home / scout / target_layer1_structure

target_layer1_structure: A0A5H2UYS3

Layer 1 STRUCTURE. Source: RCSB PDB + AlphaFold + EMDB. Full upstream record in raw_json.

This data as json

target_id pdb_count_total pdb_count_detailed pdb_best_resolution_A alphafold_mean_pLDDT alphafold_model_count emdb_count has_cryoEM has_xray has_NMR raw_json recorded_utc
A0A5H2UYS3 20 20   85.25 1 0 0 1 0 {"pdb": {"uniprot_id": "A0A5H2UYS3", "pdb_count_total": 20, "pdb_count_detailed": 20, "entries": [{"pdb_id": "6XQA", "title": "Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus", "keywords": "IMMUNE SYSTEM", "resolution": 2.16, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-07-09T00:00:00.000+00:00", "release_date": "2021-04-14T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 278}], "ligands": [{"comp_id": "MAGNESIUM ION", "chem_id": "MG"}], "primary_citation": {"title": "CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2021, "authors": ["Hensen, L.", "Illing, P.T.", "Bridie Clemens, E.", "Nguyen, T.H.O.", "Koutsakos, M.", "van de Sandt, C.E."]}, "related_emdb": []}, {"pdb_id": "7EJL", "title": "Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-2) spike protein", "keywords": "IMMUNE SYSTEM", "resolution": 1.89, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-04-02T00:00:00.000+00:00", "release_date": "2022-01-26T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 281}], "ligands": [], "primary_citation": {"title": "Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2.", "doi": null, "pmid": null, "journal": "Commun Biol", "year": 2021, "authors": ["Shimizu, K.", "Iyoda, T.", "Sanpei, A.", "Nakazato, H.", "Okada, M.", "Ueda, S."]}, "related_emdb": []}, {"pdb_id": "7EJM", "title": "Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-229E) spike protein", "keywords": "IMMUNE SYSTEM", "resolution": 1.71, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-04-02T00:00:00.000+00:00", "release_date": "2022-01-26T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 281}], "ligands": [], "primary_citation": {"title": "Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2.", "doi": null, "pmid": null, "journal": "Commun Biol", "year": 2021, "authors": ["Shimizu, K.", "Iyoda, T.", "Sanpei, A.", "Nakazato, H.", "Okada, M.", "Ueda, S."]}, "related_emdb": []}, {"pdb_id": "7EJN", "title": "Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-HKU1) spike protein", "keywords": "IMMUNE SYSTEM", "resolution": 2.11, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-04-02T00:00:00.000+00:00", "release_date": "2022-01-26T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 281}], "ligands": [], "primary_citation": {"title": "Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2.", "doi": null, "pmid": null, "journal": "Commun Biol", "year": 2021, "authors": ["Shimizu, K.", "Iyoda, T.", "Sanpei, A.", "Nakazato, H.", "Okada, M.", "Ueda, S."]}, "related_emdb": []}, {"pdb_id": "7JYU", "title": "Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus", "keywords": "IMMUNE SYSTEM", "resolution": 2.75, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-01T00:00:00.000+00:00", "release_date": "2021-04-14T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 278}], "ligands": [{"comp_id": "MAGNESIUM ION", "chem_id": "MG"}], "primary_citation": {"title": "CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2021, "authors": ["Hensen, L.", "Illing, P.T.", "Bridie Clemens, E.", "Nguyen, T.H.O.", "Koutsakos, M.", "van de Sandt, C.E."]}, "related_emdb": []}, {"pdb_id": "7JYV", "title": "Crystal Structure of HLA A*2402 in complex with YFSPIRVTF, an 9-mer influenza epitope", "keywords": "IMMUNE SYSTEM", "resolution": 1.51, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-01T00:00:00.000+00:00", "release_date": "2021-04-14T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 278}], "ligands": [{"comp_id": "MAGNESIUM ION", "chem_id": "MG"}], "primary_citation": {"title": "CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2021, "authors": ["Hensen, L.", "Illing, P.T.", "Bridie Clemens, E.", "Nguyen, T.H.O.", "Koutsakos, M.", "van de Sandt, C.E."]}, "related_emdb": []}, {"pdb_id": "7JYW", "title": "Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope", "keywords": "IMMUNE SYSTEM", "resolution": 2.9, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-01T00:00:00.000+00:00", "release_date": "2021-04-14T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 278}], "ligands": [{"comp_id": "CALCIUM ION", "chem_id": "CA"}, {"comp_id": "SODIUM ION", "chem_id": "NA"}, {"comp_id": "NICKEL (II) ION", "chem_id": "NI"}], "primary_citation": {"title": "CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2021, "authors": ["Hensen, L.", "Illing, P.T.", "Bridie Clemens, E.", "Nguyen, T.H.O.", "Koutsakos, M.", "van de Sandt, C.E."]