target_layer1_structure: A0A5P9VSM8
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A5P9VSM8 | 7 | 7 | 0 | 7 | 1 | 0 | 0 | {"pdb": {"uniprot_id": "A0A5P9VSM8", "pdb_count_total": 7, "pdb_count_detailed": 7, "entries": [{"pdb_id": "8TW4", "title": "TCR in nanodisc ND-I", "keywords": "IMMUNE SYSTEM", "resolution": 3.3, "method": "ELECTRON MICROSCOPY", "deposit_date": "2023-08-20T00:00:00.000+00:00", "release_date": "2024-10-02T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "6", "chains": ["X", "Y"], "description": "T-cell surface glycoprotein CD3 zeta chain,RNA-directed RNA polymerase L", "length": 412}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}, {"comp_id": "CHOLESTEROL", "chem_id": "CLR"}], "primary_citation": {"title": "The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex.", "doi": null, "pmid": null, "journal": "bioRxiv", "year": 2024, "authors": ["Notti, R.Q.", "Yi, F.", "Heissel, S.", "Bush, M.W.", "Molvi, Z.", "Das, P."]}, "related_emdb": ["EMD-41658"]}, {"pdb_id": "8V38", "title": "Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1)", "keywords": "MEMBRANE PROTEIN", "resolution": 3.5, "method": "ELECTRON MICROSCOPY", "deposit_date": "2023-11-27T00:00:00.000+00:00", "release_date": "2024-06-26T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B"], "description": "SID1 transmembrane family member 1,RNA-directed RNA polymerase L", "length": 1097}], "ligands": [], "primary_citation": {"title": "Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain.", "doi": null, "pmid": null, "journal": "Life Sci Alliance", "year": 2024, "authors": ["Navratna, V.", "Kumar, A.", "Rana, J.K.", "Mosalaganti, S."]}, "related_emdb": ["EMD-42943"]}, {"pdb_id": "9OQP", "title": "Human pannexin 1 channel with 1mM mefloquine", "keywords": "TRANSPORT PROTEIN", "resolution": 2.62, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-05-21T00:00:00.000+00:00", "release_date": "2025-12-24T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B", "C", "D", "E", "F", "G"], "description": "Pannexin-1,RNA-directed RNA polymerase L", "length": 691}], "ligands": [{"comp_id": "(11S,12R)-Mefloquine", "chem_id": "A1A1V"}], "primary_citation": {"title": "Structural basis of PANX1 permeation and positive modulation by mefloquine.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2025, "authors": ["Li, Y.", "Ruan, Z.", "Lee, J.", "Orozco, I.J.", "Zhou, E.", "Du, J."]}, "related_emdb": ["EMD-70769"]}, {"pdb_id": "9OQQ", "title": "Human pannexin 1 channel W74A mutant with 10mM ATP", "keywords": "TRANSPORT PROTEIN", "resolution": 3.25, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-05-21T00:00:00.000+00:00", "release_date": "2025-12-24T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B", "C", "D", "E", "F", "G"], "description": "Pannexin-1,RNA-directed RNA polymerase L chimera", "length": 691}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}], "primary_citation": {"title": "Structural basis of PANX1 permeation and positive modulation by mefloquine.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2025, "authors": ["Li, Y.", "Ruan, Z.", "Lee, J.", "Orozco, I.J.", "Zhou, E.", "Du, J."]}, "related_emdb": ["EMD-70770"]}, {"pdb_id": "9P3U", "title": "Zebrafish TRPM5 E337A mutant with 5mM calcium and 0.5mM CBTA", "keywords": "TRANSFERASE", "resolution": 2.75, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-06-14T00:00:00.000+00:00", "release_date": "2026-01-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B", "C", "D"], "description": "RNA-directed RNA polymerase L,Transient receptor potential cation channel subfamily M member 5", "length": 1475}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}, {"comp_id": "CALCIUM ION", "chem_id": "CA"}, {"comp_id": "Tigogenin", "chem_id": "A1CGZ"}, {"comp_id": "5-chloro-N-[(5-chloro-1,3-thiazol-2-yl)methyl]-1,2-benzothiazol-6-amine", "chem_id": "A1CGW"}, {"comp_id": "(2R)-2-(hydroxymethyl)-4-{[(10xi,13xi,22xi,25R)-5beta,14beta,17beta-spirostan-3b", "chem_id": "A1CG0"}], "primary_citation": {"title": "A single allosteric site merges activation, modulation and inhibition in TRPM5.", "doi": null, "pmid": null, "journal": "Nat Chem Biol", "year": 2026, "authors": ["Ruan, Z.", "Lee, J.", "Li, Y.", "Orozco, I.J.", "Du, J.", "Lu, W."]