EV-Map conserved proteome (Rai & Greening 2025)

The complete EV-Map conserved molecular signature (Rai & Greening 2025, Nat Cell Biol 10.1038/s41556-025-01795-7): 182 conserved EV-hallmark proteins + 42 non-EV (lipoprotein-network) proteins. in_apt_scout = 1 if the protein is an apt-scout target (104 of the 182 EV-hallmark + 25 of the 42 non-EV are; the rest are reference-only, outside apt-scout's target universe). Source: paper Supplementary Table 7.

Data license: CC BY 4.0 · Data source: apt-scout automated curation pipeline (E. Dohi, NCNP) — values harvested from public databases; raw source stored per target

gene_name
Gene symbol.
feature
EV-hallmark (conserved EV) or non-EV (lipoprotein-network).
category
EV-Map conservation category (1/2/3/Rest).
in_apt_scout
1 if this protein is an apt-scout target.
apt_scout_uniprot
apt-scout target UniProt (if in_apt_scout=1).

17 rows where feature = "non-EV" and in_apt_scout = 0

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category 4

in_apt_scout 1

feature 1

  • non-EV · 17 ✖
Link rowid ▼ gene_name feature category misev_marker entrezgene_id pevs_median in_apt_scout apt_scout_uniprot
30 30 SERPING1 non-EV Category 1   710 25.77602287 0  
31 31 SERPINF2 non-EV Category 1   5345 24.95654127 0  
62 62 PON1 non-EV Category 1   5444 25.26189032 0  
75 75 ORM1 non-EV Category 1   5004 25.26127749 0  
94 94 ITIH3 non-EV Category 3   3699 21.59465937 0  
95 95 ITIH2 non-EV Category 1   3698 27.50080873 0  
130 130 IGHG4 non-EV Category 1     28.24915617 0  
136 136 HPX non-EV Category 1   3263 27.09408196 0  
158 158 FBLN1 non-EV Rest   2192 21.85894765 0  
160 160 F2 non-EV Category 1   2147 25.48847607 0  
161 161 F13B non-EV Rest   2165 22.01963417 0  
176 176 CFI non-EV Category 1   3426 23.0706348 0  
208 208 APOB non-EV Category 1   338 27.32785537 0  
209 209 APOA4 non-EV Category 1   337 25.8536907 0  
215 215 AMBP non-EV Category 1   259 26.03843225 0  
217 217 AHSG non-EV Category 1   197 25.54351737 0  
224 224 A1BG non-EV Category 2   1 25.43002533 0  

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CREATE TABLE ev_map_conserved (gene_name TEXT, feature TEXT, category TEXT,
             misev_marker TEXT, entrezgene_id TEXT, pevs_median TEXT,
             in_apt_scout INTEGER, apt_scout_uniprot TEXT);