession": "A0A583ZB34", "uniprotDescription": "MHC class I antigen", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 84.38, "modelCreatedDate": "2022-06-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A583ZB34-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A583ZB34-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A583ZB34-F1-predicted_aligned_error_v6.png"}]}, "emdb": {"uniprot_id": "A0A583ZB34", "emdb_count": 0, "entries": []}} | 2026-05-27T10:45:01.824198+00:00 |