}, "related_emdb": ["EMD-71255"]}, {"pdb_id": "9P3V", "title": "Zebrafish TRPM5 Q771A mutant with 5mM calcium and 0.5mM CBTA", "keywords": "TRANSFERASE", "resolution": 2.75, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-06-14T00:00:00.000+00:00", "release_date": "2026-01-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B", "C", "D"], "description": "RNA-directed RNA polymerase L,Transient receptor potential cation channel subfamily M member 5", "length": 1475}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}, {"comp_id": "CALCIUM ION", "chem_id": "CA"}, {"comp_id": "Tigogenin", "chem_id": "A1CGZ"}, {"comp_id": "5-chloro-N-[(5-chloro-1,3-thiazol-2-yl)methyl]-1,2-benzothiazol-6-amine", "chem_id": "A1CGW"}, {"comp_id": "(2R)-2-(hydroxymethyl)-4-{[(10xi,13xi,22xi,25R)-5beta,14beta,17beta-spirostan-3b", "chem_id": "A1CG0"}], "primary_citation": {"title": "A single allosteric site merges activation, modulation and inhibition in TRPM5.", "doi": null, "pmid": null, "journal": "Nat Chem Biol", "year": 2026, "authors": ["Ruan, Z.", "Lee, J.", "Li, Y.", "Orozco, I.J.", "Du, J.", "Lu, W."]}, "related_emdb": ["EMD-71256"]}, {"pdb_id": "9P3W", "title": "Zebrafish TRPM5 Q771A mutant with 5mM calcium", "keywords": "TRANSFERASE", "resolution": 2.85, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-06-14T00:00:00.000+00:00", "release_date": "2026-01-07T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B", "C", "D"], "description": "RNA-directed RNA polymerase L,Transient receptor potential cation channel subfamily M member 5", "length": 1475}], "ligands": [{"comp_id": "2-acetamido-2-deoxy-beta-D-glucopyranose", "chem_id": "NAG"}, {"comp_id": "CALCIUM ION", "chem_id": "CA"}, {"comp_id": "Tigogenin", "chem_id": "A1CGZ"}, {"comp_id": "(2R)-2-(hydroxymethyl)-4-{[(10xi,13xi,22xi,25R)-5beta,14beta,17beta-spirostan-3b", "chem_id": "A1CG0"}], "primary_citation": {"title": "A single allosteric site merges activation, modulation and inhibition in TRPM5.", "doi": null, "pmid": null, "journal": "Nat Chem Biol", "year": 2026, "authors": ["Ruan, Z.", "Lee, J.", "Li, Y.", "Orozco, I.J.", "Du, J.", "Lu, W."]}, "related_emdb": ["EMD-71257"]}]}, "alphafold": {"uniprot_id": "A0A5P9VSM8", "model_count": 0, "_note": "no AlphaFold prediction"}, "emdb": {"uniprot_id": "A0A5P9VSM8", "emdb_count": 7, "entries": [{"emdb_id": "EMD-41658", "title": null, "resolution_A": null, "deposit_date": "2023-08-20T00:00:00", "release_date": "2024-10-02T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-42943", "title": null, "resolution_A": null, "deposit_date": "2023-11-27T00:00:00", "release_date": "2024-06-26T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-70769", "title": null, "resolution_A": null, "deposit_date": "2025-05-21T00:00:00", "release_date": "2025-12-24T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-70770", "title": null, "resolution_A": null, "deposit_date": "2025-05-21T00:00:00", "release_date": "2025-12-24T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-71255", "title": null, "resolution_A": null, "deposit_date": "2025-06-14T00:00:00", "release_date": "2026-01-07T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-71256", "title": null, "resolution_A": null, "deposit_date": "2025-06-14T00:00:00", "release_date": "2026-01-07T00:00:00", "method": "electron microscopy"}, {"emdb_id": "EMD-71257", "title": null, "resolution_A": null, "deposit_date": "2025-06-14T00:00:00", "release_date": "2026-01-07T00:00:00", "method": "electron microscopy"}]}} | 2026-05-27T10:45:02.454077+00:00 |