target_layer1_structure: A0AVT1
This data as json
| target_id | pdb_count_total | pdb_count_detailed | pdb_best_resolution_A | alphafold_mean_pLDDT | alphafold_model_count | emdb_count | has_cryoEM | has_xray | has_NMR | raw_json | recorded_utc |
|---|---|---|---|---|---|---|---|---|---|---|---|
| A0AVT1 | 14 | 14 | 91.44 | 4 | 14 | 1 | 1 | 0 | {"pdb": {"uniprot_id": "A0AVT1", "pdb_count_total": 14, "pdb_count_detailed": 14, "entries": [{"pdb_id": "7PVN", "title": "Crystal Structure of Human UBA6 in Complex with ATP", "keywords": "HYDROLASE", "resolution": 2.71, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-10-05T00:00:00.000+00:00", "release_date": "2022-08-31T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1052}], "ligands": [{"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}, {"comp_id": "GLYCEROL", "chem_id": "GOL"}, {"comp_id": "MAGNESIUM ION", "chem_id": "MG"}, {"comp_id": "CALCIUM ION", "chem_id": "CA"}, {"comp_id": "CHLORIDE ION", "chem_id": "CL"}], "primary_citation": {"title": "Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Truongvan, N.", "Li, S.", "Misra, M.", "Kuhn, M.", "Schindelin, H."]}, "related_emdb": []}, {"pdb_id": "7PYV", "title": "Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10", "keywords": "HYDROLASE", "resolution": 3.27, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-10-11T00:00:00.000+00:00", "release_date": "2022-08-24T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "B"], "description": "Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-like modifier-activating enzyme 1,Ubiquitin-like modifier-activating enzyme 6", "length": 1045}], "ligands": [], "primary_citation": {"title": "Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Truongvan, N.", "Li, S.", "Misra, M.", "Kuhn, M.", "Schindelin, H."]}, "related_emdb": []}, {"pdb_id": "7SOL", "title": "Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6", "keywords": "SIGNALING PROTEIN/Ligase", "resolution": 2.25000635563, "method": "X-RAY DIFFRACTION", "deposit_date": "2021-10-31T00:00:00.000+00:00", "release_date": "2022-11-02T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["A", "C"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1020}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE MONOPHOSPHATE", "chem_id": "AMP"}], "primary_citation": {"title": "Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.", "doi": null, "pmid": null, "journal": "Nat Commun", "year": 2022, "authors": ["Yuan, L.", "Gao, F.", "Lv, Z.", "Nayak, D.", "Nayak, A.", "Santos Bury, P.D."]}, "related_emdb": []}, {"pdb_id": "9QGW", "title": "Consensus structure of UBA6-UbDha-BIRC6 trapped ternary complex (singly loaded)", "keywords": "LIGASE", "resolution": 3.62, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-14T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QH5", "title": "Consensus structure of UBA6-UbDha-BIRC6 trapped ternary complex (doubly loaded)", "keywords": "LIGASE", "resolution": 3.09, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-14T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE MONOPHOSPHATE", "chem_id": "AMP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QHI", "title": "Structure of UBA6-UbDha-BIRC6 trapped ternary complex (cluster 0)", "keywords": "LIGASE", "resolution": 4.27, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-15T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE MONOPHOSPHATE", "chem_id": "AMP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIA", "title": "Structure of UBA6-UbDha-BIRC6 trapped ternary complex (cluster 2)", "keywords": "LIGASE", "resolution": 4.38, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-18T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE MONOPHOSPHATE", "chem_id": "AMP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195", "EMD-53183"]}, {"pdb_id": "9QIC", "title": "Consensus structure of UBA6", "keywords": "LIGASE", "resolution": 3.29, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIG", "title": "Structure of UBA6 (cluster 2)", "keywords": "LIGASE", "resolution": 3.94, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QII", "title": "Structure of UBA6 (cluster 3)", "keywords": "LIGASE", "resolution": 