}, "related_emdb": []}, {"pdb_id": "7JYX", "title": "Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza", "keywords": "IMMUNE SYSTEM", "resolution": 2.95, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-01T00:00:00.000+00:00", "release_date": "2021-04-14T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 278}], "ligands": [], "primary_citation": {"title": "CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2021, "authors": ["Hensen, L.", "Illing, P.T.", "Bridie Clemens, E.", "Nguyen, T.H.O.", "Koutsakos, M.", "van de Sandt, C.E."]}, "related_emdb": []}, {"pdb_id": "7K80", "title": "KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide", "keywords": "IMMUNE SYSTEM", "resolution": 2.4, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-24T00:00:00.000+00:00", "release_date": "2020-12-09T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "FORMIC ACID", "chem_id": "FMT"}, {"comp_id": "ACETATE ION", "chem_id": "ACT"}, {"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}], "primary_citation": {"title": "The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.", "doi": null, "pmid": null, "journal": "J Immunol", "year": 2021, "authors": ["Saunders, P.M.", "MacLachlan, B.J.", "Widjaja, J.", "Wong, S.C.", "Oates, C.V.L.", "Rossjohn, J."]}, "related_emdb": []}, {"pdb_id": "7K81", "title": "KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide", "keywords": "IMMUNE SYSTEM", "resolution": 2.0, "method": "X-RAY DIFFRACTION", "deposit_date": "2020-09-24T00:00:00.000+00:00", "release_date": "2020-12-09T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}], "primary_citation": {"title": "The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.", "doi": null, "pmid": null, "journal": "J Immunol", "year": 2021, "authors": ["Saunders, P.M.", "MacLachlan, B.J.", "Widjaja, J.", "Wong, S.C.", "Oates, C.V.L.", "Rossjohn, J."]}, "related_emdb": []}, {"pdb_id": "7MJA", "title": "HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide", "keywords": "IMMUNE SYSTEM", "resolution": 1.69, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-04-19T00:00:00.000+00:00", "release_date": "2021-08-18T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "HLA class I histocompatibility antigen", "length": 283}], "ligands": [{"comp_id": "GLYCEROL", "chem_id": "GOL"}], "primary_citation": {"title": "Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.", "doi": null, "pmid": null, "journal": "Nature", "year": 2021, "authors": ["Yarmarkovich, M.", "Marshall, Q.F.", "Warrington, J.M.", "Premaratne, R.", "Farrel, A.", "Groff, D."]}, "related_emdb": []}, {"pdb_id": "7NMD", "title": "Human Major Histocompatibility Complex A24 Allele presenting QLPRLFPLL", "keywords": "IMMUNE SYSTEM", "resolution": 2.25, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-02-23T00:00:00.000+00:00", "release_date": "2022-09-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "DI(HYDROXYETHYL)ETHER", "chem_id": "PEG"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Human Major Histocompatibility Complex A24 Allele presenting QLPRLFPLL", "doi": null, "pmid": null, "journal": "To be published", "year": null, "authors": ["Rizkallahp, P.J.", "Sewell, A.K.", "Cole, D.K."]}, "related_emdb": []}, {"pdb_id": "7NME", "title": "Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR", "keywords": "IMMUNE SYSTEM", "resolution": 2.2, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-02-23T00:00:00.000+00:00", "release_date": "2022-09-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "BTB"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}], "primary_citation": {"title": "Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR", "doi": null, "pmid": null, "journal": "To be published", "year": null, "authors": ["Rizkallahp, P.J.", "Sewell, A.K.", "Cole, D.K.", "Wall, A."]}, "related_emdb": []}, {"pdb_id": "7NMF", "title": "Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form", "keywords": "IMMUNE SYSTEM", "resolution": 2.98, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-02-23T00:00:00.000+00:00", "release_date": "2022-09-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "2-(N-MORPHOLINO)-ETHANESULFONIC ACID", "chem_id": "MES"}, {"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form", "doi": null, "pmid": null, "journal": "To be published", "year": null, "authors": ["Rizkallahp, P.J.", "Sewell, A.K.", "Cole, D.K.", "Wall, A."]