target_layer1_structure: A0A9P1NJI6
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A9P1NJI6 | 6 | 6 | 0 | 0 | 0 | 1 | 0 | {"pdb": {"uniprot_id": "A0A9P1NJI6", "pdb_count_total": 6, "pdb_count_detailed": 6, "entries": [{"pdb_id": "8BJH", "title": "chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin", "keywords": "TOXIN", "resolution": 1.69, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-04T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Putative Adenylate cyclase,Profilin-1", "length": 591}], "ligands": [{"comp_id": "ADENOSINE-5'-DIPHOSPHATE", "chem_id": "ADP"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "LATRUNCULIN B", "chem_id": "LAB"}, {"comp_id": "2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "TRS"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "HYDROGEN PEROXIDE", "chem_id": "PEO"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "DI(HYDROXYETHYL)ETHER", "chem_id": "PEG"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}, {"pdb_id": "8BJI", "title": "chimera of ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo fused to a proline-Rich-Domain (PRD) and profilin, bound to ADP-Mg-actin and a sulfate ion", "keywords": "TOXIN", "resolution": 1.75, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-04T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Putative Adenylate cyclase,Profilin-1", "length": 591}], "ligands": [{"comp_id": "ADENOSINE-5'-DIPHOSPHATE", "chem_id": "ADP"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "TRS"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "DI(HYDROXYETHYL)ETHER", "chem_id": "PEG"}, {"comp_id": "HYDROGEN PEROXIDE", "chem_id": "PEO"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}, {"pdb_id": "8BJJ", "title": "ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion", "keywords": "TOXIN", "resolution": 1.699, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-04T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "3", "chains": ["B"], "description": "Putative Adenylate cyclase", "length": 413}], "ligands": [{"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "LATRUNCULIN B", "chem_id": "LAB"}, {"comp_id": "2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL", "chem_id": "TRS"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "HYDROGEN PEROXIDE", "chem_id": "PEO"}, {"comp_id": "TETRAETHYLENE GLYCOL", "chem_id": "PG4"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}, {"pdb_id": "8BO1", "title": "ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions", "keywords": "TOXIN", "resolution": 2.501, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-14T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B", "D"], "description": "Putative Adenylate cyclase", "length": 413}], "ligands": [{"comp_id": "LATRUNCULIN B", "chem_id": "LAB"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "3'-DEOXYADENOSINE-5'-TRIPHOSPHATE", "chem_id": "3AT"}, {"comp_id": "MANGANESE (II) ION", "chem_id": "MN"}, {"comp_id": "AZIDE ION", "chem_id": "AZI"}, {"comp_id": "CHLORIDE ION", "chem_id": "CL"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}, {"pdb_id": "8BR0", "title": "ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin", "keywords": "TOXIN", "resolution": 2.218, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-22T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B", "D"], "description": "Putative Adenylate cyclase,Profilin-1", "length": 591}], "ligands": [{"comp_id": "LATRUNCULIN B", "chem_id": "LAB"}, {"comp_id": "ADENOSINE-5'-DIPHOSPHATE", "chem_id": "ADP"}, {"comp_id": "MANGANESE (II) ION", "chem_id": "MN"}, {"comp_id": "3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE", "chem_id": "CH1"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}, {"pdb_id": "8BR1", "title": "ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions", "keywords": "TOXIN", "resolution": 2.044, "method": "X-RAY DIFFRACTION", "deposit_date": "2022-11-22T00:00:00.000+00:00", "release_date": "2023-09-20T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B", "D"], "description": "Putative Adenylate cyclase", "length": 413}], "ligands": [{"comp_id": "LATRUNCULIN B", "chem_id": "LAB"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "3'-DEOXYADENOSINE-5'-TRIPHOSPHATE", "chem_id": "3AT"}, {"comp_id": "SULFATE ION", "chem_id": "SO4"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "HYDROGEN PEROXIDE", "chem_id": "PEO"}], "primary_citation": {"title": "Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.", "doi": null, "pmid": null, "journal": "PLoS Pathog", "year": 2023, "authors": ["Teixeira-Nunes, M.", "Retailleau, P.", "Raoux-Barbot, D.", "Comisso, M.", "Missinou, A.A.", "Velours, C."]}, "related_emdb": []}]}, "alphafold": {"uniprot_id": "A0A9P1NJI6", "model_count": 0, "_note": "no AlphaFold prediction"}, "emdb": {"uniprot_id": "A0A9P1NJI6", "emdb_count": 0, "entries": []}} | 2026-05-27T10:45:02.454512+00:00 |