3.99, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "1", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIM", "title": "Consensus structure of UBA6-BIRC6", "keywords": "LIGASE", "resolution": 3.57, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIO", "title": "Structure of UBA6-BIRC6 (cluster 0)", "keywords": "LIGASE", "resolution": 4.22, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIP", "title": "Structure of UBA6-BIRC6 (cluster 4)", "keywords": "LIGASE", "resolution": 4.15, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}, {"pdb_id": "9QIV", "title": "Consensus structure of UBA6-BIRC6 (alternative conformation)", "keywords": "LIGASE", "resolution": 3.44, "method": "ELECTRON MICROSCOPY", "deposit_date": "2025-03-17T00:00:00.000+00:00", "release_date": "2025-10-29T00:00:00.000+00:00", "my_uniprot_chains": [{"entity_id": "2", "chains": ["B"], "description": "Ubiquitin-like modifier-activating enzyme 6", "length": 1054}], "ligands": [{"comp_id": "INOSITOL HEXAKISPHOSPHATE", "chem_id": "IHP"}, {"comp_id": "ADENOSINE-5'-TRIPHOSPHATE", "chem_id": "ATP"}], "primary_citation": {"title": "UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6.", "doi": null, "pmid": null, "journal": "Nat Struct Mol Biol", "year": 2026, "authors": ["Riechmann, C.", "Ellison, C.J.", "Anderson, J.W.", "Hofmann, K.", "Sarkies, P.", "Elliott, P.R."]}, "related_emdb": ["EMD-53130", "EMD-53131", "EMD-53147", "EMD-53149", "EMD-53155", "EMD-53170", "EMD-53183", "EMD-53184", "EMD-53187", "EMD-53188", "EMD-53190", "EMD-53192", "EMD-53193", "EMD-53195"]}]}, "alphafold": {"uniprot_id": "A0AVT1", "model_count": 4, "models": [{"entryId": "AF-A0AVT1-F1", "uniprotAccession": "A0AVT1", "uniprotDescription": "Ubiquitin-like modifier-activating enzyme 6", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 91.44, "modelCreatedDate": "2025-08-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-F1-predicted_aligned_error_v6.png"}, {"entryId": "AF-A0AVT1-4-F1", "uniprotAccession": "A0AVT1-4", "uniprotDescription": "Ubiquitin-like modifier-activating enzyme 6", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 85.94, "modelCreatedDate": "2025-08-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-4-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-4-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-4-F1-predicted_aligned_error_v6.png"}, {"entryId": "AF-A0AVT1-3-F1", "uniprotAccession": "A0AVT1-3", "uniprotDescription": "Ubiquitin-like modifier-activating enzyme 6", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 86.5, "modelCreatedDate": "2025-08-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-3-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-3-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-3-F1-predicted_aligned_error_v6.png"}, {"entryId": "AF-A0AVT1-2-F1", "uniprotAccession": "A0AVT1-2", "uniprotDescription": "Ubiquitin-like modifier-activating enzyme 6", "organismScientificName": "Homo sapiens", "sequenceLength": null, "globalMetricValue": 92.81, "modelCreatedDate": "2025-08-01T00:00:00Z", "latestVersion": 6, "cifUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-2-F1-model_v6.cif", "pdbUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-2-F1-model_v6.pdb", "paeImageUrl": "https://alphafold.ebi.ac.uk/files/AF-A0AVT1-2-F1-predicted_aligned_error_v6.png"}]}, "emdb": {"uniprot_id": "A0AVT1", "emdb_count": 14, "entries": [{"emdb_id": "EMD-53130", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53131", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53147", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53149", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53155", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53170", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53183", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53184", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53187", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53188", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53190", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53192", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53193", "_error": "'list' object has no attribute 'get'"}, {"emdb_id": "EMD-53195", "_error": "'list' object has no attribute 'get'"}]}} | 2026-05-27T10:45:01.558156+00:00 |