}, "related_emdb": []}, {"pdb_id": "7NMG", "title": "Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR", "keywords": "IMMUNE SYSTEM", "resolution": 2.48, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-02-23T00:00:00.000+00:00", "release_date": "2022-09-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 276}], "ligands": [{"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID", "chem_id": "EPE"}, {"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}], "primary_citation": {"title": "Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR", "doi": null, "pmid": null, "journal": "To be published", "year": null, "authors": ["Rizkallahp, P.J.", "Sewell, A.K.", "Cole, D.K.", "Wall, A."]}, "related_emdb": []}, {"pdb_id": "7WT3", "title": "Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide", "keywords": "IMMUNE SYSTEM", "resolution": 1.88765498464, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-02-03T00:00:00.000+00:00", "release_date": "2022-06-22T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 277}], "ligands": [{"comp_id": "2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "TRS"}, {"comp_id": "ACETATE ION", "chem_id": "ACT"}, {"comp_id": "ZINC ION", "chem_id": "ZN"}, {"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}], "primary_citation": {"title": "Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.", "doi": null, "pmid": null, "journal": "J Biological Chem", "year": 2022, "authors": ["Asa, M.", "Morita, D.", "Kuroha, J.", "Mizutani, T.", "Mori, N.", "Mikami, B."]}, "related_emdb": []}, {"pdb_id": "7WT4", "title": "Crystal structure of HLA-A*2402 complexed with 8-mer Influenza PB1 peptide", "keywords": "IMMUNE SYSTEM", "resolution": 1.89459140677, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-02-03T00:00:00.000+00:00", "release_date": "2022-06-22T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D"], "description": "MHC class I antigen", "length": 277}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "ZINC ION", "chem_id": "ZN"}, {"comp_id": "2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "TRS"}, {"comp_id": "ACETATE ION", "chem_id": "ACT"}], "primary_citation": {"title": "Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.", "doi": null, "pmid": null, "journal": "J Biological Chem", "year": 2022, "authors": ["Asa, M.", "Morita, D.", "Kuroha, J.", "Mizutani, T.", "Mori, N.", "Mikami, B."]}, "related_emdb": []}, {"pdb_id": "8RJ5", "title": "P1-15 T-cell Receptor bound to HLA A*2402-NF9 pMHC complex", "keywords": "IMMUNE SYSTEM", "resolution": 3.02, "method": "X-RAY DIFFRACTION", "deposit_date": "2023-12-20T00:00:00.000+00:00", "release_date": "2025-01-01T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "F"], "description": "MHC class I antigen", "length": 277}], "ligands": [], "primary_citation": {"title": "NF9 T-cell Receptor bound to HLA A*2402-NF9 pMHC complex (Paper Pending)", "doi": null, "pmid": null, "journal": "To be published", "year": null, "authors": ["Motozono, C.", "Wall, A.", "Sewell, A.K.", "Rizkallah, P.J.", "Fuller, A."]}, "related_emdb": []}, {"pdb_id": "8SBK", "title": "Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A).", "keywords": "IMMUNE SYSTEM", "resolution": 1.8, "method": "X-RAY DIFFRACTION", "deposit_date": "2023-04-03T00:00:00.000+00:00", "release_date": "2023-12-06T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 283}], "ligands": [{"comp_id": "1,2-ETHANEDIOL", "chem_id": "EDO"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.", "doi": null, "pmid": null, "journal": "Sci Immunol", "year": 2023, "authors": ["Sun, Y.", "Florio, T.J.", "Gupta, S.", "Young, M.C.", "Marshall, Q.F.", "Garfinkle, S.E."]}, "related_emdb": []}, {"pdb_id": "8SBL", "title": "Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI", "keywords": "IMMUNE SYSTEM", "resolution": 3.0, "method": "X-RAY DIFFRACTION", "deposit_date": "2023-04-03T00:00:00.000+00:00", "release_date": "2023-12-06T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "D", "G", "J"], "description": "MHC class I antigen", "length": 283}], "ligands": [], "primary_citation": {"title": "Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.", "doi": null, "pmid": null, "journal": "Sci Immunol", "year": 2023, "authors": ["Sun, Y.", "Florio, T.J.", "Gupta, S.", "Young, M.C.", "Marshall, Q.F.", "Garfinkle, S.E."]}, "related_emdb": []}]}, "alphafold": {"uniprot_id": "A0A5H2UYS3", "model_count": 1, "models": [{"entryId": "AF-A0A5H2UYS3-F1", "uniprotAccession": "A0A5H2UYS3", "uniprotDescription": "MHC class I antigen", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 85.25, "modelCreatedDate": "2022-06-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A5H2UYS3-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A5H2UYS3-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A5H2UYS3-F1-predicted_aligned_error_v6.png"}]}, "emdb": {"uniprot_id": "A0A5H2UYS3", "emdb_count": 0, "entries": []}} 2026-05-27T10:45:01.785188+00:00
Powered by Datasette · Queries took 2.203ms