target_layer1_structure: A0A6S7XV52
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A6S7XV52 | 6 | 6 | 85.12 | 1 | 1 | 1 | 1 | 0 | {"pdb": {"uniprot_id": "A0A6S7XV52", "pdb_count_total": 6, "pdb_count_detailed": 6, "entries": [{"pdb_id": "7SQP", "title": "Single chain trimer HLA-A*02:01 (Y108C) with HPV.16 E7 peptide YMLDLQPETTDL", "keywords": "IMMUNE SYSTEM", "resolution": 2.53, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-11-05T00:00:00.000+00:00", "release_date": "2022-11-23T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera", "length": 427}], "ligands": [], "primary_citation": {"title": "Effects of HLA single chain trimer design on peptide presentation and stability.", "doi": null, "pmid": null, "journal": "Front Immunol", "year": 2023, "authors": ["Finton, K.A.K.", "Rupert, P.B.", "Friend, D.J.", "Dinca, A.", "Lovelace, E.S.", "Buerger, M."]}, "related_emdb": []}, {"pdb_id": "7SR0", "title": "Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET", "keywords": "IMMUNE SYSTEM", "resolution": 2.54, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-11-07T00:00:00.000+00:00", "release_date": "2022-11-23T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera", "length": 424}], "ligands": [{"comp_id": "PHOSPHATE ION", "chem_id": "PO4"}], "primary_citation": {"title": "Effects of HLA single chain trimer design on peptide presentation and stability.", "doi": null, "pmid": null, "journal": "Front Immunol", "year": 2023, "authors": ["Finton, K.A.K.", "Rupert, P.B.", "Friend, D.J.", "Dinca, A.", "Lovelace, E.S.", "Buerger, M."]}, "related_emdb": []}, {"pdb_id": "7SR3", "title": "Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL", "keywords": "IMMUNE SYSTEM", "resolution": 2.49, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-11-07T00:00:00.000+00:00", "release_date": "2022-11-23T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera", "length": 427}], "ligands": [], "primary_citation": {"title": "Effects of HLA single chain trimer design on peptide presentation and stability.", "doi": null, "pmid": null, "journal": "Front Immunol", "year": 2023, "authors": ["Finton, K.A.K.", "Rupert, P.B.", "Friend, D.J.", "Dinca, A.", "Lovelace, E.S.", "Buerger, M."]}, "related_emdb": []}, {"pdb_id": "7SR4", "title": "Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDLYC", "keywords": "IMMUNE SYSTEM", "resolution": 2.59, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-11-07T00:00:00.000+00:00", "release_date": "2022-11-23T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera", "length": 429}], "ligands": [], "primary_citation": {"title": "Effects of HLA single chain trimer design on peptide presentation and stability.", "doi": null, "pmid": null, "journal": "Front Immunol", "year": 2023, "authors": ["Finton, K.A.K.", "Rupert, P.B.", "Friend, D.J.", "Dinca, A.", "Lovelace, E.S.", "Buerger, M."]}, "related_emdb": []}, {"pdb_id": "7SR5", "title": "Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL", "keywords": "IMMUNE SYSTEM", "resolution": 2.35, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-11-07T00:00:00.000+00:00", "release_date": "2022-11-23T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Wilms tumor protein peptide,Beta-2-microglobulin,MHC class I antigen chimera", "length": 424}], "ligands": [], "primary_citation": {"title": "Effects of HLA single chain trimer design on peptide presentation and stability.", "doi": null, "pmid": null, "journal": "Front Immunol", "year": 2023, "authors": ["Finton, K.A.K.", "Rupert, P.B.", "Friend, D.J.", "Dinca, A.", "Lovelace, E.S.", "Buerger, M."]}, "related_emdb": []}, {"pdb_id": "9NFB", "title": "Structure of the cross-HLA supertype antibody R302 bound to a class I MHC presenting a divarasib-modified KRAS-G12C peptide on HLA-A*02", "keywords": "PROTEIN BINDING", "resolution": 3.23, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-02-21T00:00:00.000+00:00", "release_date": "2025-10-08T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A"], "description": "MHC class I antigen", "length": 307}], "ligands": [{"comp_id": "1-{(3S)-4-[(7M)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-", "chem_id": "A1AWR"}], "primary_citation": {"title": "Engineered antibodies that stabilize drug-modified KRAS G12C neoantigens enable selective and potent cross-HLA immunotherapy.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2025, "authors": ["Maso, L.", "Mosure, S.A.", "Rodriguez-Aponte, S.A.", "Pizzo, A.", "Mensah, D.N.", "Southard, M."]}, "related_emdb": ["EMD-49361"]}]}, "alphafold": {"uniprot_id": "A0A6S7XV52", "model_count": 1, "models": [{"entryId": "AF-A0A6S7XV52-F1", "uniprotAccession": "A0A6S7XV52", "uniprotDescription": "MHC class I antigen", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 85.12, "modelCreatedDate": "2022-06-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A6S7XV52-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A6S7XV52-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0A6S7XV52-F1-predicted_aligned_error_v6.png"}]}, "emdb": {"uniprot_id": "A0A6S7XV52", "emdb_count": 1, "entries": [{"emdb_id": "EMD-49361", "title": null, "resolution_A": null, "deposit_date": "2025-02-21T00:00:00", "release_date": "2025-10-08T00:00:00", "method": "electron microscopy"}]}} | 2026-05-27T10:45:01.783962+00:00 |